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Volumn 29, Issue 6, 2005, Pages 421-428

Brain specific proteins in cerebrospinal fluid (CSF): Factors influencing their concentration in CSF and clinical relevance;ZNS-proteine im liquor: Einflussfaktoren auf ihre konzentration im liquor und klinische relevanz

Author keywords

Blood brain barrier; Blood CSF barrier; Brain specific proteins; Cerebrospinal fluid

Indexed keywords

BRAIN PROTEIN; TAU PROTEIN;

EID: 29344452502     PISSN: 03423026     EISSN: 14390477     Source Type: Journal    
DOI: 10.1515/JLM.2005.057     Document Type: Review
Times cited : (5)

References (45)
  • 1
    • 84942960794 scopus 로고
    • Neuronal acetylcholinesterase levels in cerebrospinal fluid and serum determined by a specific and sensitive immunoassay
    • Mäder M, Soerensen K, Wiedmann T, Dickmann U, Felgenhauer K. Neuronal acetylcholinesterase levels in cerebrospinal fluid and serum determined by a specific and sensitive immunoassay. Eur J Clin Chem Clin Biochem 1991;29:51-5.
    • (1991) Eur J Clin Chem Clin Biochem , vol.29 , pp. 51-55
    • Mäder, M.1    Soerensen, K.2    Wiedmann, T.3    Dickmann, U.4    Felgenhauer, K.5
  • 2
    • 0025655717 scopus 로고
    • Cerebrospinal fluid markers in neurological disorders
    • Massaro AR, Scivoletto G, Tonali P. Cerebrospinal fluid markers in neurological disorders. Ital J Neurol Sci 1990;11:537-47.
    • (1990) Ital J Neurol Sci , vol.11 , pp. 537-547
    • Massaro, A.R.1    Scivoletto, G.2    Tonali, P.3
  • 3
    • 0025062357 scopus 로고
    • Detection of neuron specific enolase concentrations in cerebrospinal fluid from patients with neurological disorders by means of a sensitive enzyme immunoassay
    • Vermuyten K, Lowenthal A, Karcher D. Detection of neuron specific enolase concentrations in cerebrospinal fluid from patients with neurological disorders by means of a sensitive enzyme immunoassay. Clin Chim Acta 1990;187:69-78.
    • (1990) Clin Chim Acta , vol.187 , pp. 69-78
    • Vermuyten, K.1    Lowenthal, A.2    Karcher, D.3
  • 5
    • 0022775491 scopus 로고
    • The blood-brain barrier
    • Goldstein GW, Betz AL. The blood-brain barrier. Sci Am 1986;255:74-83.
    • (1986) Sci Am , vol.255 , pp. 74-83
    • Goldstein, G.W.1    Betz, A.L.2
  • 6
    • 0017736628 scopus 로고
    • The blood-brain barrier to horseradish peroxidase under normal and experimental conditions
    • Westergaard E. The blood-brain barrier to horseradish peroxidase under normal and experimental conditions. Acta Neuropathol Berl 1977;39:181-7.
    • (1977) Acta Neuropathol Berl , vol.39 , pp. 181-187
    • Westergaard, E.1
  • 8
    • 0017193105 scopus 로고
    • Evaluation of the blood-CSF barrier by protein gradients and the humoral immune response within the central nervous system
    • Felgenhauer K, Schliep G, Rapic N. Evaluation of the blood-CSF barrier by protein gradients and the humoral immune response within the central nervous system. J Neurol Sci 1976;30:113-28.
    • (1976) J Neurol Sci , vol.30 , pp. 113-128
    • Felgenhauer, K.1    Schliep, G.2    Rapic, N.3
  • 9
    • 0023112582 scopus 로고
    • Protein transfer at the blood cerebrospinal fluid barrier and the quantitation of the humoral immune response within the central nervous system
    • Reiber H, Felgenhauer K. Protein transfer at the blood cerebrospinal fluid barrier and the quantitation of the humoral immune response within the central nervous system. Clin Chim Acta 1987;163:319-28.
    • (1987) Clin Chim Acta , vol.163 , pp. 319-328
    • Reiber, H.1    Felgenhauer, K.2
  • 10
    • 0022870607 scopus 로고
    • The clinical relevance of locally produced carcinoembryonic antigen in cerebrospinal fluid
    • Jacobi C, Reiber H, Felgenhauer K. The clinical relevance of locally produced carcinoembryonic antigen in cerebrospinal fluid. J Neurol 1986;233:358-61.
    • (1986) J Neurol , vol.233 , pp. 358-361
    • Jacobi, C.1    Reiber, H.2    Felgenhauer, K.3
  • 11
    • 0000806552 scopus 로고
    • Proteins in cerebrospinal fluid not found in serum
    • Clausen J. Proteins in cerebrospinal fluid not found in serum. Proc Soc Exp Biol Med 1961;107:170-2.
    • (1961) Proc Soc Exp Biol Med , vol.107 , pp. 170-172
    • Clausen, J.1
  • 12
    • 0023255796 scopus 로고
    • Beta trace-protein as marker for cerebrospinal fluid fistula
    • Felgenhauer K, Schadlich HJ, Nekic M. Beta trace-protein as marker for cerebrospinal fluid fistula. Klin Wochenschr 1987;65:764-8.
    • (1987) Klin Wochenschr , vol.65 , pp. 764-768
    • Felgenhauer, K.1    Schadlich, H.J.2    Nekic, M.3
  • 13
    • 0345493900 scopus 로고    scopus 로고
    • Expression of the beta-trace protein in human pachymeninx as revealed by in situ hybridization and immunocytochemistry
    • Blödorn B, Brück W, Tumani H, Michel U, Rieckmann P, Althans N, et al. Expression of the beta-trace protein in human pachymeninx as revealed by in situ hybridization and immunocytochemistry. J Neurosci Res 1999;57:730-4.
    • (1999) J Neurosci Res , vol.57 , pp. 730-734
    • Blödorn, B.1    Brück, W.2    Tumani, H.3    Michel, U.4    Rieckmann, P.5    Althans, N.6
  • 14
    • 0031768283 scopus 로고    scopus 로고
    • Beta-trace protein in cerebrospinal fluid: A blood-CSF barrier-related evaluation in neurological diseases
    • Tumani H, Nau R, Felgenhauer K. Beta-trace protein in cerebrospinal fluid: a blood-CSF barrier-related evaluation in neurological diseases. Ann Neurol 1998;44:882-9.
    • (1998) Ann Neurol , vol.44 , pp. 882-889
    • Tumani, H.1    Nau, R.2    Felgenhauer, K.3
  • 15
    • 0025182959 scopus 로고
    • Adhesion receptors of the immune system
    • Springer TA. Adhesion receptors of the immune system. Nature 1990;346:425-34.
    • (1990) Nature , vol.346 , pp. 425-434
    • Springer, T.A.1
  • 16
    • 0032127023 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1 in cerebrospinal fluid - The evaluation of blood-derived and brain-derived fractions in neurological diseases
    • Lewczuk P, Reiber H, Tumani H. Intercellular adhesion molecule-1 in cerebrospinal fluid - the evaluation of blood-derived and brain-derived fractions in neurological diseases. J Neuroimmunol 1998;87:156-61.
    • (1998) J Neuroimmunol , vol.87 , pp. 156-161
    • Lewczuk, P.1    Reiber, H.2    Tumani, H.3
  • 17
    • 0017579832 scopus 로고
    • Glutamine synthetase: Glial localization in brain
    • Martinez HA, Bell KP, Norenberg MD. Glutamine synthetase: glial localization in brain. Science 1977;195:1356-8.
    • (1977) Science , vol.195 , pp. 1356-1358
    • Martinez, H.A.1    Bell, K.P.2    Norenberg, M.D.3
  • 18
    • 0032983595 scopus 로고    scopus 로고
    • Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type
    • Donato R. Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type. Biochim Biophys Acta 1999;1450:191-231.
    • (1999) Biochim Biophys Acta , vol.1450 , pp. 191-231
    • Donato, R.1
  • 20
    • 0022365608 scopus 로고
    • The distribution of tau in the mammalian central nervous system
    • Binder LI, Frankfurter A, Rebhun LI. The distribution of tau in the mammalian central nervous system. J Cell Biol 1985;101:1371-8.
    • (1985) J Cell Biol , vol.101 , pp. 1371-1378
    • Binder, L.I.1    Frankfurter, A.2    Rebhun, L.I.3
  • 21
    • 0027374233 scopus 로고
    • Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay
    • Vandermeeren M, Mercken M, Vanmechelen E, Six J, van de Voorde A, Martin JJ, et al. Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay. J Neurochem 1993;61:1828-34.
    • (1993) J Neurochem , vol.61 , pp. 1828-1834
    • Vandermeeren, M.1    Mercken, M.2    Vanmechelen, E.3    Six, J.4    Van De Voorde, A.5    Martin, J.J.6
  • 22
    • 0027976814 scopus 로고
    • Neuron-specific enolase concentrations in blood as a prognostic parameter in cerebrovascular diseases
    • Schaarschmidt H, Prange HW, Reiber H. Neuron-specific enolase concentrations in blood as a prognostic parameter in cerebrovascular diseases. Stroke 1994;25:558-65.
    • (1994) Stroke , vol.25 , pp. 558-565
    • Schaarschmidt, H.1    Prange, H.W.2    Reiber, H.3
  • 24
    • 0028850301 scopus 로고
    • Relevance of cerebrospinal fluid variables for early diagnosis of neuroborreliosis
    • Tumani H, Nolker G, Reiber H. Relevance of cerebrospinal fluid variables for early diagnosis of neuroborreliosis. Neurology 1995;45:1663-70.
    • (1995) Neurology , vol.45 , pp. 1663-1670
    • Tumani, H.1    Nolker, G.2    Reiber, H.3
  • 25
    • 25144468377 scopus 로고    scopus 로고
    • Isolated blood-cerebrospinal fluid barrier dysfunction: Prevalence and associated diseases
    • Epub April 1
    • Brettschneider J, Claus A, Kassubek J, Tumani H. Isolated blood-cerebrospinal fluid barrier dysfunction: prevalence and associated diseases. J Neurol 2005; Epub April 1.
    • (2005) J Neurol
    • Brettschneider, J.1    Claus, A.2    Kassubek, J.3    Tumani, H.4
  • 26
    • 0028269876 scopus 로고
    • Flow rate of cerebrospinal fluid (CSF) - A concept common to normal blood-CSF barrier function and to dysfunction in neurological diseases
    • Reiber H. Flow rate of cerebrospinal fluid (CSF) - a concept common to normal blood-CSF barrier function and to dysfunction in neurological diseases. J Neurol Sci 1994; 122:189-203.
    • (1994) J Neurol Sci , vol.122 , pp. 189-203
    • Reiber, H.1
  • 27
    • 0031056637 scopus 로고    scopus 로고
    • Soluble adhesion molecules (sVCAM-1 and sICAM-1) in cerebrospinal fluid and serum correlate with MRI activity in multiple sclerosis
    • Rieckmann P, Altenhofen B, Riegel A, Baudewig J, Felgenhauer K. Soluble adhesion molecules (sVCAM-1 and sICAM-1) in cerebrospinal fluid and serum correlate with MRI activity in multiple sclerosis. Ann Neurol 1997;41:326-33.
    • (1997) Ann Neurol , vol.41 , pp. 326-333
    • Rieckmann, P.1    Altenhofen, B.2    Riegel, A.3    Baudewig, J.4    Felgenhauer, K.5
  • 28
    • 9844234269 scopus 로고    scopus 로고
    • S-100 protein concentration in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
    • Otto M, Stein H, Szudra A, Zerr I, Bodemer M, Gefeller O, et al. S-100 protein concentration in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. J Neurol 1997;244:566-70.
    • (1997) J Neurol , vol.244 , pp. 566-570
    • Otto, M.1    Stein, H.2    Szudra, A.3    Zerr, I.4    Bodemer, M.5    Gefeller, O.6
  • 30
    • 0030934518 scopus 로고    scopus 로고
    • Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
    • Otto M, Wiltfang J, Tumani H, Zerr I, Lantsch M, Kornhuber J, et al. Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Neurosci Lett 1997;225:210-2.
    • (1997) Neurosci Lett , vol.225 , pp. 210-212
    • Otto, M.1    Wiltfang, J.2    Tumani, H.3    Zerr, I.4    Lantsch, M.5    Kornhuber, J.6
  • 31
    • 0032775645 scopus 로고    scopus 로고
    • Cisternal S100 protein and neuron-specific enolase are elevated and site-specific markers in intractable temporal lobe epilepsy
    • Steinhoff BJ, Tumani H, Otto M, Mursch K, Wiltfang J, Herrendorf G, et al. Cisternal S100 protein and neuron-specific enolase are elevated and site-specific markers in intractable temporal lobe epilepsy. Epilepsy Res 1999;36:75-82.
    • (1999) Epilepsy Res , vol.36 , pp. 75-82
    • Steinhoff, B.J.1    Tumani, H.2    Otto, M.3    Mursch, K.4    Wiltfang, J.5    Herrendorf, G.6
  • 33
    • 0035691112 scopus 로고    scopus 로고
    • CSF total tau, Aβ42 and phosphorylated tau as biomarkers for Alzheimer's disease
    • Blennow K, Vanmechelen E, Hampel H. CSF total tau, Aβ42 and phosphorylated tau as biomarkers for Alzheimer's disease. Mol Neurobiol 2001;24:87-97.
    • (2001) Mol Neurobiol , vol.24 , pp. 87-97
    • Blennow, K.1    Vanmechelen, E.2    Hampel, H.3
  • 34
    • 20944439059 scopus 로고    scopus 로고
    • Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease
    • Grossman M, Farmer J, Leight S, Work M, Moore P, Van Deerlin V, et al. Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease. Ann Neurol 2005;57:721-9.
    • (2005) Ann Neurol , vol.57 , pp. 721-729
    • Grossman, M.1    Farmer, J.2    Leight, S.3    Work, M.4    Moore, P.5    Van Deerlin, V.6
  • 35
    • 17544398505 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: Disease stage related changes of tau protein and S100 beta in cerebrospinal fluid and creatine kinase in serum
    • Sussmuth SD, Tumani H, Ecker D, Ludolph AC. Amyotrophic lateral sclerosis: disease stage related changes of tau protein and S100 beta in cerebrospinal fluid and creatine kinase in serum. Neurosci Lett 2003;353:57-60.
    • (2003) Neurosci Lett , vol.353 , pp. 57-60
    • Sussmuth, S.D.1    Tumani, H.2    Ecker, D.3    Ludolph, A.C.4
  • 36
    • 20144377153 scopus 로고    scopus 로고
    • Tau protein level in cerebrospinal fluid is increased in patients with early multiple sclerosis
    • Brettschneider J, Maier M, Arda S, Claus A, Sussmuth SD, Kassubek J, et al. Tau protein level in cerebrospinal fluid is increased in patients with early multiple sclerosis. Mult Scler 2005;11:261-5.
    • (2005) Mult Scler , vol.11 , pp. 261-265
    • Brettschneider, J.1    Maier, M.2    Arda, S.3    Claus, A.4    Sussmuth, S.D.5    Kassubek, J.6
  • 37
    • 4544266973 scopus 로고    scopus 로고
    • CSF biomarkers for mild cognitive impairment
    • Blennow K. CSF biomarkers for mild cognitive impairment. J Int Medicine 2004;256:224-34.
    • (2004) J Int Medicine , vol.256 , pp. 224-234
    • Blennow, K.1
  • 38
    • 0029871359 scopus 로고    scopus 로고
    • Microglial response to N-methyl-D-aspartate-mediated excitotoxicity in the immature rat brain
    • Acarin L, Gonzalez B, Castellano B, Castro AJ. Microglial response to N-methyl-D-aspartate-mediated excitotoxicity in the immature rat brain. J Comp Neurol 1996;367:361-74.
    • (1996) J Comp Neurol , vol.367 , pp. 361-374
    • Acarin, L.1    Gonzalez, B.2    Castellano, B.3    Castro, A.J.4
  • 39
    • 0032498826 scopus 로고    scopus 로고
    • Axotomy-induced neuronal death and reactive astrogliosis in the lateral geniculate nucleus following a lesion of the visual cortex in the rat
    • Agarwala S, Kalil RE. Axotomy-induced neuronal death and reactive astrogliosis in the lateral geniculate nucleus following a lesion of the visual cortex in the rat. J Comp Neurol 1998;392:252-63.
    • (1998) J Comp Neurol , vol.392 , pp. 252-263
    • Agarwala, S.1    Kalil, R.E.2
  • 40
    • 29344433975 scopus 로고    scopus 로고
    • Klinische Relevanz hirnspezifischer Proteine im Liquor und im Serum
    • Abstract
    • Tumani H, Reiber H, Steinhoff BJ, Felgenhauer K. Klinische Relevanz hirnspezifischer Proteine im Liquor und im Serum. Akt Neurologie 1999;26:S1(Abstract).
    • (1999) Akt Neurologie , vol.26
    • Tumani, H.1    Reiber, H.2    Steinhoff, B.J.3    Felgenhauer, K.4
  • 41
    • 0034023717 scopus 로고    scopus 로고
    • Inhibition of glutamine synthetase in rabbit pneumococcal meningitis is associated with neuronal apoptosis in the dentate gyrus
    • Tumani H, Smirnov A, Barchfeld S, Olgemöller U, Maier K, Lange P, et al. Inhibition of glutamine synthetase in rabbit pneumococcal meningitis is associated with neuronal apoptosis in the dentate gyrus. Glia 2000;30:11-8.
    • (2000) Glia , vol.30 , pp. 11-18
    • Tumani, H.1    Smirnov, A.2    Barchfeld, S.3    Olgemöller, U.4    Maier, K.5    Lange, P.6
  • 42
    • 0028327286 scopus 로고
    • Astrocyte responses to CNS injury
    • Norenberg MD. Astrocyte responses to CNS injury. J Neuropathol Exp Neurol 1994;53:213-20.
    • (1994) J Neuropathol Exp Neurol , vol.53 , pp. 213-220
    • Norenberg, M.D.1
  • 43
    • 0032873640 scopus 로고    scopus 로고
    • Glutamine synthetase in cerebrospinal fluid, serum, and brain: A diagnostic marker for Alzheimer disease?
    • Tumani H, Shen G, Peter JB, Brück W. Glutamine synthetase in cerebrospinal fluid, serum, and brain: a diagnostic marker for Alzheimer disease? Arch Neurol 1999;56:1241-6.
    • (1999) Arch Neurol , vol.56 , pp. 1241-1246
    • Tumani, H.1    Shen, G.2    Peter, J.B.3    Brück, W.4
  • 44
    • 0031596271 scopus 로고    scopus 로고
    • Combination of the different biological markers for increasing specificity of in vivo Alzheimer's testing
    • Blennow K, Vanmechelen E. Combination of the different biological markers for increasing specificity of in vivo Alzheimer's testing. J Neural Transm Suppl 1998;53:223-35.
    • (1998) J Neural Transm Suppl , vol.53 , pp. 223-235
    • Blennow, K.1    Vanmechelen, E.2
  • 45
    • 0002348524 scopus 로고    scopus 로고
    • Acute optic neuritis: Combined immunological markers and magnetic resonance imaging predict subsequent development of multiple sclerosis
    • Tumani H, Tourtellotte WW, Peter JB, Felgenhauer K. Acute optic neuritis: combined immunological markers and magnetic resonance imaging predict subsequent development of multiple sclerosis. J Neurol Sci 1998;155:44-9.
    • (1998) J Neurol Sci , vol.155 , pp. 44-49
    • Tumani, H.1    Tourtellotte, W.W.2    Peter, J.B.3    Felgenhauer, K.4


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