Successful treatment of a patient with chronic lymphocytic leukaemia (CLL) presenting with bony metastases with aggressive antibody and chemotherapy

Clinical and Laboratory Haematology

Volumn 27, Issue 6, 2005, Pages 405-408

  Narayan, H ^a   Bandyopadhyay, D ^a   Schmidt, K ^a   Chachlani, N ^a   Hughes, M ^a   Paneesha, S ^a   Rose, P ^a   Borg, Anton ^a  

^a WARWICK HOSPITAL   (United Kingdom)

Author keywords

Chronic lymphocytic leukaemia; Hypercalcaemia; Osteolytic lesions

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DOXORUBICIN; PAMIDRONIC ACID; PREDNISOLONE; PREDNISONE; RITUXIMAB; VINCRISTINE; VINCRISTINE SULFATE;

ADULT; ARTICLE; BONE EXAMINATION; BONE METASTASIS; CANCER CHEMOTHERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER REGRESSION; CANCER SCREENING; CASE REPORT; CHRONIC LYMPHATIC LEUKEMIA; FEMUR; HUMAN; HUMAN TISSUE; HYPERCALCEMIA; IMMUNOCYTOCHEMISTRY; LABORATORY TEST; LYMPHOCYTIC INFILTRATION; MALE; PRIORITY JOURNAL;

AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE NEOPLASMS; CYCLOPHOSPHAMIDE; DOXORUBICIN; FEMUR; HUMANS; HYPERCALCEMIA; LEUKEMIA, LYMPHOCYTIC, CHRONIC; MALE; PREDNISOLONE; REMISSION INDUCTION; VINCRISTINE;

EID: 28944439488     PISSN: 01419854     EISSN: 13652257     Source Type: Journal    
DOI: 10.1111/j.1365-2257.2005.00733.x     Document Type: Article

References (13)

1. Anzai S., Takayasu S., Fujiwara S., Tateyama M., Taira H. & Takashita M. (2002) Elevation of IL-6 in ATL patient with a pathological fracture. J Dermatol 29, 644-647.
2. Blanche P., Ribrag V., Dreyfus F. & Sicard D. (1995) Chronic lymphoid leukemia with bone involvement. Presse Med 24, 284.
3. Cayla J., Rondier J., Bonvarlet J.P. & Auriol M. (1981) Pseudotumoral osteolysis of the femur in chronic lymphoid leukemia. Rev Rhum Mal Osteoartic 48, 243-248.
4. Dunphy C.H., Oza Y.V. & Skelly M.E. (1997) Previously undescribed form of B-cell chronic lymphoid leukemia with IgA expression/secretion and lytic bone lesions. Am J Hematol 55, 208-211.
5. Hernandez Hernandez J.L., Olmos Martinez J.M., Figols Ladron De Guevara J., Riancho Moral J.A. & Gonzalez Macias J. (2000) Femoral osteolytic lesions with soft tissue tumors and hypercalcemia as presentation form of a B-cell lymphoma. An Med Interna 17, 264-266.
6. Kyasa M.J., Hazlett L., Parrish R.S., Schichman S.A. & Zent C.S. (2004) Veterans with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) have a markedly increased rate of second malignancy, which is the most common cause of death. Leuk Lymphoma 45, 507-513.
7. Littlewood T.J., Lydon A.P. & Barton C.J. (1990) Hypercalcemia and osteolytic lesions associated with chronic lymphatic leukemia (CLL). J Clin Pathol 43, 877.
8. Morgan L.A. (1995) Infiltrate of chronic lymphocytic leukemia appearing as a periapical radiolucent lesion. J Endod 21, 475-478.
9. Robak T., Kasznicki M., Bartkowiak J., Kordek R., Wawrzyniak E. & Blonski J.Z. (2001) Richter's syndrome following cladribine therapy for chronic lymphocytic leukemia first manifested as pathologic fracture of the femur. Leuk Lymphoma 42, 789-796.
10. Rossi J.F., Chappard D., Marcelli C., Laplante J., Commes T., Baldet P., Janbon C., Jourdan J., Alexandre C. & Bataille R. (1990) Micro-osteoclast resorption as a characteristic feature of B-cell malignancies other than multiple myeloma. Br J Haematol 76, 469-475.
11. Van De Casteele M., Verhoef G.E., Demuynck H., Zachee P. & Boogaerts M.A. (1994) Hypercalcemia, monoclonal protein, and osteolytic bone lesions in chronic Iymphocytic leukemia. Ann Hematol 69, 79-80.
12. Vlasveld L.T., Pauwels P., Ermens A.A., Aarnoudse W.H., Ooms H.W. & Haak H.R. (1999) Parathyroid hormone-related protein (PTH-rP)-associated hypercalcemia in a patient with an atypical chronic Iymphocytic leukemia. Neth J Med 54, 21-26.
13. Wright G.W., Wiesenfeld D. & Seymour J.F. (1997) Bilateral fracture of the mandible in chronic lymphocytic leukaemia. Case report. Aust Dent J 42, 20-24.