Acquired factor XII deficiency in a woman with recurrent fetal loss: Working on a differential diagnosis in a single case

Journal of Translational Medicine

Volumn 3, Issue , 2005, Pages

  D'Uva, Maristella ^a   Strina, Ida ^a   Mollo, Antonio ^a   Ranieri, Antonio ^a   De Placido, Giuseppe ^a   Di Micco, Pierpaolo ^b,c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^c NONE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 12; CARDIOLIPIN ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LUPUS ANTICOAGULANT; PROTEIN ANTIBODY;

ADULT; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; BLOOD CLOTTING FACTOR 12 DEFICIENCY; CASE REPORT; CAUCASIAN; DIFFERENTIAL DIAGNOSIS; FEMALE; FETUS WASTAGE; HEMOSTASIS; HUMAN; PARTIAL THROMBOPLASTIN TIME; RECURRENT ABORTION; SCREENING; THROMBOPHILIA;

EID: 29144457477     PISSN: 14795876     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-3-43     Document Type: Article

References (21)

1. Di Micco P, D'Uva M, Strina I, Mollo A, Amato V, Niglio A, De Placido G. The role of d-dimer as first marker of thrombophilia in women affected by sterility: implications in pathophysiology and diagnosis of thrombophilia-induced sterility. J Transl Med 2004; 2:38
2. Brenner B, Sarig G, Weiner Z, Younis J, Blumenfeld Z, Lanir N. Thrombophilic polymorphisms are common in women with fetal loss without apparent cause. Thromb Haemost 1999; 82:6-9
3. Sanson BJ, Fierich PW, Simioni P, Zanardi S, Hilsman MV, Girolami A, ten Cate JW, Prins MH. The risk of abortion and stillbirth in antithrombin-, protein C, and protein S deficient women. Thromb Haemost 1996; 75:387-388
4. Grandone E, Margaglione M, Colaizzo D, d'Addedda M, Cappucci G, Vecchione G. Factor V Leiden is associated with repeated and recurrent unexplained fetal losses. Thromb Haemost 1997; 77: 822-824
5. Martinelli I, Taioli E, Cetin I, Marinoni A, Gerosa S, Villa MV, Bozzo M, Mannucci PM. Mutations in coagulation factors in women with unexplained late fetal loss. N Engl J Med 2000; 343:1015-1018
6. Brenner B. Inherited thrombophilia and pregnancy loss. Thromb Haemost 1994; 82:634-640
7. Dossenbach-Glaninger A, von Trotsenburg M, Krugluger W, Dossenbach MR, Oberkanins C, Huber J, Hompeier P. Elevated coagulation factor VIII and the risk for maternal early pregnancy loss. Thromb Haemost 2004; 91:694-699
8. Asherson RA, Cervera R. "Primary", "secondary" and other variants of antiphospholipid syndrome. Lupus 1994; 3:293-298
9. Noble LS, Kutteh WH, Lashey N, Franklin RD, Herrada J. Antiphospholipid antibodies associated with recurrent pregnancy loss: prospective, multicenter, controlled pilot study comparing treatment with low molecular weight heparin versus unfractioned heparin. Fertil Steril 2005; 83:684-690
10. Braulke I, Priggmayer M, Melloh P, Hinney B, Kostering H, Gunther H. Factor XII (Hageman) deficiency in women with abitual abortion: new subpopulation of recurrent aborters? Fertil Steril 1993; 53:98-101
11. Jones DW, Mackie IJ, Gallimore MJ, Winter M. Antibodies to factor XII and recurrent fetal loss in patients with the anti-antiphospholid syndrome. Br J Haematol 2001; 113:550-552
12. Jones DW, Gallimore MJ, Winter M. Recurrent abortion-antibodies to factor XII or decrease in factor XII levels? Fertil Steril 2001; 76:1288-1289
13. Jones DW, Gallimore MJ, Winter M. Antibodies to factor XII: a possible predictive marker for recurrent fetal loss. Immunobiology 2003; 207:43-46
14. Jones DW, Gallimore MJ, Harris SL, Winter M. Antibodies to factor XII associated to lupus anticoagulant. Thromb Haemost 1999; 81:387-390
15. Jaeger U, Kapiotis S, Pabinger I, Puchhammer E, Kyrle PA, Lechner K. Transient lupus anticoagulant associated with hypoprothrombinaemia and factor XII deficiency following adenovirus infection. Ann Hematol 1993;67: 95-99
16. Hathaway WE and Goodnight HS Jr. Contact factor deficiencies. In Disorders of hemostasis and thrombosis. A clinical guide. Edited by Hathaway WE and Goodnight HS Jr. New York: McGraw-Hill; 1993:147-154
17. Halbmayer WM, Mannhalter C, Feichtinger C, Rubi K, Fisher M. The prevalence of factor XII deficiency in 103 orally anticoagulated outpatients suffering from recurrent venous and/or arterial thromboembolism. Thromb Haemost 1992; 68: 285-290
18. Jones DW, Gallimore MJ, MacKie IJ, Harris SL, Winter M. Reduced factor XII levels in patients with antiphospholipid syndrome are associated with antibodies to factor XII. Br J Haematol 2000; 110:721-726
19. Chalkiadakis G, Kyriakou D, Oekonomaki D, Tsiaoussis J, Alexandrakis M, Vasilakis S, Kouroumalis E. Acquired inhibitors to the coagulation factor XII associated with liver disease. Am J Gatroenterol 1999; 94: 2551-2553
20. Yamada H, Kato EH, Kobashi G, Ebina Y, Shimada S, Morikawa M, Yamada T, Sakuragi N, Fujimoto S. Recurrent pregnancy loss: etiology of thrombophilia. Semin Thromb Haemost 2001; 27:121-129
21. Iinuma Y, Sugiura-Ogasawara M, Makino A, Ozaki Y, Suzumori N and Suzumori K. Coagulation factor XII activity, but not an associated genetic polymorphism (46C/T), is linked to recurrent miscarriage. Fertil Steril 2002; 77:353-356