Interaction between central-peripheral chemoreflexes and cerebro-cardiovascular control

Clinical Autonomic Research

Volumn 15, Issue 6, 2005, Pages 373-381

  Spicuzza, Lucia ^a   Porta, Cesare ^b   Bramanti, Alfina ^b   Maffeis, Mara ^b   Casucci, Gaia ^b   Casiraghi, Nadia ^b   Bernardi, Luciano ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

Baroreflex; Cerebral circulation; Chemoreflex; Hypercapnia; Hypoxia

Indexed keywords

CARBON DIOXIDE; OXYGEN;

ADULT; ARTICLE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BRAIN CIRCULATION; BRAIN FUNCTION; BREATHING MECHANICS; CARDIOVASCULAR FUNCTION; CENTRAL NERVOUS SYSTEM; CHEMORECEPTOR REFLEX; CONTROLLED STUDY; END TIDAL CARBON DIOXIDE TENSION; FEMALE; HEART FUNCTION; HUMAN; HUMAN EXPERIMENT; HYPERCAPNIA; HYPOXIA; LUNG FUNCTION TEST; LUNG MINUTE VOLUME; MALE; MIDDLE CEREBRAL ARTERY; NORMAL HUMAN; OXYGEN SATURATION; PERIPHERAL NERVOUS SYSTEM; PRESSORECEPTOR REFLEX; RESPIRATORY FUNCTION; RR INTERVAL; SYMPATHETIC TONE;

ADULT; ANOXIA; BAROREFLEX; BLOOD PRESSURE; CEREBROVASCULAR CIRCULATION; CHEMORECEPTORS; FEMALE; HEART RATE; HUMANS; HYPERCAPNIA; MALE; PULMONARY VENTILATION;

EID: 29144432076     PISSN: 09599851     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10286-005-0284-5     Document Type: Article

References (37)

1. Abboud FM, MD Thames (1984) Interaction of cardiovascular reflexes in the circulatory control. In: Handbook of Physiology, The cardiovascular System. Peripheral Circulation and Organ Blood Flow. sect 2, vol III, part 2. Am Physiol Soc, Bethesda, pp 675-753
2. Ainslie PN, Poulin MJ (2004) Ventilatory, cerebrovascular, and cardiovascular interactions in acute hypoxia:regulation by carbon dioxide. J Appl Physiol 97:149-159
3. Bernardi L, Gabutti A, Porta C, Spicuzza L (2001) Slow breathing reduces chemoreflex response to hypoxia and hypercapnia, and increases baroreflex sensitivity. J Hypertens 19:2221-2229
4. Bernardi L, Hilz M, Stemper B, Passino C, Welsch G, Axelrod FB (2003) Respiratory and cerebrovascular responses to hypoxia and hypercapnia in familial dysautonomia. Am J Respir Crit Care Med 167:141-149
5. Bernardi L, Spadacini G, Bellwon J, Hajric R, Roskamm H, Frey AW (1998) Effect of breathing rate on oxygen saturation and exercise performance in chronic heart failure. Lancet 351:1308-1311
6. Brian JE, Faraci FM, Heistad DD (1996) Recent insights into the regulation of cerebral circulation. Clin Exp Pharmacol Physiol 23:449-457
7. Bristow JD, Brown EB, Cunningham JDC, Goode RC, Howson MO, Sleight P (1971) The effects of hypercapnia, hypoxia and ventilation on the baroreflex regulation of the pulse interval. J Physiol 216:281-302
8. 2 and ventilation separately and together on the sensitivity and setting of the baroreceptor cardiodepressor reflex in man. J Physiol 243:401-425
9. Choi JY, Morris JC, Hsu CY (1998) Aging and cerebrovascular disease. Neurol Clin 16:687-711
10. Chugh SS, Chua TP, Coats AJ (1996) Peripheral chemoreflex in chronic heart failure: friend and foe. Am Heart J 132:900-904
11. Corne S, Webster K, Younes M (2003) Hypoxic respiratory response during acute stable hypocapnia. Am J Respir Crit Care Med 167:1193-1199
12. 2. Acta Physiol Scand 129:157-153
13. 2 before and after an 8-h exposure to hypoxia in humans. J Appl Physiol 90:1607-1614
14. Francis DA, Coats JS, Ponikowski P (2000) Chemoreflex-Baroreflex interactions in cardiovascular disease. In: Bradley TD, Floras JS (eds) Sleep Apnea. Implication in cardiovascular and cerebrovascular disease. Marcel Dekker, New York, pp 261-283
15. Gur AY, Bova I, Bornstein NM (1996) Is impaired cerebral vasomotor reactivity a predictive factor of stroke in asymptomatic patients? Stroke 27:2188-2190
16. Hackett PH, Roach RC (2001) High-altitude illness. N Engl J Med 345:107-114
17. Halliwill JR, Minson CT (2002) Effect of hypoxia on arterial baroreflex control of heart rate and muscle nerve activity in humans. J Appl Physiol 93:857-864
18. Heistad DD, Abboud FM, Mark AL, Schnid PG (1974) Interaction of baroreceptor and chemoreceptor reflexes: modulation of the chemoreceptor reflex by changes in baroreceptor activity. J Clin Invest 53:1226-1236
19. Imray CH, Brearey S, Clarke T, Hale D, Morgan J, Walsh S, Wright AD (2000) Cerebral oxygenation at high altitude and the response to carbon dioxide, hyperventilation and oxygen. The Birmingham Medical Research Expeditionary Society. Clin Sci (Lond) 98:159-164
20. Jensen JB, Wright AD, Lassen NA, Harvey TC, Winterborn MH, Raichle ME, Bradwell AR (1990) Cerebral blood flow in acute mountain sickness. J Appl Physiol 69:430-433
21. Jordan J, Shannon JR, Diedrich A, Black B, Costa F, Robertson D, Biaggioni I (2000) Interaction of carbon dioxide and sympathetic nervous system activity in the regulation of cerebral perfusions in humans. Hypertension 36:383-388
22. Kemmotsu O, Ueda M, Otsuka H, Yamamura T, Winter DC, Eckerle JS (1991) Arterial tonometry for noninvasive, continuous blood pressure monitoring during anesthesia. Anesthesiology 75:333-340
23. Kongo M, Yamamoto R, Kobayashi M, Nosaka S (1999) Hypoxia inhibits baroreflex vagal bradycardia via a central action in anaesthetized rats. Exp Physiol 84:47-56
24. 2 responsiveness in humans. J Physiol 551:609-616
25. Malliani A, Pagani M, Lombardi F, Cerutti S (1991) Cardiovascular neural regulation explored in the frequency domain. Circulation 84:482-492
26. Massik J, Jones MDJr, Miyabe M, Tang YL, Hudak ML, Koehler RC, Traystman RJ (1989) Hypercapnia and response of cerebral blood flow to hypoxia in newborn lambs. J Appl Physiol 66:1065-1070
27. Milic-Emili J (1975) Clinical methods for assessing the ventilatory response to carbon dioxide and hypoxia. N Engl J Med 10:864-865
28. Ponikowski P, Chua TP, Piepoli M, Ondusova D, Webb-Peploe K, Harrington D, Anker SD, Volterrani M, Colombo R, Mazzuero G, Giordano A, Coats AJ (1997) Augmented peripheral chemosensitivity as a potential input to baroreflex impairment and autonomic imbalance in chronic heart failure. Circulation 96:2586-2594
29. Ponikowski P, Francis DP, Piepoli MF, Davies LC, Chua TP, Davos CH, Florea V, Banasiak W, Poole-Wilson PA, Coats AJ, Anker SD (2001) Enhanced ventilatory response to exercise in patients with chronic heart failure and preserved exercise tolerance: marker of abnormal cardiorespiratory reflex control and predictor of poor prognosis. Circulation 102:967-972
30. Poulin MJ, Fatemian M, Tansley JG, O'Connor DF, Robbins PA (2002) Changes in cerebral blood flow during and after 48 h of both isocapnic and poikilocapnic hypoxia in humans. Exp Physiol 87:633-642
31. 2 by hypoxia. Stroke 3:286-289
32. Somers VK, Mark AL, Zavala DC, Abboud FM (1989) Influence of ventilation and hypocapnia on sympathetic responses to hypoxia in normal humans. J Appl Physiol 67:2095-2100
33. Somers VK, Mark AL, Zavala DC, Abboud FM (1989) Contrasting effects of hypoxia and hypercapnia on ventilation and sympathetic activity in humans. J Appl Physiol 67:2101-2106
34. Somers VK, Mark AL, Abboud FM (1991) Interaction of baroreceptor and chemoreceptor reflex control of sympathetic nerve activity in normal humans. J Clin Invest 87:1953-1975
35. Spicuzza L, Gabutti A, Porta A, Montana N, Bernardi L (2000) Yoga and chemoreflex response to hypoxia and hypercapnia. Lancet 356:1495-1496
36. Vetner SF, Priano LL, Rutheford JD, Manders WT (1980) Sympathetic regulation of the cerebral circulation by the carotid chemoreceptors reflex. Am J Physiol 238:H594-H598
37. Xie A, Skatrud JB, Puleo DS, Morgan BJ (2001) Exposure to hypoxia produces long-lasting sympathetic activation in humans. J Appl Physiol 91:1555-1562