Development of a virucidal cream containing the monoglyceride monocaprin

Pharmazie

Volumn 60, Issue 12, 2005, Pages 897-899

  Thorgeirsdóttir, Thórunn Ósk ^a   Hilmarsson, H ^a   Thormar, H ^a   Kristmundsdottir T ^a  

^a UNIVERSITY OF ICELAND   (Iceland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; MONOCAPRIN; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CREAM; DRUG DESIGN; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; MICROEMULSION;

ANTIVIRAL AGENTS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EMULSIONS; GLYCERIDES; HERPESVIRUS 1, HUMAN; OILS; WATER;

EID: 29244475393     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

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2. Bergsson G, Arnfinnsson J, Steingrímsson Ó, Thormar H (2002) Killing of Gram-positive cocci by fatty acids and monoglycerides. APMIS 109: 670-678.
3. Kristmundsdóttir T, Árnadóttir SG, Bergsson G, Thormar H (1999) Development and evaluation of microbicidal hydrogels containing monoglyceride as the active ingredient. J Pharm Sci 88: 1011-1015.
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5. Thorgeirsdóttir TO, Thormar H, Kristmundsdóttir T (2005) The influence of formulation variables on stability and microbicidal activity of the monoglyceride monocaprin. J Drug Del Sci Tech 15, 233-236.
6. Thorgeirsdóttir TO, Thormar H, Kristmundsdóttir T (2003) Effects of polysorbates on antiviral and antibacterial activity of monoglyceride in pharmaceutical formulations. Pharmazie 58: 286-287.
7. Thormar H, Isaacs CE, Brown HR, Barshatzky MR, Pessolano T (1987) Inactivation of enveloped viruses and killing of cells by fatty acids and monoglycerides. Antimicrob Agents Chemother 31: 27-31.
8. Thormar H, Bergsson G, Gunnarsson E, Georgsson G, Witvrouw M, Steingrímsson Ó, Clerq E De, Kristmundsdóttir T (1999) Hydrogels containing monocaprin have potent microbicidal activities against sexually transmitted viruses and bacteria in vitro. Sex Transm Inf 75: 181-185.
9. Whitley RJ, Roizman B (2001) Herpes simplex virus infections. Lancet 357: 1513-1518.