Transformation of revertant murine cells by 5-azacytidine results in rapid inhibition of lysyl oxidase expression

Acta Microbiologica et Immunologica Hungarica

Volumn 52, Issue 3-4, 2005, Pages 433-442

  Yeh, Tze Jou Annie ^a   Contente, Sara ^a   Friedman, Robert M ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Inhibition of lysyl oxidase expression; Transformation by 5 azacytidine

Indexed keywords

MURINAE;

EID: 29144496987     PISSN: 12178950     EISSN: 15882640     Source Type: Journal    
DOI: 10.1556/AMicr.52.2005.3-4.13     Document Type: Article

References (26)

1. Trackman, P. C., Bedell-Hogan, D., Tang, J., Kagan, H. M.: Post-translational glycosylation and proteolytic processing of a lysyl oxidase precursor. J Biol Chem 267, 8666-8671 (1992).
2. Cronshaw, A. D., Fothergill-Gilmore, L. A., Hulmes, D. J.: The proteolytic processing site of the precursor of lysyl oxidase. Biochem J 306, 279-284 (1995).
3. Panchenko, M. V., Stetler-Stevenson, W. G., Trubetskoy, O. V., Gacheru, S. N., Kagan, H. M.: Metalloproteinase activity secreted by fibrogenic cells in the processing of prolysyl oxidase. Potential role of procollagen C-proteinase. J Biol Chem 271, 7113-7119 (1996).
4. Uzel, M. I., Scott, I. C., Babakhanlou-Chase, H., Palamakumbura, A. H., Pappano, W. N., Hong, H. H., Greenspan, D. S., Trackman, P. C.: Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures. J Biol Chem 276, 22537-22543 (2001).
5. Giampuzzi, M., Botti, G., Cilli, M., Gusmano, R., Borel, A., Sommer, P., Di Donato, A.: Down-regulation of lysyl oxidase-induced tumorigenic transformation in NRK-49F cells characterized by constitutive activation of ras proto-oncogene. J Biol Chem 276, 29226-29232 (2001).
6. Contente, S., Kenyon, K., Rimoldi, D., Friedman, R. M.: Expression of gene rrg is associated with reversion of NIH 3T3 transformed by LTR-c-H-ras. Science 249, 796-798 (1990).
7. Kenyon, K., Contente, S., Trackman, P. C., Tang, J., Kagan, H. M., Friedman, R. M.: Lysyl oxidase and rrg messenger RNA. Science 253, 802 (1991).
8. Ren, C., Yang, G., Timme, T. L., Wheeler, T. M., Thompson, T. C.: Reduced lysyl oxidase messenger RNA levels in experimental and human prostate cancer. Cancer Res 58, 1285-1290 (1998).
9. Friedman, R. M., Yeh, A., Gutman, P., Contente, S., Kenyon, K.: Reversion by deletion of transforming oncogene following interferon-beta and retinoic acid treatment. J Interferon Cytokine Res 17, 647-651 (1997).
10. Samid, D., Chang, E. H., Friedman, R. M.: Biochemical correlates of phenotypic reversion in interferon-treated mouse cells transformed by a human oncogene. Biochem Biophys Res Commun 119, 21-28 (1984).
11. Kenyon, K., Modi, W. S., Contente, S., Friedman, R. M.: A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25. J Biol Chem 268, 18435-18437 (1993).
12. Saito, H., Papaconstantinou, J., Sato, H., Goldstein, S.: Regulation of a novel gene encoding a lysyl oxidase-related protein in cellular adhesion and senescence. J Biol Chem 272, 8157-8160 (1997).
13. Jang, W., Hua, A., Spilson, S. V., Miller, W., Roe, B. A., Meisler, M. H.: Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res 9, 53-61 (1999).
14. Maki, J. M., Kivirikko, K. I.: Cloning and characterization of a fourth human lysyl oxidase isoenzyme. Biochem J 355, 381-387 (2001).
15. Maki, J. M., Tikkanen, H., Kivirikko, K. I.: Cloning and characterization of a fifth human lysyl oxidase isoenzyme: the third member of the lysyl oxidase-related subfamily with four scavenger receptor cysteine-rich domains. Matrix Biol 20, 493-496 (2001).
16. Ito, H., Akiyama, H., Iguchi, H., Iyama, K., Miyamoto, M., Ohsawa, K., Nakamura, T.: Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage. J Biol Chem 276, 24023-24029 (2001).
17. Samid, D., Flessate, D. M., Friedman, R. M.: Interferon-induced revertants of ras-transformed cells: Resistance to transformation by specific oncogenes and retransformation by 5-azacytidine. Mol Cell Biol 7, 2196-2200 (1987).
18. Contente, S., Kenyon, K., Sriraman, P., Subramanyan, S., Friedman, R. M.: Epigenetic inhibition of lysyl oxidase transcription after transformation by ras oncogene. Mol Cell Biochem. 194, 79-91 (1999).
19. Csiszar, K.: Lysyl oxidases: a novel multifunctional amine oxidase family. Prog Nucleic Acid Res Mol Biol 70, 1-32 (2001).
20. Li, W., Nellaiappan, K., Strassmaier, T., Graham, L., Thomas, K. M., Kagan, H. M.: Localization and activity of lysyl oxidase within nuclei of fibrogenic cells. Proc Natl Acad Sci USA 94, 12817-12822 (1997).
21. Kagan, H. M., Williams, M. A., Calaman, S. D., Berkowitz, E. M.: Histone H1 is a substrate for lysyl oxidase and contains endogenous sodium borotritide-reducible residues. Biochem Biophys Res Commun 115, 186-192 (1983).
22. Giampuzzi, M., Botti, G., Di Duca, M., Arata, L., Ghiggeri, G., Gusmano, R., Ravazzolo, R., Di Donato, A.: Lysyl oxidase activates the transcription activity of human collagene III promoter. Possible involvement of Ku antigen. J Biol Chem 275, 36341-36349 (2000).
23. Giampuzzi, M., Oleggini, R., Di Donato, A.: Demonstration of in vitro interaction between tumor suppressor lysyl oxidase and histones H1 and H2: definition of the regions involved. Biochim Biophys Acta 1647, 245-251 (2003).
24. Palamakumbura, A. H., Jeay, S., Guo, Y., Pischon, N., Sommer, P., Sonenshein, G. E., Trackman, P. C.: The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. J Biol Chem 279, 40593-40600 (2004).
25. Tomkins, G. M., Thompson, E. B., Hayashi, S., Gelehrter, T., Granner, D., Peterkofsky, B.: Tyrosine transaminase induction in mammalian cells in tissue culture. Cold Spring Harb Symp Quant Biol 31, 349-360 (1966).
26. Cavalieri, R. L., Havell. E. A., Vilcek, J., Pestka, S.: Induction and decay of human fibroblast interferon mRNA. Proc Natl Acad Sci USA 74, 4415-4419 (1977).