Hypoxia silences the neural activities in the early phase of the phrenic neurogram of eupnea in the piglet

Journal of NeuroEngineering and Rehabilitation

Volumn 2, Issue , 2005, Pages

  Akay, Metin ^a  

^a Arizona State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BREATHING; FOURIER TRANSFORMATION; FREQUENCY ANALYSIS; HYPOXIA; NONHUMAN; PERINATAL PERIOD; SWINE; TIME SERIES ANALYSIS;

EID: 29244477904     PISSN: 17430003     EISSN: 17430003     Source Type: Journal    
DOI: 10.1186/1743-0003-2-32     Document Type: Article

References (31)

1. 2 sensitivity of cat phrenic neurogram during hypoxic respiratory depression. J Appl Physiol 1988, 65(2):7536-7543.
2. Melton JE, Chae LO, Neubauer JA, Edelman NH: Extracellular potassium homeostasis in the cat medulla during progressive brain hypoxia. J Appl Physiol 1991, 70(4):1477-1482.
3. Melton JE, Wasicko MJ, Neubauer JA, Edelman NH: Patterns of phrenic depression during progressive brain hypoxia. FASEB J 1988, 2(4):A510.
4. Neubauer JA, Melton JE, Edelman NH: Modulation of respiration during brain hypoxia (review). J Appl Physiol 1990, 68(2):441-451.
5. Neubauer JA, Simone A, Edelman NH: Role of brain lactic acidosis in hypoxic depression of respiration. J Appl Physiol 1988, 65(3):1324-1331.
6. Guntheroth WG, Kawabori I: Hypoxic apnea and gasping. J Clin Invest 1975, 56(6):1371-1377.
7. Lawson EE, Thatch BJ: Respiratory patterns during progressive asphyxia in newborn rabbits. J Appl Physiol 1977, 43:468-474.
8. Lumsden T: Observations on the respiratory centres. J Physiol 1923, 57:354-367.
9. Macefield G, Nail B: Phrenic and external intercostal motoneuron activity during progressive asphyxia. J Appl Physiol 1987, 63(4):1413-1420.
10. Davis PJ, Macefield G, Nail BS: Respiratory muscle activity during asphyxic apnoea and opisthotonus in the rabbit. Respir Physiol 1986, 65(3):285-294.
11. Macefield G, Nail B: Inspiratory augmentation during asphyxic hyperpnoea and gasping: proprioceptive influences. Respir Physiol 1986, 64(1):57-68.
12. Breckenridge CG, Hoff HE: Pontine and medullary regulation of respiration in the cat. Am J Physiol 1950, 160:385-394.
13. Lumsden T: Observations on the respiratory centres in the cat. J Physiol 1923, 57:153-160.
14. St John WM, Knuth KV: A characterization of the respiratory pattern of gasping. J Appl Physiol: Resp, Environ & Exercise Physiol 1981, 50(1):984-993.
15. St John WM, Zhou D, Fregosi RF: Expiratory neural activities in gasping. J Appl Physiol 1989, 66(1):223-231.
16. Zhou D, Wasicko MJ, Hu J, St John WM: Differing activities of medullary respiratory neurons in eupnea and gasping. J Appl Physiol 1991, 70(3):1265-1270.
17. St John WM, Bledsoe TA, Sokol HW: Identification of medullary loci critical for neurogenesis of gasping. J Appl Physiol: Resp, Environ & Exercise Physiol 1984, 56(4):1008-1019.
18. Cohen MI: Synchronization of discharge, spontaneous and evoked, between inspiratory neurons. Acta Neurobiol Exp 1973, 33(1):189-218.
19. Jacobi MS, Thach BT: Effect of maturation on spontaneous recovery from hypoxic apnea by gasping. J Appl Physiol 1989, 66(5):2384-2390.
20. Mitchell RA, Herbert DA: Synchronized high frequency synaptic potentials in medullary respiratory neurons. Brain Res 1974, 75(2):350-355.
21. Cohen MI, Feldman JL: Discharge properties of dorsal medullary inspiratory neurons: relation to pulmonary afferent and phrenic efferent discharge. J Neurophysiol 1984, 51(4):753-776.
22. Cohen MI, See WR, Christakos CN, Sica AL: High-frequency and medium-frequency components of different inspiratory nerve and their modification by various inputs. Brain Res 1987, 417(1):148-152.
23. Christakos CN, Cohen MI, See WR, Barnhardt R: Fast rhythms in the discharges of medullary inspiratory neurons. Brain Res 1988, 463(2):362-367.
24. Richardson CA, Mitchell RA: Power spectral analysis of inspiratory nerve activity in the decerebrate cat. Brain Res 1982, 233(2):317-336.
25. Akay M, Melton JE, Welkowitz W, Edelman NH, Neubauer JA: Autoregressive spectral analysis of phrenic neurogram during eupnea and gasping. J Appl Physiol 1996, 81(2):530-540.
26. Suthers GK, Henderson-Smart DJ, Read DJC: Postnatal changes in the rate of high frequency bursts of inspiratory activity in cats and dogs. Brain Res 1977, 132(3):537-540.
27. Cohen HL, Gootman PM, Steele AM, Eberle LP, Rao PP: Agerelated changes in power spectra of efferent phrenic activity in the piglet. Brain Res 1987, 426(1):179-182.
28. Webber CL: High-frequency oscillations within early and late phases of the phrenic neurogram. J Appl Physiol 1989, 66(2):886-893.
29. Akay M, Sekine M: The Effects of Maturation on Early and Late Phases of Phrenic Neurogram in Piglets during Maturation. IEEE Trans on Biomedical Engineering, IEEE Trans on Biomedical Engineering 2004, 51:1954-1959.
30. Akay M: Time Frequency and Wavelets in Biomedical Signal Processing New York: Wiley-IEEE Press; 1997.
31. Jacobi MS, Gershan WM, Thach BT: Mechanism of failure of recovery from hypoxic apnea by gaping in 17- to 23 day-old mice. J Appl Physiol 1991, 71(3):1098-1105.