Re-introduction of azathioprine in previously intolerant patients

European Journal of Gastroenterology and Hepatology

Volumn 18, Issue 1, 2006, Pages 17-19

  Green, Caroline J ^a   Mee, Anthony S ^a  

^a ROYAL BERKSHIRE HOSPITAL   (United Kingdom)

Author keywords

Adverse effects; Azathioprine; Inflammatory bowel disease

Indexed keywords

AZATHIOPRINE; MERCAPTOPURINE; METHOTREXATE; PREDNISOLONE;

ADULT; AGED; ARTHRALGIA; ARTICLE; BACKACHE; CLINICAL ARTICLE; DESENSITIZATION; DIARRHEA; DOSE RESPONSE; DRUG TOLERABILITY; DYSPEPSIA; ENTERITIS; FEMALE; FEVER; FLU LIKE SYNDROME; GASTROENTEROLOGY; HEADACHE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LEUKOPENIA; MALE; MYALGIA; NAUSEA; PRIORITY JOURNAL; RASH; URTICARIA; VOMITING;

ADULT; AGED; AZATHIOPRINE; COLITIS, ULCERATIVE; CROHN DISEASE; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATORY BOWEL DISEASES; MALE; MIDDLE AGED; RECURRENCE; TREATMENT OUTCOME;

EID: 29344468038     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200601000-00004     Document Type: Article

References (8)

1. McGovern DPM, Travis SPL. Thiopurine therapy: when to start and when to stop. Eur J Gastroenterol Hepatol 2003; 15:219-223.
2. Louis E. Optimizing treatment with thioguanine derivatives in inflammatory bowel disease. Best Prac Res Curr Gastroenterol 2003; 17:37-46.
3. Sandborn WJ. Azathioprine: state of the art in inflammatory bowel disease. Scand J Gastroenterol 1998; 33 (suppl 225):92-99.
4. Taffet SL, Das KM. Sulfasalazine. Adverse effects and desensitization. Dig Dis Sci 1983; 28:833-841.
5. Connell WR, Kamm MA, Ritchie JK, Lennard-Jones JE. Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years experience. Gut 1993; 34:1081-1085.
6. Dubinsky MC, Feldman EJ, Abreu MM, Targan SR, Vasiliauskas EA. Thioguanine: a potential alternative thiopurine for inflammatory bowel disease patients allergic to 6-mercaptopurine or azathioprine. Am J Gastroenterol 2003; 98:1058-1063.
7. Baker BE. Pharmacogenomics of azathioprine and 6-mercaptopurine in gastroenterologic therapy. Rev Gastroenterol Dis 2003; 3:150-157.
8. Alstead EM, Ritchie JK, Lennard-Jones JE, Farthing MJ, Clark ML. Safety of azathioprine in pregnancy in inflammatory bowel disease. Gastroenterology 1990; 99:443-446.