A 15-year-old girl with a spindle cell carcinoma of the parotid gland. A diagnostic challenge solved by immunohistochemistry and cytogenetic analysis

Acta Oto-Laryngologica

Volumn 126, Issue 1, 2006, Pages 104-107

  Brunings, Jan W ^a   Driessen, Ann ^a   De Jong, Jos M A ^a   Manni, Johannes J ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cytogenetics; Immunohistochemistry; Parotid gland; Spindle cell

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; CYTOKERATIN; DOXORUBICIN; EPITHELIAL MEMBRANE ANTIGEN; IFOSFAMIDE; VIMENTIN;

ADOLESCENT; CANCER DIAGNOSIS; CANCER MORTALITY; CANCER RADIOTHERAPY; CASE REPORT; CHROMOSOME ANALYSIS; CONFERENCE PAPER; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAXILLA; MEDICAL LITERATURE; METASTASIS; NECK DISSECTION; PAROTID GLAND; PAROTID GLAND CARCINOMA; PAROTIDECTOMY; PRIORITY JOURNAL; SPINDLE CELL CARCINOMA; UPPER RESPIRATORY TRACT;

ADOLESCENT; CARCINOMA; CYTOGENETIC ANALYSIS; DIAGNOSIS, DIFFERENTIAL; FATAL OUTCOME; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; NECK DISSECTION; PAROTID GLAND; PAROTID NEOPLASMS;

EID: 28844461338     PISSN: 00016489     EISSN: None     Source Type: Journal    
DOI: 10.1080/00016480510038545     Document Type: Conference Paper

References (18)

1. Kane WJ, McGaffrey TV, Olsen KD, Lewis JE. Primary parotid malignancies: a clinical and pathologic review. Arch Otolaryngol Head Neck Surg 1991;117:307-15.
2. Krolls SO, Trodahl JN, Boyers RC. Salivary gland lesions in children: a survey of 430 cases. Cancer 1972;30:459-69.
3. Thompson LDR, Wieneke JA, Miettinen M, Heffner DK. Spindle cell (sarcomatoid) carcinomas of the larynx. A clinicopathologic study of 187 cases. Am J Surg Pathol 2002;26:153-70.
4. Weidner N. Sarcomatoid carcinoma of the upper aerodigestive tract. Semin Diagn Pathol 1987;4:157-68.
5. Gnepp DR. Malignant mixed tumors of the salivary glands: a review. Pathol Annu 1993;28:279-328.
6. Leventon GS, Evans HL. Sarcomatoid squamous cell carcinoma of the mucous membranes of the head and neck: a clinicopathologic study of 20 cases. Cancer 1981; 48:994-1003.
7. Potsic WP, Raney FB Jr, Buck BE, Fischer SW. Juvenile spindle cell carcinoma. Otolaryngol Head Neck Surg 1979;87:573-7.
8. Anonsen C, Dobie RA, Hoekema D, Huang TW, Gown AM. Carcinosarcoma of the floor of mouth. J Otolaryngol 1985;14:215-20.
9. Zarbo RJ, Crissman JD, Venkat H, Weiss MA. Spindle-cell carcinoma of the upper aerodigestive tract mucosa. An immunohistologic and ultrastructural study of 18 biphasic tumors and comparison with seven monophasic spindle-cell tumors. Am J Surg Pathol 1986;10:741-53.
10. Stewart CJ, MacKenzie K, McGarry GW, Mowat A. Fine-needle aspiration cytology of salivary gland: a review of 341 cases. Diagn Cytopathol 2000;22:139-46.
11. Stanley MW. Selected problems in fine needle aspiration of head and neck masses. Mod Pathol 2002;15:342-50.
12. Batsakis JG, Suarez P. Sarcomatoid carcinomas of the upper aerodigestive tracts. Adv Anat Pathol 2000;7:282-93.
13. Meijer JWR, Ramaekers FCS, Manni JJ, Slooff JJL, Aldeweireldt J, Vooys GP. Intermediate filament proteins in spindle cell carcinoma of the larynx and tongue. Acta Otolaryngol (Stockh) 1988;106:306-13.
14. Guarino M. Epithelial-to-mesenchymal change of differentiation. From embryogenetic mechanisms to pathological patterns. Histol Histopathol 1995;10:171-84.
15. Azumi N, Battifora H. The distribution of vimentin and keratin epithelial and nonepithelial neoplasms. A comprehensive immunohistochemical study on formalin- and alcohol-fixed tumors. Am J Clin Pathol 1987;88:286-96.
16. Weiss SW, Goldblum JR. Malignant soft tissue tumors of uncertain type. In: Enzinger and Weiss's soft tissue tumors, 4th ed. Mosby; 2001. p. 1483-571.
17. Pruszczynski M, Manni JJ, Smedts F. Endolaryngeal synovial sarcoma: case report with immunohistochemical studies. Head Neck 1989;11:76-80.
18. Sreekantaiah C, Ladanyi M, Rodriguez E, Chaganti RSK. Chromosomal aberrations in soft tissue tumors: relevance to diagnosis, classification and molecular mechanisms. Am J Pathol 1994;144:1121-34.