Glucocorticoid inhibits the human pro-interleukin lβ gene (ILIB) by decreasing DNA binding of transactivators to the signal-responsive enhancer

Molecular Immunology

Volumn 43, Issue 7, 2006, Pages 773-782

  Waterman, Wayne R ^a   Xu, Li Lian ^b   Tetradis, Sotirios ^c   Motyckova, Gabriela ^d   Tsukada, Junichi ^e   Saito, Kazuyoshi ^e   Webb, Andrew C ^f   Robinson, Dwight R ^b   Auron, Philip E ^g  

^a PHILADELPHIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UCLA SCHOOL OF DENTISTRY   (United States)

^d HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^e UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^f WELLESLEY COLLEGE   (United States)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Enhancer promoter elements; Gene transcription; Glucocorticoid; Inflammation; Interleukin 1beta

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN DELTA; DEXAMETHASONE; DIMER; DNA; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; OROSOMUCOID; PROINTERLEUKIN 1BETA; PROTEIN PRECURSOR; STAT PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENHANCER REGION; GENE REPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; TRANSACTIVATION; TRANSCRIPTION REGULATION;

BINDING SITES; CCAAT-ENHANCER-BINDING PROTEIN-DELTA; CELLS, CULTURED; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DEXAMETHASONE; DNA; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; PROTEIN PRECURSORS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

ANIMALIA;

EID: 29144485740     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2005.07.003     Document Type: Article

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