Development and validation of an antigen-binding capture ELISA for native and putrescine-modified anti-tetanus F(ab′)2 fragments for the assessment of the cellular uptake and plasma kinetics of the antibodies

Journal of Immunological Methods

Volumn 307, Issue 1-2, 2005, Pages 82-95

  Welfringer, Frédéric ^a   D'Athis, Philippe ^b   Scherrmann, Jean Michel ^a   Hervé, Françoise ^c  

^a CNRS   (France)

^b DIJON UNIVERSITY HOSPITAL   (France)

^c HÔPITAL FERNAND WIDAL   (France)

Author keywords

Anti tetanus F(ab )2 fragments; Antigen binding capture ELISA; Assay validation; Cationization; Cellular uptake; Plasma kinetics

Indexed keywords

ALKALINE PHOSPHATASE; BALANCED SALT SOLUTION; BOVINE SERUM ALBUMIN; CARBOXYL GROUP; CATION; CYANAMIDE; DILUENT; IMMUNOGLOBULIN F(AB')2 FRAGMENT; POLYCLONAL ANTIBODY; PUTRESCINE; TETANUS ANTIBODY; TETANUS TOXOID;

ACCURACY; ACIDITY; ANIMAL EXPERIMENT; ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; BIOTINYLATION; CELL LYSATE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG STABILITY; DRUG UPTAKE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; LOW TEMPERATURE PROCEDURES; MALE; MICROTITER PLATE ASSAY; NONHUMAN; PLASMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; STORAGE; SUBSTITUTION REACTION; VALIDATION PROCESS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CALIBRATION; CATIONS; ENDOCYTOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HL-60 CELLS; HORSES; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; ISOELECTRIC FOCUSING; MALE; PUTRESCINE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; TETANUS TOXOID; TOXOIDS;

ANIMALIA; BOVINAE; EQUUS CABALLUS;

EID: 29144467716     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2005.09.015     Document Type: Article

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