Elevated plasma concentrations of haptoglobin in European brown bears during hibernation

Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology

Volumn 142, Issue 4, 2005, Pages 472-477

  Mominoki, Katsumi ^a,c   Morimatsu, Masami ^a,d   Karjalainen, Minna ^b   Hohtola, Esa ^b   Hissa, Raimo ^b   Saito, Masayuki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b UNIVERSITY OF OULU   (Finland)

^c EHIME UNIVERSITY   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Acute phase protein; C reactive protein; Fat metabolism; Haptoglobin; Hibernation; Ursus arctos; 1 antitrypsin; 2 macroglobulin

Indexed keywords

ACUTE PHASE PROTEIN; ALPHA 1 ANTITRYPSIN; ALPHA 2 MACROGLOBULIN; C REACTIVE PROTEIN; HAPTOGLOBIN;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ARTICLE; BEAR; BLOOD SAMPLING; FEMALE; HIBERNATION; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; SEASONAL VARIATION;

ANIMALIA; MAMMALIA; URSUS ARCTOS;

EID: 29244489277     PISSN: 10956433     EISSN: 15314332     Source Type: Journal    
DOI: 10.1016/j.cbpa.2005.09.017     Document Type: Article

References (30)

1. B.H. Bowman, and A. Kurosky Haptoglobin: the evolutionary product of duplication, unequal crossing over, and point mutation Adv. Hum. Genet. 12 1992 189 261
2. C. Chiellini, A. Bertacca, S.E. Novelli, C.Z. Gorgun, A. Ciccarone, A. Giordano, H. Xu, A. Soukas, M. Costa, D. Gandini, R. Dimitri, P. Bottone, P. Cecchetti, E. Pardini, L. Perego, R. Navalesi, F. Folli, L. Benzi, S. Cinti, J.M. Friedman, G.S. Hotamisligil, and M. Maffei Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFα J. Cell Physiol. 190 2002 251 258
3. C. Chiellini, F. Santini, A. Marsili, P. Berti, A. Bertacca, C. Pelosini, G. Scartabelli, E. Pardini, J. Lopez-Soriano, R. Centoni, A.M. Ciccarone, L. Benzi, P. Vitti, S. Del Prato, A. Pinchera, and M. Maffei Serum haptoglobin: a novel marker of adiposity in humans J. Clin. Endocrinol. Metab. 89 2005 2678 2683
4. J.G. Conner, P.D. Eckersall, J. Ferguson, and T.A. Douglas Acute phase response in the dog following surgical trauma Res. Vet. Sci. 45 1988 107 110
5. L.K. Duffy, R.T. Bowyer, J.W. Testa, and J.B. Faro Acute phase proteins and cytokines in Alaskan mammals as markers of chronic exposure to environmental pollutants Am. Fish. Soc. Symp. 18 1996 809 813
6. J.W. Eaton, P. Brandt, J.R. Mahoney, and J.T. Lee Jr. Haptoglobin: a natural bacteriostat Science 215 1982 691 693
7. P.D. Eckersall, and J.G. Conner Bovine and canine acute phase protein Vet. Res. Commun. 12 1988 169 178
8. J.N. Fain, S.W. Bahouth, and A.K. Madan Haptoglobin release by human adipose tissue in primary culture J. Lipid Res. 45 2004 536 542
9. W.E. Friedrichs, A.L. Navarijo-Ashbaugh, B.H. Bowman, and F. Yang Expression and inflammatory regulation of haptoglobin gene in adipocytes Biochem. Biophys. Res. Commun. 209 1995 250 256
10. M. Guppy The hibernating bear: why is it so hot, and why does it cycle urea through the gut? Trends Biochem. Sci. 11 1986 274 276
11. H.J. Harlow, T.D.I. Beck, L.M. Waltes, and S.S. Greenhouse Seasonal serum glucose, progesterone and cortisol levels of black bears (Ursus americanus) Can. J. Zool. 68 1990 183 187
12. R. Hissa, J. Siekkinen, E. Hohtola, S. Saarela, A. Hakala, and J. Pudas Seasonal patterns in the physiology of the European brown bear (Ursus arctos arctos) in Finland Comp. Biochem. Physiol., A 109 1994 781 791
13. H. Kitamura, A. Konno, M. Morimatsu, B.D. Jung, K. Kimura, and M. Saito Immobilization stress increases hepatic IL-6 expression in mice Biochem. Biophys. Res. Commun. 238 1997 707 711
14. N. Kondo, and J. Kondo Identification of novel blood proteins specific for mammalian hibernation J. Biol. Chem. 267 1992 473 478
15. G. Mancini, A.O. Carbonara, and J.F. Heremans Immunochemical quantitation of antigens by single radial immunodiffusion Immunochemistry 2 1965 235 254
16. G.D. Maniero The influence of temperature and season on mitogen-induced proliferation of ground squirrel lymphocytes G. Heldmaier M. Klingensporer Life in the Cold 2000 Springer Berlin 493 503
17. G.D. Maniero Classical pathway serum complement activity throughout various stages of the annual cycle of a mammalian hibernator, the golden-mantled ground squirrel, Spermophilus lateralis Dev. Comp. Immunol. 26 2002 563 574
18. K. Mominoki, N. Nakagawa-Tosa, M. Morimatsu, B. Syuto, and M. Saito Haptoglobin in Carnivora: a unique molecular structure in bear, cat and dog haptoglobins Comp Biochem. Physiol., B 110 1995 785 789
19. K. Mominoki, E. Hohtola, M. Karjalainen, R. Hissa, M. Morimatsu, and M. Saito Seasonal variations of blood haptoglobin level of brown bears F. Geiser A.J. Hulbert S.C. Nicol Adaptations to the Cold 1996 University of New England Press Armidale 367 372
20. K. Mominoki, H. Tsuruga, M. Morimatsu, and M. Saito Seasonal variations of blood haptoglobin level of brown bears in Japan Comp. Biochem. Physiol, A 114 1996 349 353
21. M. Morimatsu, B. Syuto, N. Shimada, T. Fujinaga, S. Yamamoto, M. Saito, and M. Naiki Isolation and characterization of bovine haptoglobin from acute phase sera J. Biol. Chem. 266 1991 11833 11837
22. R.K. Murray, and G.E. Connell Elevation of serum haptoglobin in rabbits in response to experimental inflammation Nature 186 1960 86
23. R.A. Nelson, H.W. Wahner, J.D. Jones, R.D. Ellefson, and P.E. Zollman Metabolism of bear before, during and after winter sleep Am. J. Physiol. 224 1973 491 496
24. 2macroglobulin in wild black bears during hibernation Biochimie 85 2003 1027 1032
25. H.K. Srere, L.C. Wang, and S.L. Martin Central role for differential gene expression in mammalian hibernation Proc. Natl. Acad. Sci. U. S. A. 89 1992 7119 7123
26. 2Macroglobulin gene expression during hibernation in ground squirrels is independent of acute phase response Am. J. Physiol. 268 1995 R1501 R1512
27. 1antitrypsin-like genes in hibernating species of the squirrel family Gene 204 1997 127 132
28. H. Towbin, T. Staehelin, and J. Gordon Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications Proc. Natl. Acad. Sci. U. S. A. 76 1979 4350 4354
29. J. van Gool, H. van Vugt, M. Helle, and L.A. Aarden The relation among stress, adrenalin, interleukin 6 and acute phase proteins in the rat Clin. Immunol. Immunopathol. 57 1990 200 210
30. D. Zhou, A.W. Kusnecov, M.R. Shurin, M. DePaoli, and B.S. Rabin Exposure to physical and psychological stressors elevates plasma interleukin 6: relationship to the activation of hypothalamic-pituitary-adrenal axis Endocrinology 133 1993 2523 2530