Effect of N-acetyl cysteine on Helicobacter pylori

Southern Medical Journal

Volumn 98, Issue 11, 2005, Pages 1095-1097

  Gurbuz, Ahmet Kemal ^a   Ozel, A Melih ^a   Ozturk, Ramazan ^a   Yildirim, Sukru ^a   Yazgan, Yusuf ^a   Demirturk, Levent ^a  

^a GATA HAYDARPASA TRAINING HOSPITAL   (Turkey)

Author keywords

Eradication therapy; Helicobacter pylori; N acetyl cysteine

Indexed keywords

ACETYLCYSTEINE; CLARITHROMYCIN; LANSOPRAZOLE;

ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG POTENTIATION; FEMALE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; NONHUMAN; SMOKING; STATISTICAL ANALYSIS; TASTE DISORDER;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ACETYLCYSTEINE; ANTI-BACTERIAL AGENTS; CLARITHROMYCIN; DRUG THERAPY, COMBINATION; EXPECTORANTS; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; OMEPRAZOLE; PROTON PUMPS; STOMACH DISEASES;

EID: 28844465314     PISSN: 00384348     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.smj.0000182486.39913.da     Document Type: Article

References (17)

1. Bechi P, Balzi M, Becciolini A, et al. Helicobacter pylori and cell proliferationof the gastric mucosa: possible implications for gastric carcinogenesis. Am J Gastroenterol 1996;91:271-276.
2. Kuipers EJ, Uyterlinde AM, Pena AS, et al. Long-term sequelae of Helicobacter pylori gastritis. Lancet 1995;345:1525-1528.
3. Marshall BJ. Helicobacter pylori: the etiologic agent for peptic ulcer. JAMA 1995;274:1064-1066.
4. Valle J, Kekki M, Sipponen P, et al. Long-term course and consequences of Helicobacter pylori gastritis: results of a32-year follow-up study. Scand J Gastroenterol 1996;31:546-550.
5. Rauws EA, Tytgat GN. Cure of duodenal ulcer associated with eradication of Helicobacter pylori. Lancet 1990;335:1233-1235.
6. Graham DY, Lew GM, Klein PD, et al. Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer: a randomized, controlled study. Ann Intern Med 1992;116:705-708.
7. Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med 2002;347:1175-1186.
8. Millman M, Goodman AH, Goldstein IM, et al. Treatment of a patient with chronic bronchial asthma with many bronchoscopies and lavage using acetylcysteine: a case report. J Asthma 1985;22:13-35.
9. Hazell SL, Lee A, Brady L, et al. Campylobacter pyloridis and gastritis: association with intercellular spaces and adaptation to an environment of mucus as important factors in colonization of the gastric epithelium. J Infect Dis 1986;153:658-663.
10. Demirturk L, Yazgan Y, Tarcin O, et al. Does N-acetyl cysteine affect the sensitivity and specificity of Helicobacter pylori stool antigen test? Helicobacter 2003;8:120-123.
11. Gotoh A, Akamatsu T, Shimizu et al. Additive effect of pronase on the efficacy of eradication therapy against Helicobacter pylori. Helicobacter 2002;7:183-191.
12. Zala G, Flury R, Wust J, et al. Omeprazole/amoxicillin: improved eradication of Helicobacter pylori in smokers because of N-acetylcysteine [in German]. Schweiz Med Wochenschr 1994;124:1391-1397.
13. Matthews GM, Kritas S, Tivey D, et al. N-acetylcysteine reduces mucosal glutathione and the inflammatory response in Helicobacter pylori infected mice. Helicobacter 2003;8:374.
14. Sherwood PV, Wibawa JID, Atherton JC, et al. Impact of acid secretion, gastritis, and mucus thickness on gastric transfer of antibiotics in rats. Gut 2002;51:490-95.
15. Böttcher W, Golanska EM, Kauffman GL Jr. N-acetyl-cysteine affords gastric mucosal protection while reducing gel mucus thickness. Surg Forum 1982;33:164-166.
16. Henagan JM, Smith GS, Miller TA, et al. N-acetyl-cysteine and prostaglandin: comparable protection against experimental ethanol injury in the stomach independent of mucus thickness. Ann Surg 1986;204:698-704.
17. Misawa M, Inamura N. In vitro evaluation of mucolytic activities of some expectorants using porcine gastric mucin. Jpn J Pharmacol 1988;92:263-270.