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28744455764
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Acetylcholinesterase
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A. Meister John Wiley & Sons New York
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T.L. Rosenberry Acetylcholinesterase A. Meister Advances in Enzymology 1975 John Wiley & Sons New York 43
-
(1975)
Advances in Enzymology
-
-
Rosenberry, T.L.1
-
2
-
-
0025778840
-
Atomic structure of acetylcholinesterase from Torpedo californica: A prototypic acetylcholine-binding protein
-
J.L. Sussman, M. Harel, F. Frolow, C. Oefner, A. Goldman, L. Toker, and I. Silman Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein Science 253 1991 872 879
-
(1991)
Science
, vol.253
, pp. 872-879
-
-
Sussman, J.L.1
Harel, M.2
Frolow, F.3
Oefner, C.4
Goldman, A.5
Toker, L.6
Silman, I.7
-
3
-
-
0344316487
-
-
A. Shafferman B. Velan Plenum Press New York
-
I. Schalk, L. Ehret-Sabatier, F. Bouet, M. Goeldner, and C. Hirth A. Shafferman B. Velan Multidisciplinary Approaches to Cholinesterase Functions 1992 Plenum Press New York 117 120
-
(1992)
Multidisciplinary Approaches to Cholinesterase Functions
, pp. 117-120
-
-
Schalk, I.1
Ehret-Sabatier, L.2
Bouet, F.3
Goeldner, M.4
Hirth, C.5
-
4
-
-
0027517144
-
Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors
-
Z. Radic, N.A. Pickering, D.C. Vellom, S. Camp, and P. Taylor Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors Biochemistry 32 1993 12074 12084
-
(1993)
Biochemistry
, vol.32
, pp. 12074-12084
-
-
Radic, Z.1
Pickering, N.A.2
Vellom, D.C.3
Camp, S.4
Taylor, P.5
-
5
-
-
0028270692
-
Acetylcholinesterase peripheral anionic site degeneracy conferred by amino acid arrays sharing a common core
-
D. Barak, C. Kronman, A. Ordentlich, N. Ariel, A. Bromberg, D. Marcus, A. Lazar, B. Velan, and A. Shafferman Acetylcholinesterase peripheral anionic site degeneracy conferred by amino acid arrays sharing a common core J. Biol. Chem. 269 1994 6296 6305
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6296-6305
-
-
Barak, D.1
Kronman, C.2
Ordentlich, A.3
Ariel, N.4
Bromberg, A.5
Marcus, D.6
Lazar, A.7
Velan, B.8
Shafferman, A.9
-
6
-
-
0016823110
-
Interaction of fluorescence probes with acetylcholinesterase. the site and specificity of propidium binding
-
P. Taylor, and S. Lappi Interaction of fluorescence probes with acetylcholinesterase. The site and specificity of propidium binding Biochemistry 14 1975 1989 1997
-
(1975)
Biochemistry
, vol.14
, pp. 1989-1997
-
-
Taylor, P.1
Lappi, S.2
-
7
-
-
0021737985
-
Fasciculins, anticholinesterase toxins from the venom of the green mamba Dendroaspis angusticeps
-
E. Karlsson, P.M. Mbugua, and D. Rodriguez-Ithurralde Fasciculins, anticholinesterase toxins from the venom of the green mamba Dendroaspis angusticeps J. Physiol. (Paris) 79 1984 232 240
-
(1984)
J. Physiol. (Paris)
, vol.79
, pp. 232-240
-
-
Karlsson, E.1
Mbugua, P.M.2
Rodriguez-Ithurralde, D.3
-
9
-
-
0027368530
-
Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase
-
M. Harel, I. Schalk, L. Ehret-Sabatier, F. Bouet, M. Goeldner, C. Hirth, P.H. Axelsen, I. Silman, and J.L. Sussman Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase Proc. Natl. Acad. Sci. U.S.A. 90 1993 9031 9035
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 9031-9035
-
-
Harel, M.1
Schalk, I.2
Ehret-Sabatier, L.3
Bouet, F.4
Goeldner, M.5
Hirth, C.6
Axelsen, P.H.7
Silman, I.8
Sussman, J.L.9
-
10
-
-
0033103478
-
Structure of acetylcholinesterase complexed with E2020 (Aricept): Implications for the design of new anti-Alzheimer drugs
-
G. Kryger, I. Sillman, and J.L. Sussman Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs Structure 7 1999 297 307
-
(1999)
Structure
, vol.7
, pp. 297-307
-
-
Kryger, G.1
Sillman, I.2
Sussman, J.L.3
-
11
-
-
84958258163
-
Enzymic hydrolysis and synthesis of acetylcholine
-
D. Nachmansohn, and I.B. Wilson Enzymic hydrolysis and synthesis of acetylcholine Adv. Enzymol. 12 1951 259 339
-
(1951)
Adv. Enzymol.
, vol.12
, pp. 259-339
-
-
Nachmansohn, D.1
Wilson, I.B.2
-
12
-
-
0033524414
-
Substrate binding to the peripheral site of acetylcholinesterase initiates enzymatic catalysis. Substrate inhibition arises as a secondary effect
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T. Szegletes, W.D. Mallender, P.J. Thomas, and T.L. Rosenberry Substrate binding to the peripheral site of acetylcholinesterase initiates enzymatic catalysis. Substrate inhibition arises as a secondary effect Biochemistry 38 1999 122 133
-
(1999)
Biochemistry
, vol.38
, pp. 122-133
-
-
Szegletes, T.1
Mallender, W.D.2
Thomas, P.J.3
Rosenberry, T.L.4
-
13
-
-
0032402388
-
Rapid binding of a cationic active site inhibitor to wild type and mutant mouse acetylcholinesterase: Brownian dynamics simulation including diffusion in the active site gorge
-
S. Tara, A.H. Elcock, P.D. Kirchhoff, J.M. Briggs, Z. Radic, P. Taylor, and J.A. McCammon Rapid binding of a cationic active site inhibitor to wild type and mutant mouse acetylcholinesterase: Brownian dynamics simulation including diffusion in the active site gorge Biopolymers 46 1998 465 474
-
(1998)
Biopolymers
, vol.46
, pp. 465-474
-
-
Tara, S.1
Elcock, A.H.2
Kirchhoff, P.D.3
Briggs, J.M.4
Radic, Z.5
Taylor, P.6
McCammon, J.A.7
-
14
-
-
0034604236
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Acetylthiocholine binds to Asp74 at the peripheral site of human acetylcholinesterase as the first step in the catalytic pathway
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W.D. Mallender, T. Szegletes, and T.L. Rosenberry Acetylthiocholine binds to Asp74 at the peripheral site of human acetylcholinesterase as the first step in the catalytic pathway Biochemistry 39 2000 7753 7763
-
(2000)
Biochemistry
, vol.39
, pp. 7753-7763
-
-
Mallender, W.D.1
Szegletes, T.2
Rosenberry, T.L.3
-
15
-
-
0000140355
-
Nonequilibrium analysis alters the mechanistic interpretation of inhibition of acetylcholinesterase by peripheral site ligands
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T. Szegletes, W.D. Mallender, and T.L. Rosenberry Nonequilibrium analysis alters the mechanistic interpretation of inhibition of acetylcholinesterase by peripheral site ligands Biochemistry 37 1998 4206 4216
-
(1998)
Biochemistry
, vol.37
, pp. 4206-4216
-
-
Szegletes, T.1
Mallender, W.D.2
Rosenberry, T.L.3
-
16
-
-
0038219567
-
Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate
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J.L. Johnson, B. Cusack, M.P. Davies, A. Fauq, and T.L. Rosenberry Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate Biochemistry 42 2003 5438 5452
-
(2003)
Biochemistry
, vol.42
, pp. 5438-5452
-
-
Johnson, J.L.1
Cusack, B.2
Davies, M.P.3
Fauq, A.4
Rosenberry, T.L.5
-
17
-
-
0030583585
-
Structural modifications of the ω loop in human acetylcholinesterase
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B. Velan, D. Barak, N. Ariel, M. Leitner, T. Bino, A. Ordentlich, and A. Shafferman Structural modifications of the ω loop in human acetylcholinesterase FEBS Lett. 395 1996 22 28
-
(1996)
FEBS Lett.
, vol.395
, pp. 22-28
-
-
Velan, B.1
Barak, D.2
Ariel, N.3
Leitner, M.4
Bino, T.5
Ordentlich, A.6
Shafferman, A.7
-
18
-
-
0026540411
-
The alpha/beta hydrolase fold
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D.L. Ollis, E. Cheah, M. Cygler, B. Dijkstra, F. Frolow, S.M. Franken, M. Harel, S.J. Remington, I. Silman, J. Schrag, J.L. Sussman, K.H.G. Verschueren, and A. Goldman The alpha/beta hydrolase fold Protein Eng. 5 1992 197 211
-
(1992)
Protein Eng.
, vol.5
, pp. 197-211
-
-
Ollis, D.L.1
Cheah, E.2
Cygler, M.3
Dijkstra, B.4
Frolow, F.5
Franken, S.M.6
Harel, M.7
Remington, S.J.8
Silman, I.9
Schrag, J.10
Sussman, J.L.11
Verschueren, K.H.G.12
Goldman, A.13
-
19
-
-
0018777146
-
Quantitative simulation of endplate currents at neuro-muscular junctions based on the reactions of acetylcholine with acetylcholine receptor and acetylcholinesterase
-
T.L. Rosenberry Quantitative simulation of endplate currents at neuro-muscular junctions based on the reactions of acetylcholine with acetylcholine receptor and acetylcholinesterase Biophys. J. 26 1979 263 290
-
(1979)
Biophys. J.
, vol.26
, pp. 263-290
-
-
Rosenberry, T.L.1
-
20
-
-
0033605661
-
Organophosphorylation of acetylcholinesterase in the presence of peripheral site ligands: Distinct effects of propidium and fasciculin
-
W.D. Mallender, T. Szegletes, and T.L. Rosenberry Organophosphorylation of acetylcholinesterase in the presence of peripheral site ligands: distinct effects of propidium and fasciculin J. Biol. Chem. 274 1999 8491 8499
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8491-8499
-
-
Mallender, W.D.1
Szegletes, T.2
Rosenberry, T.L.3
-
21
-
-
0141866710
-
Tethering of ligands near the active site of acetylcholinesterase mutant H287C: Progress on a new strategy for protection against organophosphate inactivation
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J.L. Johnson, B.M. Cusack, T.F. Hughes, E.H. McCullough, A. Fauq, P.V. Romanovskis, A.F. Spatola, and T.L. Rosenberry Tethering of ligands near the active site of acetylcholinesterase mutant H287C: progress on a new strategy for protection against organophosphate inactivation J. Biol. Chem. 278 2003 38948 38955
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38948-38955
-
-
Johnson, J.L.1
Cusack, B.M.2
Hughes, T.F.3
McCullough, E.H.4
Fauq, A.5
Romanovskis, P.V.6
Spatola, A.F.7
Rosenberry, T.L.8
-
22
-
-
0016157081
-
A steady-state kinetic model of butyrylcholinesterase from horse plasma
-
K.B. Augustinsson, T. Bartfai, and B. Mannervik A steady-state kinetic model of butyrylcholinesterase from horse plasma Biochem. J. 141 1974 825 834
-
(1974)
Biochem. J.
, vol.141
, pp. 825-834
-
-
Augustinsson, K.B.1
Bartfai, T.2
Mannervik, B.3
-
24
-
-
0023605724
-
Horse serum butyrylcholinesterase kinetics: A molecular mechanism based on inhibition studies with dansylaminoethyltrimethylammonium
-
G. Cauet, A. Friboulet, and D. Thomas Horse serum butyrylcholinesterase kinetics: a molecular mechanism based on inhibition studies with dansylaminoethyltrimethylammonium Biochem. Cell Biol. 65 1987 529 535
-
(1987)
Biochem. Cell Biol.
, vol.65
, pp. 529-535
-
-
Cauet, G.1
Friboulet, A.2
Thomas, D.3
-
26
-
-
0032518976
-
Two invertebrate acetylcholinesterases show activation followed by inhibition with substrate concentration
-
V. Marcel, L. Palacios, C. Pertuy, P. Masson, and D. Fournier Two invertebrate acetylcholinesterases show activation followed by inhibition with substrate concentration Biochem. J. 329 1998 329 334
-
(1998)
Biochem. J.
, vol.329
, pp. 329-334
-
-
Marcel, V.1
Palacios, L.2
Pertuy, C.3
Masson, P.4
Fournier, D.5
-
27
-
-
15844422678
-
The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase
-
M. Harel, D.M. Quinn, H.K. Nair, I. Silman, and J.L. Sussman The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase J. Am. Chem. Soc. 118 1996 2340 2346
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 2340-2346
-
-
Harel, M.1
Quinn, D.M.2
Nair, H.K.3
Silman, I.4
Sussman, J.L.5
-
28
-
-
0035968202
-
Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites
-
G.V. De Ferrari, W.D. Mallender, N.C. Inestrosa, and T.L. Rosenberry Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites J. Biol. Chem. 276 2001 23282 23287
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23282-23287
-
-
De Ferrari, G.V.1
Mallender, W.D.2
Inestrosa, N.C.3
Rosenberry, T.L.4
-
29
-
-
0035947579
-
Involvement of deacylation in activation of substrate hydrolysis by Drosophila acetylcholinesterase
-
L. Brochier, Y. Pontie, M. Willson, S. Estrada-Mondaca, J. Czaplicki, A. Klaebe, and D. Fournier Involvement of deacylation in activation of substrate hydrolysis by Drosophila acetylcholinesterase J. Biol. Chem. 276 2001 18296 18302
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18296-18302
-
-
Brochier, L.1
Pontie, Y.2
Willson, M.3
Estrada-Mondaca, S.4
Czaplicki, J.5
Klaebe, A.6
Fournier, D.7
-
30
-
-
1942520265
-
Inhibition of Drosophila melanogaster acetylcholinesterase by high concentrations of substrate
-
J. Stojan, L. Brochier, C. Alies, J.P. Colletier, and D. Fournier Inhibition of Drosophila melanogaster acetylcholinesterase by high concentrations of substrate Eur. J. Biochem. 271 2004 1364 1371
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 1364-1371
-
-
Stojan, J.1
Brochier, L.2
Alies, C.3
Colletier, J.P.4
Fournier, D.5
-
31
-
-
9644273861
-
Rational polynomial equation as an unbiased approach for the kinetic studies of Drosophila melanogaster acetylcholinesterase reaction mechanism
-
J. Stojan, M. Golicnik, and D. Fournier Rational polynomial equation as an unbiased approach for the kinetic studies of Drosophila melanogaster acetylcholinesterase reaction mechanism Biochim. Biophys. Acta 1703 2004 53 61
-
(2004)
Biochim. Biophys. Acta
, vol.1703
, pp. 53-61
-
-
Stojan, J.1
Golicnik, M.2
Fournier, D.3
-
32
-
-
0015241519
-
Studies of catalysis by acetylcholinesterase: Fluorescent titration with a carbamoylating agent
-
T.L. Rosenberry, and S.A. Bernhard Studies of catalysis by acetylcholinesterase: Fluorescent titration with a carbamoylating agent Biochemistry 10 1971 4114 4120
-
(1971)
Biochemistry
, vol.10
, pp. 4114-4120
-
-
Rosenberry, T.L.1
Bernhard, S.A.2
-
33
-
-
0015497449
-
Studies on catalysis by acetylcholinesterase: Synergistic effects of inhibitors during hydrolysis of acetic acid esters
-
T.L. Rosenberry, and S.A. Bernhard Studies on catalysis by acetylcholinesterase: Synergistic effects of inhibitors during hydrolysis of acetic acid esters Biochemistry 11 1972 4308 4321
-
(1972)
Biochemistry
, vol.11
, pp. 4308-4321
-
-
Rosenberry, T.L.1
Bernhard, S.A.2
-
34
-
-
0018839204
-
Modulation of acetylcholinesterase activity by peripheral site ligands
-
G. Tomlinson, B. Mutus, and I. McLennan Modulation of acetylcholinesterase activity by peripheral site ligands Mol. Pharmacol. 18 1980 33 39
-
(1980)
Mol. Pharmacol.
, vol.18
, pp. 33-39
-
-
Tomlinson, G.1
Mutus, B.2
McLennan, I.3
-
35
-
-
0022344688
-
Acetylcholinesterase inhibition by eserine: Rate constants of reaction. Part II
-
M. Brufani, S. Lippa, M. Marta, A. Oradei, and M. Pomponi Acetylcholinesterase inhibition by eserine: rate constants of reaction. Part II Ital. J. Biochem. 34 1985 328 340
-
(1985)
Ital. J. Biochem.
, vol.34
, pp. 328-340
-
-
Brufani, M.1
Lippa, S.2
Marta, M.3
Oradei, A.4
Pomponi, M.5
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