Determination of concentration and binding affinity of antibody fragments by use of surface plasmon resonance

Journal of Bioscience and Bioengineering

Volumn 100, Issue 3, 2005, Pages 311-317

  Kikuchi, Yasufumi ^a   Uno, Shinsuke ^a   Nanami, Masahiko ^a   Yoshimura, Yasushi ^a   Iida, Shin Ichiro ^a   Fukushima, Naoshi ^a   Tsuchiya, Masayuki ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Antibody; Diabody; Pharmacokinetics; scFv; Surface plasmon resonance

Indexed keywords

ANTIGENS; BIOSENSORS; BLOOD; PHARMACOKINETICS; PROTEINS; QUALITY CONTROL; SURFACE PLASMON RESONANCE;

CRUDE MATERIALS; DIABODY;

ANTIBODIES;

ANTIBODY; EPITOPE; PEPTIDE; RECOMBINANT PROTEIN;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BIOSENSOR; BLOOD; CONCENTRATION (PARAMETERS); DISSOCIATION; MOUSE; NONHUMAN; PLASMA CLEARANCE; SAMPLE;

ANIMALS; ANTIBODY AFFINITY; ANTIGEN-ANTIBODY REACTIONS; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, SCID; SURFACE PLASMON RESONANCE;

ANIMALIA;

EID: 28744447987     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.100.311     Document Type: Article

References (17)

1. Huston J.S., Levinson D., Mudgett-Hunter M., Tai M.S., Novotny J., Margolies M.N., Ridge R.J., Bruccoleri R.E., Haber E., Crea R., Oppermann H. Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli Proc. Natl. Acad. Sci. USA 85 1988 5879 5883
2. Bird R.E., Hardman K.D., Jacobson J.W., Johnson S., Kaufman B.M., Lee S.M., Lee T., Pope S.H., Riordan G.S., Whitlow M. Single-chain antigen-binding proteins Science 242 1988 423 426
3. Pavlinkova G., Beresford G.W., Booth B.J., Batra S.K., Colcher D. Pharmacokinetics and biodistribution of engineered single-chain antibody constructs of MAb CC49 in colon carcinoma xenografts J. Nucl. Med. 40 1999 1536 1546
4. Milenic D.E., Yokota T., Filpula D.R., Finkelman M.A., Dodd S.W., Wood J.F., Whitlow M., Snoy P., Schlom J. Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49 Cancer Res. 51 1991 6363 6371
5. Adams G.P., McCartney J.E., Tai M.S., Oppermann H., Huston J.S., Stafford W.F. 3rd, Bookman M.A., Fand I., Houston L.L., Weiner L.M. Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv Cancer Res. 53 1993 4026 4033
6. Adams G.P., Schier R., McCall A.M., Crawford R.S., Wolf E.J., Weiner L.M., Marks J.D. Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu Br. J. Cancer 77 1998 1405 1412
7. Beresford G.W., Pavlinkova G., Booth B.J., Batra S.K., Colcher D. Binding characteristics and tumor targeting of a covalently linked divalent CC49 single-chain antibody Int. J. Cancer 81 1999 911 917
8. Kikuchi Y., Uno S., Yoshimura Y., Otabe K., Iida S., Oheda M., Fukushima N., Tsuchiya M. A bivalent single-chain Fv fragment against CD47 induces apoptosis for leukemic cells Biochem. Biophys. Res. Commun. 315 2004 912 918
9. Kikuchi Y., Uno S., Kinoshita Y., Yoshimura Y., Iida S., Wakahara Y., Tsuchiya M., Yamada-Okabe H., Fukushima N. Apoptosis inducing bivalent single-chain antibody fragments against CD47 showed antitumor potency for multiple myeloma Leuk. Res. 29 2005 445 450
10. Hudson P.J., Kortt A.A. High avidity scFv multimers; diabodies and triabodies J. Immunol. Methods 231 1999 177 189
11. Tejedor F., Ballesta J.P. Protein S4 is near the elongation factor G binding site in the ribosome FEBS Lett. 182 1985 253 256
12. George A.J., Danga R., Gooden C.S., Epenetos A.A., Spooner R.A. Quantitative and qualitative detection of serum antibodies using a resonant mirror biosensor Tumor Targeting 1 1995 245 250
13. Wong R.L., Mytych D., Jacobs S., Bordens R., Swanson S.J. Validation parameters for a novel biosensor assay which simultaneously measures serum concentrations of a humanized monoclonal antibody and detects induced antibodies J. Immunol. Methods 209 1997 1 15
14. Ritter G., Cohen L.S., Williams C. Jr., Richards E.C., Old L.J., Welt S. Serological analysis of human anti-human antibody responses in colon cancer patients treated with repeated doses of humanized monoclonal antibody A33 Cancer Res. 61 2001 6851 6859
15. Welt S., Ritter G., Williams C. Jr., Cohen L.S., John M., Jungbluth A., Richards E.A., Old L.J., Kemeny N.E. Phase I study of anticolon cancer humanized antibody A33 Clin. Cancer Res. 9 2003 1338 1346
16. Scott A.M., Geleick D., Rubira M., Clarke K., Nice E.C., Smyth F.E., Stockert E., Richards E.C., Carr F.J., Harris W.J., other 13 authors Construction, production, and characterization of humanized anti-Lewis Y monoclonal antibody 3S193 for targeted immunotherapy of solid tumors Cancer Res. 60 2000 3254 3261
17. Pace C.N., Vajdos F., Fee L., Grimsley G., Gray T. How to measure and predict the molar absorption coefficient of a protein Protein Sci. 4 1995 2411 2423