A phase II trial of oral trimethylcolchicinic acid in patients with Hormone Refractory Prostate Cancer

Prostate Journal

Volumn 1, Issue 4, 1999, Pages 195-202

  Brockstein, Bruce E ^a,c   Shepard, Dale R ^a   Kugler, John W ^b   Fishkin, Paul A ^b   Arrieta, Rose ^a   Ratain, Mark J ^a   Vokes, Everett E ^a   Vogelzang, Nicholas J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b Oncology and Hematology Associates of Central Illinois   (United States)

^c MC 2115 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 28944449952     PISSN: 10955100     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1411.1999.14010.x     Document Type: Article

References (10)

1. American Cancer Society. (1999) Statistics. Available at: www.cancer.org/statistics/ cff99/selectedcancers.html#prostate
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4. Leiter J, Downing V, Harwell L, Shear MJ. (1952) Damage induced in sarcoma 37 with chemical agents: III. Colchicine derivatives related to trimethylcochicinic acid and to colchinol. J. Natl. Cancer Inst. 13: 379-392.
5. Lessner M, Johnson V, Loeb V, Larsen W. (1963) Primary clinical experience with trimethylcolchicinic acid ether d-tartrate (TMCA) in various malignancies. Cancer Chemother Rep. 27: 33-38.
6. Stolinsky DC, Jacobs EM, Bateman JR, et al. (1967) Clinical trial of trimethylcolchicinic acid methyl ether d-tartrate (TMCA; NSC 36354) in advanced cancer. Cancer Chemother. Rep. 51: 25-34.
7. Stolinsky DC, Jacobs EM, Braunwald J, Bateman JR. (1972) Further study of trimethylcolchinic acid, methyl ether d-tartrate (TMCA; NSC-36354) in patients with malignant melanoma. Cancer Chemother. Rep. 56: 263-265.
8. Stolinsky DC, Jacobs EM, Irwin LE, Pajak TF, Bateman JR. (1976) Effects of trimethylcolchinic acid, methyl ether d-tartrate (TMCA) on Hodgkin's and non-Hodgkin's lymphoma. Oncology 3: 151-153.
9. Stolinsky DC, Weiner JM, Bateman JR. (1980) Rotational therapy with a colchicine analog in chronic granulocyte leukemia. Oncology 37: 62-63.
10. Hu E, Ko R, Koda R, et al. (1990) Phase I toxicity and pharmacology study of trimethylcolchinic acid in patients with advanced malignancies. Cancer Chemother. Pharmacol. 26: 359-364.