Efficacy and safety of oxymorphone immediate release for the treatment of mild to moderate pain after ambulatory orthopedic surgery: Results of a randomized, double-blind, placebo-controlled trial

Archives of Physical Medicine and Rehabilitation

Volumn 86, Issue 12, 2005, Pages 2284-2289

  Gimbel, Joseph S ^a   Walker, Dean ^b   Ma, Tina ^c   Ahdieh, Harry ^c  

^a Arizona Research Center   (United States)

^b Jean Brown Associates Inc   (United States)

^c ENDO PHARMACEUTICALS INC   (United States)

Author keywords

Analgesia; Oxymorphone; Pain, postoperative; Rehabilitation

Indexed keywords

ANALGESIC AGENT; OXYMORPHONE; PLACEBO;

ADULT; AMBULATORY SURGERY; ANALGESIA; ANALGESIC ACTIVITY; ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG RELEASE; DRUG SAFETY; ERROR; FEMALE; HEADACHE; HUMAN; KNEE ARTHROSCOPY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; OUTPATIENT; PAIN ASSESSMENT; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; VOMITING;

ADULT; AMBULATORY SURGICAL PROCEDURES; ANALGESICS, OPIOID; ANALYSIS OF VARIANCE; ARTHROSCOPY; DOUBLE-BLIND METHOD; FEMALE; HUMANS; KNEE; LEAST-SQUARES ANALYSIS; MALE; OXYMORPHONE; PAIN, POSTOPERATIVE; SAFETY;

EID: 28844473848     PISSN: 00039993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apmr.2005.07.303     Document Type: Article

References (13)

1. J. Stephens, B. Laskin, C. Pashos, B. Pena, J. Wong The burden of acute postoperative pain and the potential role of the COX-2-specific inhibitors Rheumatology (Oxford) 42 Suppl 3 2003 40 52
2. J.L. Apfelbaum, C. Chen, S.S. Mehta, T.J. Gan Postoperative pain experience results from a national survey suggest postoperative pain continues to be undermanaged Anesth Analg 97 2003 534 540
3. S.J. Dolin, J.N. Cashman, J.M. Bland Effectiveness of acute postoperative pain management: I. Evidence from published data Br J Anaesth 89 2002 409 423
4. D. Kamming, F. Chung, D. Williams, B.M. McGrath, B. Curti Pain management in ambulatory surgery J Perianesth Nurs 19 2004 174 182
5. American Academy of Pain Medicine and American Pain Society The use of opioids for the treatment of chronic pain 1997 AAPM, APS Glenview
6. R.S. Sinatra, N.H. Hyde, D.M. Harrison Oxymorphone revisited Semin Anesth 7 1988 209 215
7. J. Gimbel, H. Ahdieh The efficacy and safety of oral immediate-release oxymorphone for postsurgical pain Anesth Analg 99 2004 1472 1477
8. L.A. Rosseland, A. Stubhaug, F. Grevbo, O. Reikeras, H. Breivik Effective pain relief from intra-articular saline with or without morphine 2 mg in patients with moderate-to-severe pain after knee arthroscopy a randomized, double-blind controlled clinical study Acta Anaesthesiol Scand 47 2003 732 738
9. J. Toivonen, V.M. Pitko, P.H. Rosenberg Comparison between intra-articular bupivacaine with epinephrine and epinephrine alone on short-term and long-term pain after knee arthroscopic surgery under general anesthesia in day-surgery patients Acta Anaesthesiol Scand 46 2002 435 440
10. J.E. Lawless Statistical models and methods for lifetime data 1982 John Wiley & Sons New York
11. M. Kizilkaya, O.S. Yildirim, N. Dogan, H. Kursad, A. Okur Analgesic effects of intraarticular sufentanil and sufentanil plus methylprednisolone after arthroscopic knee surgery Anesth Analg 98 2004 1062 1065
12. J. Calmet, C. Esteve, S. Boada, J. Gine Analgesic effect of intra-articular ketorolac in knee arthroscopy comparison of morphine and bupivacaine Knee Surg Sports Traumatol Arthrosc 12 2004 552 555
13. H. Ahdieh, T. Ma, N. Babul, D. Lee Efficacy of oxymorphone extended release in postsurgical pain a randomized clinical trial in knee arthroplasty J Clin Pharmacol 44 2004 767 776