New presenilin 1 mutation with Alzheimer disease and Lewy bodies

Archives of Neurology

Volumn 62, Issue 12, 2005, Pages 1808-

  Rosenberg, Roger N ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOID NEUROPATHY; EDITORIAL; GENE MUTATION; GENETIC ANALYSIS; GENOMICS; HUMAN; LEWY BODY; MOLECULAR DYNAMICS; NEUROPATHOLOGY; PATHOGENESIS; PRIORITY JOURNAL;

ALPHA-SYNUCLEIN; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LEWY BODIES; MEMBRANE PROTEINS; MUTATION; NEUROFIBRILLARY TANGLES; PEPTIDE FRAGMENTS; PRESENILIN-1; SENILE PLAQUES;

EID: 28944439112     PISSN: 00039942     EISSN: 15383687     Source Type: Journal    
DOI: 10.1001/archneur.62.12.1808     Document Type: Editorial

References (4)

1. Rosenberg RN. The molecular and genetic basis of Alzheimer disease: the end of the beginning: the 2000 Wartenberg Lecture. Neurology. 2000;54:2045-2054.
2. Revesz T, McLaughlin JL, Rossor MN, Lantos PL. The pathology of familial Alzheimer's disease with Lewy bodies. J Neural Transm Suppl. 1997;51:121-135.
3. Lippa CF, Fujiwara H, Mann DM, et al. Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. Am J Pathol. 1998;153:1365-1370.
4. Snider BJ, Norton J, Coats MA, et al. Novel presenilin 1 mutation (S170F) causing Alzheimer disease with Lewy bodies in the third decade of life. Arch Neurol. 2005;62:1821-1830.