Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography-tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 829, Issue 1-2, 2005, Pages 123-135

  Catz, Paul ^a   Shinn, Walter ^a   Kapetanovic, Izet M ^b   Kim, Hyuntae ^c   Kim, Moonsun ^c   Jacobson, Elaine L ^c   Jacobson, Myron K ^c   Green, Carol E ^a  

^a SRI INTERNATIONAL   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

Cancer chemoprevention; LC MS MS; Myristyl nicotinate; Nicotinamide; Nicotinic acid; Plasma

Indexed keywords

BIOASSAY; CARBOXYLIC ACIDS; ESTERS; ISOTOPES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; TUMORS;

CANCER CHEMOPREVENTION; LC-MS/MS; MYRISTYL NICOTINATE; NICOTINAMIDE; NICOTINIC ACID; PLASMA;

DRUG PRODUCTS;

2 BUTANONE; DRUG METABOLITE; MYRISTYL NICOTINATE; NIA 114; NICOTINAMIDE; NICOTINIC ACID; NICOTINIC ACID DERIVATIVE; SOLVENT; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BLOOD CHEMISTRY; CHEMOPROPHYLAXIS; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DEVICE; DOG; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; HUMAN; HUMAN TISSUE; LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; POSITIVE ION ELECTROSPRAY; PRIORITY JOURNAL; QUALITY CONTROL; RABBIT; RAT; REPRODUCIBILITY; ROOM TEMPERATURE; TANDEM MASS SPECTROMETRY; TEMPERATURE SENSITIVITY;

ANIMALS; BUTANONES; CHROMATOGRAPHY, LIQUID; NIACIN; NIACINAMIDE; RABBITS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

ANIMALIA; CANIS FAMILIARIS; NIA; ORYCTOLAGUS CUNICULUS;

EID: 28844436909     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.10.003     Document Type: Article

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