Reactivity of various recombinant human cytochrome P450 isoforms for hydroxylation of triazolam in vitro

Japanese Journal of Forensic Toxicology

Volumn 23, Issue 3, 2005, Pages 205-208

  Shinozuka, Tatsuo ^a,b   Kurihara, Katsuyoshi ^b   Yamamoto, Ken ^c   Tanaka, Einosuke ^d   Terada, Masaru ^e  

^a KEIO UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KANTO CHEMICAL CO INC   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

^e TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Hydroxylation; 4 Hydroxylation; Baculovirus infected insect cells; CYP; Cytochrome P450 isoforms; Recombinat CYPs; Triazolam

Indexed keywords

4 HYDROXYTRIAZOLAM; ALPHA HYDROXYTRIAZOLAM; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DRUG METABOLITE; ISOPROTEIN; RECOMBINANT PROTEIN; TRIAZOLAM; UNCLASSIFIED DRUG;

ARTICLE; BACULOVIRUS; CONCENTRATION (PARAMETERS); DRUG DETERMINATION; DRUG HYDROXYLATION; IN VITRO STUDY; INSECT CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; VIRUS INFECTION;

INSECTA;

EID: 29344455878     PISSN: 09159606     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

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