Diffuse expression of laminin γ2 chain in disseminating and infiltrating cancer cells indicates a highly malignant state in advanced tongue cancer

Oral Oncology

Volumn 42, Issue 1, 2006, Pages 72-75

  Kuratomi, Yuichiro ^a   Kumamoto, Mayuko ^b   Kidera, Kazuki ^a   Toh, Satoshi ^b   Masuda, Muneyuki ^b   Nakashima, Torahiko ^b   Inokuchi, Akira ^a  

^a SAGA UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Cell cell adhesiveness; Invasion; Laminin 2 chain; Prognosis; Tongue cancer

Indexed keywords

LAMININ; LAMININ GAMMA2; UNCLASSIFIED DRUG;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INFILTRATION; CANCER INVASION; CANCER PATIENT; CANCER SURVIVAL; CANCER TISSUE; CELL ADHESION; CELL DIFFERENTIATION; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; METASTASIS; NECK METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA; SURVIVAL RATE; SURVIVAL TIME; TONGUE CANCER;

EID: 29244441430     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2005.06.013     Document Type: Article

References (16)

1. S. Prince, and B.M. Bailey Squamous carcinoma of the tongue: review Br J Oral Maxillofac Surg 37 3 1999 164 174
2. S.C. Lim, S. Zhang, G. Ishii, Y. Endoh, K. Kodama, and S. Miyamoto Predictive markers for late cervical metastasis in stage I and II invasive squamous cell carcinoma of the oral tongue Clin Cancer Res 10 1 2004 166 172
3. T.M. Pimenta Amaral, A.R. Da Silva Freire, A.L. Carvalho, C.A. Pinto, and L.P. Kowalski Predictive factors of occult metastasis and prognosis of clinical stages I and II squamous cell carcinoma of the tongue and floor of the mouth Oral Oncol 40 8 2004 780 786
4. T. Asakage, T. Yokose, K. Mukai, S. Tsugane, Y. Tsubono, and M. Asai Tumor thickness predicts cervical metastasis in patients with stage I/II carcinoma of the tongue Cancer 82 8 1998 1443 1448
5. A.P. Yuen, K.Y. Lam, W.I. Wei, K.Y. Lam, C.M. Ho, and T.L. Chow A comparison of the prognostic significance of tumor diameter, length, width, thickness, area, volume, and clinicopathological features of oral tongue carcinoma Am J Surg 180 2 2000 139 143
6. M. Masuda, Y. Kuratomi, H. Shiratsuchi, T. Nakashima, K. Naonobu, and S. Komiyama Decreased CD44H expression in early-stage tongue carcinoma associates with late nodal metastases following interstitial brachytherapy Head Neck 22 7 2000 662 665
7. T. Yoshizaki, Y. Maruyama, H. Sato, and M. Furukawa Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma Int J Cancer 95 1 2001 44 50
8. N. Tanaka, T. Odajima, K. Ogi, T. Ikeda, and M. Satoh Expression of E-cadherin, alpha-catenin, and beta-catenin in the process of lymph node metastasis in oral squamous cell carcinoma Br J Cancer 89 3 2003 557 563
9. P. Tunggal, N. Smyth, M. Paulsson, and M.C. Ott Laminins: structure and genetic regulation Microsc Res Tech 51 3 2000 214 227
10. C. Pyke, J. Romer, P. Kallunki, L.R. Lund, E. Ralfkiaer, and K. Dano The γ2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers Am J Pathol 145 4 1994 782 791
11. J. Lohi Laminin-5 in the progression of carcinomas Int J Cancer 94 6 2001 763 767
12. G. Giannelli, and S. Antonaci Biological and clinical relevance of laminin-5 in cancer Clin Exp Metastasis 18 6 2000 439 443
13. S. Hirohashi, and Y. Kanai Cell adhesion system and human cancer morphogenesis Cancer Sci 94 7 2003 575 581
14. N. Tanaka, T. Odajima, K. Ogi, T. Ikeda, and M. Satoh Expression of E-cadherin, α-catenin, and β-catenin in the process of lymph node metastasis in oral squamous cell carcinoma Br J Cancer 89 3 2003 557 563
15. V. Chow, A.P. Yuen, K.Y. Lam, G.S. Tsao, W.K. Ho, and W.I. Wei A comparative study of the clinicopathological significance of E-cadherin and catenins (α, β, γ) expression in the surgical management of oral tongue carcinoma J Cancer Res Clin Oncol 127 1 2001 59 63
16. F. Hlubek, A. Jung, N. Kotzor, T. Kirchner, and T. Brabletz Expression of the invasion factor laminin γ2 in colorectal carcinomas is regulated by β-catenin Cancer Res. 61 22 2001 8089 8093