Influence of cellulose powder structure on moisture-induced degradation of acetylsalicylic acid

European Journal of Pharmaceutical Sciences

Volumn 27, Issue 2-3, 2006, Pages 220-225

  Mihranyan, A ^a   Stromme M ^b   Ek, R ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

ASA; Cellulose; Crystallinity index; Hydrolysis; Moisture sorption

Indexed keywords

ACETYLSALICYLIC ACID; CELLULOSE; SALICYLIC ACID;

ARTICLE; CRYSTAL STRUCTURE; DEGRADATION KINETICS; DRUG DEGRADATION; DRUG STABILITY; HUMIDITY; MOISTURE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TEMPERATURE; X RAY DIFFRACTION;

ASPIRIN; CELLULOSE; CRYSTALLOGRAPHY; DRUG STABILITY; EXCIPIENTS; HUMIDITY; MOLECULAR STRUCTURE; POWDERS; TIME FACTORS; WATER;

EID: 29244431947     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2005.10.002     Document Type: Article

References (12)

1. C. Ahlneck, and P. Lundgren Methods for the evaluation of solid-state stability and compatibility between drug and excipient Acta Pharm. Suec. 22 6 1985 305 314
2. C. Ahlneck, and G. Alderborn Solid-state stability of acetylsalicylic-acid in binary-mixtures with microcrystalline and microfine cellulose Acta Pharm. Suec. 25 1 1988 41 52
3. Wade, A., Weller, P.J. (Eds.), Handbook of Pharmaceutical Excipients, 2nd ed. Pharmaceutical Press, London, 1994, pp. 84-87.
4. F. Khan, and N. Pilpel An investigation of moisture sorption in microcrystalline cellulose using sorption isotherms and dielectric response Powder Tech. 50 1987 237 241
5. M. Landín, B. Perezmarcos, M. Casalderrey, R. Martinez-Pacheco, J.L. Gomez-Amoza, C. Souto, A. Concheiro, and R.C. Rowe Chemical-stability of acetylsalicylic-acid in tablets prepared with different commercial brands of dicalcium phosphate dihydrate Int. J. Pharm. 107 3 1994 247 249
6. A. Mihranyan, A. Piñas Llagostera, R. Karmhag, M. Strømme, and R. Ek Moisture sorption by cellulose powders of varying crystallinity Int. J. Pharm. 269 2 2004 433 442
7. A. Mihranyan, S.B. Andersson, and R. Ek Sorption of nicotine to cellulose powders Eur. J. Pharm. Sci. 22 4 2004 279 286
8. A. Mihranyan, and M. Strømme Capillary condensation of moisture in fractal pores of native cellulose powders Chem. Phys. Lett. 393 4-6 2004 389 392
9. M. Strømme, A. Mihranyan, R. Ek, and G.A. Niklasson Fractal dimension of cellulose powders analyzed by multilayer BET adsorption of water and nitrogen J. Phys. Chem. B 107 51 2003 14378 14382
10. C. Verlhac, J. Didier, and H. Chanzy Availability of surface hydroxyl groups in Valonia and bacterial cellulose J. Polym. Sci. Part A: Polym. Chem. 28 1990 1171 1177
11. E. Yonemochi, M. Matsumura, T. Oguchi, K. Yamamoto, and Y. Nakai Interactions of medicinals and porous powder - stability of aspirin in controlled pore glass solid dispersions Chem. Pharm. Bull. 39 4 1991 1027 1031
12. G. Zografi, and M.J. Kontny The interactions of water with cellulose- and starch-derived excipients Pharm. Res. 3 1986 187 194