How should clinicians interpret results reflecting the effect of an intervention on composite end points: Should I dump this lump?

Evidence-Based Medicine

Volumn 10, Issue 6, 2005, Pages 162-163

  Montori, Victor M ^a   Busses, Jason W ^b   Miralda, Gaietà Permanyer ^c   Ferreira, Ignacio ^d   Guyatt, Gordon H ^b  

^a Mayo Clinic   (United States)

^b MCMASTER UNIVERSITY   (Canada)

^c HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

BIRTH INJURY; CESAREAN SECTION; CLINICAL PRACTICE; CLINICAL TRIAL; CONFIDENCE INTERVAL; DIETARY INTAKE; DYSTOCIA; EVIDENCE BASED MEDICINE; FRACTURE; FREQUENCY ANALYSIS; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN TREATMENT; MEDICAL DECISION MAKING; NERVE PARALYSIS; NEWBORN CARE; NEWBORN DISEASE; NOTE; OUTCOMES RESEARCH; PERINATAL DEATH; PERINATAL MORTALITY; PHYSICIAN; PREGNANCY DIABETES MELLITUS; RISK ASSESSMENT; RISK REDUCTION; SELF MONITORING;

EID: 29244473102     PISSN: 13565524     EISSN: None     Source Type: Journal    
DOI: 10.1136/ebm.10.6.162-a     Document Type: Note

References (5)

1. Crowther CA, Hiller JE, Moss JR, et al. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med 2005;352:2477-86.
2. Montori VM, Permanyer-Miralda G, Ferreira-Gonzalez I, et al. Validity of composite end points in clinical trials. BMJ 2005;330:594-6.
3. Greene MF, Solomon CG. Gestational diabetes mellitus - time to treat. N Engl J Med 2005;352:2544-6.
4. Brody SC, Harris R, Lohr K. Screening for gestational diabetes: a summary of the evidence for the U.S. Preventive Services Task Force. Obstet Gynecol 2003;101:380-92.
5. Landon MB, Thom E, Spong CY, et al. A planned randomized clinical trial of treatment for mild gestational diabetes mellitus. J Matern Fetal Neonatal Med 2002;11:226-31.