Evaluation of endocrine disrupting activity of plasticizers in polyvinyl chloride tubes by estrogen receptor alpha binding assay

Journal of Artificial Organs

Volumn 8, Issue 4, 2005, Pages 252-256

  Ohashi, Atsushi ^a   Kotera, Hirohisa ^b   Hori, Hideo ^a   Hibiya, Makoto ^a   Watanabe, Koji ^a   Murakami, Kazutaka ^c   Hasegawa, Midori ^c   Tomita, Makoto ^c   Hiki, Yoshinobu ^c   Sugiyama, Satoshi ^c  

^a FUJITA HEALTH UNIVERSITY   (Japan)

^b KYOTO CITY HOSPITAL   (Japan)

^c FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

Di(2 ethylhexyl)phthalate; Endocrine disruptor; Estrogen receptor alpha; Extracorporeal circulation tube; Plasticizer free materials; Tris(2 ethylhexyl)trimellitate

Indexed keywords

ENDOCRINE DISRUPTOR; ESTROGEN RECEPTOR ALPHA; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PLASTICIZER; POLYVINYLCHLORIDE; SOYBEAN OIL;

ARTICLE; BINDING AFFINITY; BINDING ASSAY; BIOCOMPATIBILITY; CONTROLLED STUDY; ELUTION; EPOXIDATION; ESTROGEN ACTIVITY; EVALUATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NONHUMAN; PLASMA; PRIORITY JOURNAL; RECEPTOR BINDING;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COATED MATERIALS, BIOCOMPATIBLE; DIETHYLHEXYL PHTHALATE; ENDOCRINE SYSTEM; ESTROGEN RECEPTOR ALPHA; EXTRACORPOREAL CIRCULATION; HUMANS; PLASTICIZERS; POLYVINYL CHLORIDE;

EID: 29144510008     PISSN: 14347229     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10047-005-0307-y     Document Type: Article

References (11)

1. RJ Jaeger RJ Rubin 1970 Plasticizers from plastic devices: extraction, metabolism, and accumulation by biological systems Science 170 460 462
2. K Inoue H Okumura T Higuchi H Oka Y Yoshimura H Nakazawa 2002 Characterization of estrogenic compounds in medical polyvinyl chloride tubing by gas chromatography-mass spectrometry and estrogen receptor binding assay Clin Chim Acta 325 157 163
3. DK Agarwal WH Lawrence JE Turner J Autian 1989 Effects of parenteral di-(2-ethylhexyl)phthalate (DEHP) on gonadal biochemistry, pathology, and reproductive performance of mice J Toxicol Environ Health 26 39 59
4. TJ Gray SD Gangolli 1986 Aspects of the testicular toxicity of phthalate esters Environ Health Perspect 65 229 235
5. WW Huber B Grasl-Kraupp R Schulte-Hermann 1996 Hepatocarcinogenic potential of di(2-ethylhexyl)phthalate in rodents and its implications on human risk Crit Rev Toxicol 26 365 481
6. T Colborn D Dumanoski JP Myers 1996 Our stolen future Dutton New York
7. Center for Devices and Radiological Health, U.S. Food and Drug Administration (FDA). Safety assessment of di(2-ethylhexyl)phthalate (DEHP) released from PVC. Medical Devices, 2001
8. Organization of Economic Cooperation and Development (OECD). Third meeting of the validation management group for the screening and testing of endocrine disrupters (mammalian effects). ENV/JM/TG/EDTA. Paris: OECD, 2001
9. T Dine M Luyckx M Cazin C Brunet JC Cazin F Goudaliez 1991 Rapid determination by high-performance liquid chromatography of di-2-ethylhexyl phthalate in plasma stored in plastic bags Biomed Chromatogr 5 94 97
10. A Ohashi M Hibiya Y Nakagami M Kato H Yoshikawa T Toba H Kushimoto H Katsumata K Murakami M Hasegawa M Tomita H Hasegawa M Shikano S Kawashima 1999 High-performance membranes are useful in the removal of di-(2-ethylhexyl) phthalate eluted from blood circulating tubes J Jpn Soc Dial Ther 32 1291 1297
11. K Sawanishi T Iwasaki Y Shimahara E Ishikawa K Daijo M Hirose F Osako 1982 Kidney failure sexual dysfunction in male patients undergoing hemodialysis Nippon Rinsho 40 1377 1384