A new efficient stereoselective debromination reaction with trialkylgermanium hydrides useful in the design of short synthetic routes to β-lactamase inhibitor prodrugs

Organic Process Research and Development

Volumn 9, Issue 6, 2005, Pages 792-799

  Norris, Timothy ^a   Dowdeswell, Christian ^b   Johnson, Natalka ^b   Daia, Dan ^b  

^a PFIZER INC   (United States)

^b SynProTec Limited   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 28944447641     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op050151s     Document Type: Article

References (16)

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11. 2EtN under the same conditions of hydrogenation, the ratio of 2 and 6 is in the range 9:1-13:1. This study will be reported in detail elsewhere. See also: Quallich, G. J.; Bordner, J.; Elliott, M. L.; Morrissey, P.; Volkmann, R. A.; Wroblewska-Adams, M. M. J. Org. Chem. 1990, 55, 367.
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