Understanding heme transport

New England Journal of Medicine

Volumn 353, Issue 23, 2005, Pages 2508-2509

  Andrews, Nancy C ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; DNA; HEME CARRIER PROTEIN 1; HEME OXYGENASE; HEMOPEXIN; IRON; PROTEIN INHIBITOR; PROTOPORPHYRIN ZINC; UNCLASSIFIED DRUG;

APICAL MEMBRANE; CELLULAR DISTRIBUTION; DISEASE EXACERBATION; DISEASE SEVERITY; DNA MODIFICATION; GENE MUTATION; HEME SYNTHESIS; HEMOCHROMATOSIS; HUMAN; INTESTINE ABSORPTION; INTESTINE CELL; IRON OVERLOAD; IRON TRANSPORT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SHORT SURVEY; STRUCTURAL HOMOLOGY; THREE DIMENSIONAL IMAGING;

DUODENUM; HEME; HEMOCHROMATOSIS; HUMANS; INTESTINAL ABSORPTION; IRON; MEMBRANE TRANSPORT PROTEINS; MUTATION;

EID: 28844433091     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcibr053987     Document Type: Short Survey

References (5)

1. Hentze MW, Muckenthaler MU, Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell 2004;117:285-97.
2. Shayeghi M, Latunde-Dada GO, Oakhill JS, et al. Identification of an intestinal heme transporter. Cell 2005;122:789-801.
3. Raffin SB, Woo CH, Roost KT, Price DC, Schmid R. Intestinal absorption of hemoglobin iron-heme cleavage by mucosal heme oxygenase. J Clin Invest 1974;54:1344-52.
4. Krishnamurthy P, Ross DD, Nakanishi T, et al. The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. J Biol Chem 2004;279:24218-25.
5. Quigley JG, Yang Z, Worthington MT, et al. Identification of a human heme exporter that is essential for erythropoiesis. Cell 2004;118:757-66.