Molecular heterogeneity of glucose-6-phosphate dehydrogenase deficiency in Jordan

Haematologica

Volumn 90, Issue 12, 2005, Pages 1693-1694

  Karadsheh, Naif S ^a,b,d   Moses, Linda ^c   Ismail, Said I ^b   Devaney, Joseph M ^c   Hoffman, Eric ^c  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b THE UNIVERSITY OF JORDAN   (Jordan)

^c CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF JORDAN   (Jordan)

Author keywords

Favism; G6PD deficiency; Jordan

Indexed keywords

GLUCOSE 6 PHOSPHATE DEHYDROGENASE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENETIC HETEROGENEITY; GENETIC SCREENING; GEOGRAPHIC DISTRIBUTION; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HUMAN; INCIDENCE; JORDAN; MALARIA; MALE; MUTATIONAL ANALYSIS; NEGRO; POPULATION GENETICS;

ADAPTATION, PHYSIOLOGICAL; ADULT; AFRICA; ETHNIC GROUPS; GENETIC HETEROGENEITY; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; HUMANS; JORDAN; MALARIA; MALE;

EID: 29144463200     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. th ed. New York. McGraw-Hill, 2000. p. 4517-53.
2. Samilchuk E, Al-Suliman I, Usanga E, Al Awadi S. G6PD mutations and UDP- glucuronosyltransferase promoters polymorphism among G6PD deficient Kuwaitis. Blood Cells Mol Dis 2003;31:201-5.
3. Karadsheh NS, Gelbart T, Schulten H-J, Efferth T, Awidi A. Relationship between molecular variants and clinical manifestions in twelve glucose-6-phosphate dehydrogenase-deficient patients in Jordan. Acta Haematol 2005;115:(In press).
4. Beutler E. Red Cell Metabolism: A Manual of Biochemical Methods. New York, Grone & Straton 1984.
5. Beutler E, Kuhl W, Gelbart T, Forman L. DNA sequence abnormalities of human glucose-6-phosphate dehydrogenase variants. J Biol Chem 1991;266:4145-50.
6. Usanga EA, Ameen R. Glucose-6-phosphate dehydrogenase deficiency in Kuwait, Syria, Egypt, Iran, Jordan and Lebanon. Hum Hered 2000;50:158-61.
7. Hirono K, Kawate K, Honda A, Fujii H, Miwa S. A single mutation 202G→A in the human glucose-6-phosphate dehydrogenase gene (G6PD) can cause acute hemolysis by itself. Blood 2002;99:1498.
8. Town M, Bautista JM, Mason PJ, Luzzatto L. Both mutations in G6PD A- are necessary to produce the G6PD deficient phenotype. Hum Mol Genet 1992;1:171-4.
9. Zara R, Pujades A, Rovira A, Saavedra R, Fernandez J, Aymerich M, et al. Two new mutations of the glucose-6-phosphate dehydrogenase associated with haemolytic anaemia: clinical, biochemical and molecular relationships. Br J Haematol 1997;98:578-82.
10. Flores C, Maca-Meyer N, Larruga JM, Cabrera V, Karadsheh N, Gonzales AM. Isolates in a corridor of migration: a high-resolution analysis of Y-chromosome variation in Jordan. J Hum Genet 2005;50:435-41.