Comparison of (+)- and (-)-hemipalmitoylcarnitinium as inhibitors of hepatic mitochondrial carnitine palmitoyltransferases in diabetic rats.

Medicinal chemistry

Volumn 1, Issue 5, 2005, Pages 445-453

  Savle, Prashant S ^a   Neptune, Nicole E ^a   Yang, Yanyan ^a   Rouden, Jacques H ^a   Kite, Brett L ^a   Sugandhi, Eko W ^a   Macri, Richard V ^a   Kashfi, Khosrow ^a   Gandour, Richard D ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE; DRUG DERIVATIVE; HEMIPALMITOYLCARNITINIUM; PALMITOYLCARNITINE; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BINDING SITE; CHEMISTRY; COMPARATIVE STUDY; CONFORMATION; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; INTRACELLULAR MEMBRANE; LIVER MITOCHONDRION; MALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; BINDING SITES; CARNITINE O-PALMITOYLTRANSFERASE; COMPARATIVE STUDY; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; INTRACELLULAR MEMBRANES; MALE; MITOCHONDRIA, LIVER; MOLECULAR CONFORMATION; PALMITOYLCARNITINE; RATS; RATS, SPRAGUE-DAWLEY; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 28844446368     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/1573406054864115     Document Type: Article

References (0)