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Volumn 11, Issue 6, 2004, Pages 345-352

Primary hyperparathyroidism: Diagnosis, evaluation, and treatment

Author keywords

Hypercalcemia; Parathyroid hormone; Parathyroidectomy; Primary hyperparathyroidism

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; CALCIUM; CINACALCET; PARATHYROID HORMONE; R 568; UNCLASSIFIED DRUG;

EID: 28744447058     PISSN: 10683097     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.med.0000144035.12532.a7     Document Type: Review
Times cited : (9)

References (91)
  • 1
    • 0031901781 scopus 로고    scopus 로고
    • A non (1-84) circulating parathyroid hormone (PTH) fragment interferes significantly with intact PTH commercial assay measurements in uremic samples
    • Lepage R, Roy L, Brossard JH, et al.: A non (1-84) circulating parathyroid hormone (PTH) fragment interferes significantly with intact PTH commercial assay measurements in uremic samples. Clin Chem 2004, 44:805-809.
    • (2004) Clin Chem , vol.44 , pp. 805-809
    • Lepage, R.1    Roy, L.2    Brossard, J.H.3
  • 2
    • 0035076316 scopus 로고    scopus 로고
    • Development of a novel immunoradiometric assay exclusively for biologically active whole parathyroid hormone 1-84. Implications for improvement of accurate assessment of parathyroid function
    • Gao P, Scheibel S, D'Amour P, et al.: Development of a novel immunoradiometric assay exclusively for biologically active whole parathyroid hormone 1-84. Implications for improvement of accurate assessment of parathyroid function. J Bone Miner Res. 2001, 16:4:605-614.
    • (2001) J Bone Miner Res , vol.16 , Issue.4 , pp. 605-614
    • Gao, P.1    Scheibel, S.2    D'Amour, P.3
  • 3
    • 0033324250 scopus 로고    scopus 로고
    • A novel immunoradiometric assay detects full-length human PTH but not amino-terminally truncated fragments: Implications for PTH measurement in renal failure
    • John MR, Goodman WG, Gao P, et al.: A novel immunoradiometric assay detects full-length human PTH but not amino-terminally truncated fragments: implications for PTH measurement in renal failure. J Clin Endocrinol Metab 1999, 84:4287-4290.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4287-4290
    • John, M.R.1    Goodman, W.G.2    Gao, P.3
  • 4
    • 0242351809 scopus 로고    scopus 로고
    • Clinical utility of an immunoradiometric assay for whole PTH (1-84) in primary hyperparathyroidism
    • Silverberg SJ, Brown I, LoGerfo P, et al.: Clinical utility of an immunoradiometric assay for whole PTH (1-84) in primary hyperparathyroidism. J Clin Endocrinol Metab 2003, 88:4725-4730. This report compares the newest of the immunoassays for PTH in which only the full-length molecule is detected with several older assays among a cohort of patients with primary hyperparathyroidism.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4725-4730
    • Silverberg, S.J.1    Brown, I.2    LoGerfo, P.3
  • 5
    • 0037244847 scopus 로고    scopus 로고
    • A syndrome of hypocalciuric hypercalcemia caused by autoantibodies directed at the calcium-sensing receptor
    • Kifor O, Moore FD Jr, Delaney M, et al.: a syndrome of hypocalciuric hypercalcemia caused by autoantibodies directed at the calcium-sensing receptor. J Clin Endocrinol Metab 2003, 88:60-72. In this report, endogenously appearing, inactivating antibodies against the calcium receptor give rise to a syndrome very much like familial hypocalciuric hypercalcemia. Characteristics of these patients as well as the anti-calcium receptor antibody are presented.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 60-72
    • Kifor, O.1    Moore Jr., F.D.2    Delaney, M.3
  • 6
    • 3242657067 scopus 로고    scopus 로고
    • Acquired hypocalciuric hypercalcemia due to autoantibodies against the calcium-sensing receptor
    • Pallais JC, Kifor O, Chen Y-B, et al.: Acquired hypocalciuric hypercalcemia due to autoantibodies against the calcium-sensing receptor. N Engl J Med 2004, 351:362-369. Similar to [5], this report provides convincing evidence that antibodies directed against the calcium receptor can lead to a syndrome of acquired hypocalciuric hypercalcemia.
    • (2004) N Engl J Med , vol.351 , pp. 362-369
    • Pallais, J.C.1    Kifor, O.2    Chen, Y.-B.3
  • 7
    • 0242351848 scopus 로고    scopus 로고
    • Normocalcemic primary hyperparathyroidism: Evidence for a generalized target-tissue resistance to parathyroid hormone
    • Maruani G, Hertig A, Paillard M, et al.: Normocalcemic primary hyperparathyroidism: evidence for a generalized target-tissue resistance to parathyroid hormone. J Clin Endocrinol Metab 2003, 88:4641-4648. Patients with primary hyperparathyroidism in whom the serum calcium level is consistently normal are beginning to be described. This paper is one of the first to characterize a group of these patients.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4641-4648
    • Maruani, G.1    Hertig, A.2    Paillard, M.3
  • 8
    • 0345305420 scopus 로고    scopus 로고
    • Incipient" primary hyperparathyroidism: A "forme fruste" of an old disease
    • Silverberg SJ, Bilezikian JP: "Incipient" primary hyperparathyroidism: a "forme fruste" of an old disease. J Clin Endocrinol Metab 2003, 88:5348-5352. Similar to [7], this report is one of the first to describe a syndrome in which patients with primary hyperparathyroidism have normal serum calcium levels. The entity, normocalcemic primary hyperparathyroidism, is now being seen more and more commonly. Reasons for this and concepts related to the evolution of the primary hyperparathyroid state are described in this article.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5348-5352
    • Silverberg, S.J.1    Bilezikian, J.P.2
  • 9
    • 0024232204 scopus 로고
    • Lack of biochemical progression or continuation of accelerated bone loss in mild asymptomatic primary hyperparathyroidism
    • Rao DS, Wilson RJ, Kleerekoper M, et al.: Lack of biochemical progression or continuation of accelerated bone loss in mild asymptomatic primary hyperparathyroidism. J Clin Endocrinol Metab 1988, 67:1294-1298.
    • (1988) J Clin Endocrinol Metab , vol.67 , pp. 1294-1298
    • Rao, D.S.1    Wilson, R.J.2    Kleerekoper, M.3
  • 10
    • 0028913683 scopus 로고
    • Longitudinal measurements of bone density and biochemical indices in untreated primary hyperparathyroidism
    • Silverberg SJ, Gartenberg F, Jacobs TP, et al.: Longitudinal measurements of bone density and biochemical indices in untreated primary hyperparathyroidism. J Clin Endocrinol Metab 1995, 80:723-238.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 723-1238
    • Silverberg, S.J.1    Gartenberg, F.2    Jacobs, T.P.3
  • 11
    • 0002238992 scopus 로고
    • Characterization and evaluation of asymptomatic primary hyperparathyroidism
    • Bilezikian JP, Silverberg SJ, Shane E, et al.: Characterization and evaluation of asymptomatic primary hyperparathyroidism. J Bone Miner Res 1991, 6(suppl I):585-589.
    • (1991) J Bone Miner Res , vol.6 , Issue.SUPPL. I , pp. 585-589
    • Bilezikian, J.P.1    Silverberg, S.J.2    Shane, E.3
  • 12
    • 0024346202 scopus 로고
    • Skeletal disease in primary hyperparathyroidism
    • Silverberg SJ, Shane E, Delacruz L, et al.: Skeletal disease in primary hyperparathyroidism. J Bone Miner Res 1989, 4:283-291.
    • (1989) J Bone Miner Res , vol.4 , pp. 283-291
    • Silverberg, S.J.1    Shane, E.2    Delacruz, L.3
  • 13
    • 0029846634 scopus 로고    scopus 로고
    • Vertebral osteopenia: A new indication for surgery in primary hyperparathyroidism
    • Silverberg SJ, Locker FG, Bilezikian JP: Vertebral osteopenia: a new indication for surgery in primary hyperparathyroidism. J Clin Endocrinol Metab 1996, 81:4007-4012.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4007-4012
    • Silverberg, S.J.1    Locker, F.G.2    Bilezikian, J.P.3
  • 14
    • 0025343027 scopus 로고
    • The histomorphometry of bone in primary hyperparathyroidism: Preservation of cancellous bone structure
    • Parisien M, Silverberg SJ, Shane E, et al.: The histomorphometry of bone in primary hyperparathyroidism: preservation of cancellous bone structure. J Clin Endocrinol Metab 1990, 70:930-938.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 930-938
    • Parisien, M.1    Silverberg, S.J.2    Shane, E.3
  • 15
    • 0002152841 scopus 로고
    • Surface specific bone remodeling in health and disease
    • edited by Kleerekoper M. New York: Mary Ann Liebert
    • Parfitt AM: Surface specific bone remodeling in health and disease. In Clinical Disorders of Bone and Mineral Metabolism, edited by Kleerekoper M. New York: Mary Ann Liebert, 1989:7-14.
    • (1989) Clinical Disorders of Bone and Mineral Metabolism , pp. 7-14
    • Parfitt, A.M.1
  • 16
    • 0029145150 scopus 로고
    • Bone structure in postmenopausal hyperparathyroid, osteoporotic and normal women
    • Parisien M, Cosman F, Mellish RWE, et al.: Bone structure in postmenopausal hyperparathyroid, osteoporotic and normal women. J Bone Miner Res 1995, 10:1393-1399.
    • (1995) J Bone Miner Res , vol.10 , pp. 1393-1399
    • Parisien, M.1    Cosman, F.2    Mellish, R.W.E.3
  • 17
    • 0026667476 scopus 로고
    • Maintenance of cancellous bone connectivity in primary hyperparathyroidism: Trabecular and strut analysis
    • Parisien M, Mellish RWE, Silverberg SJ, et al.: Maintenance of cancellous bone connectivity in primary hyperparathyroidism: trabecular and strut analysis. J Bone Miner Res 1992, 7:913-920.
    • (1992) J Bone Miner Res , vol.7 , pp. 913-920
    • Parisien, M.1    Mellish, R.W.E.2    Silverberg, S.J.3
  • 18
    • 0033345813 scopus 로고    scopus 로고
    • On the mechanism of cancellous bone preservation in postmenopausal women with mild primary hyperparathyroidism
    • Dempster DW, Parisien M, Silverberg SJ, et al.: On the mechanism of cancellous bone preservation in postmenopausal women with mild primary hyperparathyroidism. J Clin Endocrinol Metab 1999, 84:1562-1566.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1562-1566
    • Dempster, D.W.1    Parisien, M.2    Silverberg, S.J.3
  • 19
    • 0016771424 scopus 로고
    • Back pain and vertebral crush fractures: An unemphasized mode of presentation for primary hyperparathyroidism
    • Dauphine RT, Riggs BL, Scholz DA: Back pain and vertebral crush fractures: an unemphasized mode of presentation for primary hyperparathyroidism. Ann Intern Med 1975, 83:365-367.
    • (1975) Ann Intern Med , vol.83 , pp. 365-367
    • Dauphine, R.T.1    Riggs, B.L.2    Scholz, D.A.3
  • 20
    • 0023469723 scopus 로고
    • What is the clinical significance of bone loss in primary hyperparathyroidism
    • Kochesberger G, Buckley NJ, Leight GS, et al.: What is the clinical significance of bone loss in primary hyperparathyroidism. Arch Intern Med 1987, 147:1951-1953.
    • (1987) Arch Intern Med , vol.147 , pp. 1951-1953
    • Kochesberger, G.1    Buckley, N.J.2    Leight, G.S.3
  • 21
    • 0024263299 scopus 로고
    • Mild asymptomatic primary hyperparathyroidism is not a risk factor for vertebral fractures
    • Wilson RJ, Rao S, Ellis B, et al.: Mild asymptomatic primary hyperparathyroidism is not a risk factor for vertebral fractures. Ann Intern Med 1988, 109:959-962.
    • (1988) Ann Intern Med , vol.109 , pp. 959-962
    • Wilson, R.J.1    Rao, S.2    Ellis, B.3
  • 22
    • 0027144911 scopus 로고
    • The risk of hip fractures in patients with primary hyperparathyroidism: A population-based cohort study with a follow-up of 19 years
    • Larsson K, Ljunghall S, Krusemo UB, et al.: The risk of hip fractures in patients with primary hyperparathyroidism: a population-based cohort study with a follow-up of 19 years. J Intern Med 1993, 234:585-593.
    • (1993) J Intern Med , vol.234 , pp. 585-593
    • Larsson, K.1    Ljunghall, S.2    Krusemo, U.B.3
  • 23
    • 0029073753 scopus 로고
    • Fracture incidence in post-menopausal women with primary hyperparathyroidism
    • Kenny AM, MacGillivray DC, Pilbeam CC, et al.: Fracture incidence in post-menopausal women with primary hyperparathyroidism. Surgery 1995, 118:109-114.
    • (1995) Surgery , vol.118 , pp. 109-114
    • Kenny, A.M.1    MacGillivray, D.C.2    Pilbeam, C.C.3
  • 24
    • 0032835427 scopus 로고    scopus 로고
    • Primary hyperparathyroidism and the risk of fracture: A population-based study
    • Khosla S, Melton LJ, Wermers RA, et al.: Primary hyperparathyroidism and the risk of fracture: a population-based study. J Bone Miner Res 1999, 14:1700-1707.
    • (1999) J Bone Miner Res , vol.14 , pp. 1700-1707
    • Khosla, S.1    Melton, L.J.2    Wermers, R.A.3
  • 25
    • 0031959112 scopus 로고    scopus 로고
    • Bone measurements in asymptomatic primary hyperparathyroidism
    • Adami S, Braga V, Squaranti R, et al.: Bone measurements in asymptomatic primary hyperparathyroidism. Bone 1998, 22:565-570.
    • (1998) Bone , vol.22 , pp. 565-570
    • Adami, S.1    Braga, V.2    Squaranti, R.3
  • 26
    • 0242320435 scopus 로고    scopus 로고
    • Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects
    • Chen Q, Kaji H, Iu M-F, et al.: Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects. J Clin Endocrinol Metab 2003, 88:4655-4658. Besides affecting bone mineral density, it is now known that PTH has important effects on bone size. Using peripheral quantitative CT, Chen et al. provide data confirming the idea, presented first by Adami et al. [25], that PTH affects cross-sectional areas of bone and bone density.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4655-4658
    • Chen, Q.1    Kaji, H.2    Iu, M.-F.3
  • 27
    • 0036786340 scopus 로고    scopus 로고
    • Parathyroid hormone and periosteal bone expansion
    • Parfitt AM: Parathyroid hormone and periosteal bone expansion. J Bone Miner Res 2002, 17:1741-1743.
    • (2002) J Bone Miner Res , vol.17 , pp. 1741-1743
    • Parfitt, A.M.1
  • 28
    • 3242669697 scopus 로고    scopus 로고
    • Bone strength in primary hyperparathyroidism
    • Bilezikian JP: Bone strength in primary hyperparathyroidism. Osteoporos Int 2003, 14(suppl 5):5113-5117. Because PTH affects a number of different parameters that help to define bone strength, it is not clear whether bone density alone can accurately predict fracture risk in primary hyperparathyroidism. In this paper, Bilezikian considers these other factors.
    • (2003) Osteoporos Int , vol.14 , Issue.SUPPL. 5 , pp. 5113-5117
    • Bilezikian, J.P.1
  • 29
    • 12344317430 scopus 로고    scopus 로고
    • Nephrolithiasis in primary hyperparathyroidism
    • edited by Bilezikian JP. New York: Academic Press
    • Klugman VA, Favus M, Pak CYC: Nephrolithiasis in primary hyperparathyroidism. In The Parathyroids: Basic and Clinical Concepts, edited by Bilezikian JP. New York: Academic Press, 2001:437-450.
    • (2001) The Parathyroids: Basic and Clinical Concepts , pp. 437-450
    • Klugman, V.A.1    Favus, M.2    Pak, C.Y.C.3
  • 30
    • 0036841350 scopus 로고    scopus 로고
    • Non-classical target organs in primary hyperparathyroidism
    • Silverberg SJ: Non-classical target organs in primary hyperparathyroidism. J Bone Miner Res 2003, 17(suppl 2):N117-N125. In asymptomatic primary hyperparathyroidism, by far the most common presentation of the disease in the developed world, guidelines call for evaluation of the skeleton and the kidney, the two most common target organs in this disorder. In this paper, Silverberg covers other potential target organs in primary hyperparathyroidism and their potential for involvement even in asymptomatic disease.
    • (2003) J Bone Miner Res , vol.17 , Issue.SUPPL. 2
    • Silverberg, S.J.1
  • 32
    • 0024325138 scopus 로고
    • Neuromuscular involvement in mild, asymptomatic primary hyperparathyroidism
    • Turken SA, Cafferty M, Silverberg SJ, et al.: Neuromuscular involvement in mild, asymptomatic primary hyperparathyroidism. Am J Med 1989, 87:553-557.
    • (1989) Am J Med , vol.87 , pp. 553-557
    • Turken, S.A.1    Cafferty, M.2    Silverberg, S.J.3
  • 33
    • 0023753231 scopus 로고    scopus 로고
    • Psychiatric morbidity in primary hyperparathyroidism
    • Joborn C, Hetta J, Johansson H, et al.: Psychiatric morbidity in primary hyperparathyroidism. World J Surg 1998, 2:476-481.
    • (1998) World J Surg , vol.2 , pp. 476-481
    • Joborn, C.1    Hetta, J.2    Johansson, H.3
  • 34
    • 0028261499 scopus 로고
    • Psychologic symptoms before and after parathyroid surgery
    • Solomon BL, Schaaf M, Smallridge RC: Psychologic symptoms before and after parathyroid surgery. Am J Med 1994, 96:101-106.
    • (1994) Am J Med , vol.96 , pp. 101-106
    • Solomon, B.L.1    Schaaf, M.2    Smallridge, R.C.3
  • 35
    • 0032990443 scopus 로고    scopus 로고
    • Health status improvement after surgical correction of primary hyperparathyroidism in patients with high and low preoperative calcium levels
    • Burney RE, Jones KR, Christy B, et al.: Health status improvement after surgical correction of primary hyperparathyroidism in patients with high and low preoperative calcium levels. Surgery 1999, 125:608-614.
    • (1999) Surgery , vol.125 , pp. 608-614
    • Burney, R.E.1    Jones, K.R.2    Christy, B.3
  • 36
    • 0033666126 scopus 로고    scopus 로고
    • Randomized trial of parathyroidectomy in mild asymptomatic primary hyperparathyroidism: Patient description and effects on the SF-36 health survey
    • Talpos GB, Bone HG, Kleerekoper M, et al.: Randomized trial of parathyroidectomy in mild asymptomatic primary hyperparathyroidism: patient description and effects on the SF-36 health survey. Surgery 2000, 128:1013-1020.
    • (2000) Surgery , vol.128 , pp. 1013-1020
    • Talpos, G.B.1    Bone, H.G.2    Kleerekoper, M.3
  • 37
    • 0023625282 scopus 로고
    • Neurobehavioral symptoms in mild hyperparathyroidism: Related to hypercalcemia but not improved by parathyroidectomy
    • Brown GG, Preisman RC, Kleerekoper MD: Neurobehavioral symptoms in mild hyperparathyroidism: related to hypercalcemia but not improved by parathyroidectomy. Henry Ford Med J 1987, 35:211-215.
    • (1987) Henry Ford Med J , vol.35 , pp. 211-215
    • Brown, G.G.1    Preisman, R.C.2    Kleerekoper, M.D.3
  • 38
    • 0019819511 scopus 로고
    • Primary hyperparathyroidism: Changing clinical spectrum, prevalence of hypertension, and discriminant analysis of laboratory tests
    • Lafferty FW: Primary hyperparathyroidism: changing clinical spectrum, prevalence of hypertension, and discriminant analysis of laboratory tests. Arch Intern Med 1981, 141:1761-1766.
    • (1981) Arch Intern Med , vol.141 , pp. 1761-1766
    • Lafferty, F.W.1
  • 39
    • 0022412557 scopus 로고
    • Cardiac hypertrophy, hypertrophic cardiomyopathy and hyperparathyroidism- an association
    • Symons C, Fortune F, Greenbaum RA, et al.: Cardiac hypertrophy, hypertrophic cardiomyopathy and hyperparathyroidism-an association. Br Heart J 1985, 54:539-542.
    • (1985) Br Heart J , vol.54 , pp. 539-542
    • Symons, C.1    Fortune, F.2    Greenbaum, R.A.3
  • 40
    • 0027180466 scopus 로고
    • Primary hyperparathyroidism: Incidence of cardiac abnormalities and partial reversibility after successful parathyroidectomy
    • Stefenelli T, Mayr H, Bergler-Klein J, et al.: Primary hyperparathyroidism: incidence of cardiac abnormalities and partial reversibility after successful parathyroidectomy. Am J Med 1993, 95:197-202.
    • (1993) Am J Med , vol.95 , pp. 197-202
    • Stefenelli, T.1    Mayr, H.2    Bergler-Klein, J.3
  • 41
    • 0027180466 scopus 로고
    • Primary hyperparathyroidism: Incidence of cardiac abnormalities and partial reversibility after successful parathyroidectomy
    • Stefenelli T, Mayr H, Berger-Klein J, et al.: Primary hyperparathyroidism: incidence of cardiac abnormalities and partial reversibility after successful parathyroidectomy. Am J Med 1993, 95:197-202.
    • (1993) Am J Med , vol.95 , pp. 197-202
    • Stefenelli, T.1    Mayr, H.2    Berger-Klein, J.3
  • 42
    • 0034457598 scopus 로고    scopus 로고
    • Cardiovascular effects of parathyroid hormone: A study in healthy subjects and normotensive patients with mild hyperparathyroidism
    • Barletta G, De Feo ML, Del Bene R, et al.: Cardiovascular effects of parathyroid hormone: a study in healthy subjects and normotensive patients with mild hyperparathyroidism. J Clin Endocrinol Metab 2000, 85:1815-1821.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1815-1821
    • Barletta, G.1    De Feo, M.L.2    Del Bene, R.3
  • 43
    • 0033767473 scopus 로고    scopus 로고
    • Augmentation of central arterial pressure in mild primary hyperparathyroidism
    • Smith JC, Page MD, Wheeler MH, et al.: Augmentation of central arterial pressure in mild primary hyperparathyroidism. J Clin Endocrinol Metab 2000, 85:3515-3519.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3515-3519
    • Smith, J.C.1    Page, M.D.2    Wheeler, M.H.3
  • 44
    • 12344255373 scopus 로고    scopus 로고
    • Vascular stiffness is increased in patients with primary hyperparathyroidism
    • Rubin MR, Bilezikian JP, Silverberg SJ: Vascular stiffness is increased in patients with primary hyperparathyroidism. J Bone Miner Res 2002, 17:S381.
    • (2002) J Bone Miner Res , vol.17
    • Rubin, M.R.1    Bilezikian, J.P.2    Silverberg, S.J.3
  • 45
    • 0029123005 scopus 로고
    • Vitamin D status in primary hyperparathyroidism in India
    • Harinarayan DV, Gupta N, Kochupillai N: Vitamin D status in primary hyperparathyroidism in India. Clin Endocrinol 1995, 43:351-358.
    • (1995) Clin Endocrinol , vol.43 , pp. 351-358
    • Harinarayan, D.V.1    Gupta, N.2    Kochupillai, N.3
  • 46
    • 0028373870 scopus 로고
    • The diagnosis of primary hyperparathyroidism-analysis of 134 cases
    • Meng XW, Xing XP, Liu SQ, et al.: The diagnosis of primary hyperparathyroidism-analysis of 134 cases. Acta Acad Med Sin 1994, 16:116-122.
    • (1994) Acta Acad Med Sin , vol.16 , pp. 116-122
    • Meng, X.W.1    Xing, X.P.2    Liu, S.Q.3
  • 47
    • 0042883294 scopus 로고    scopus 로고
    • Coexisting hyperthyroidism and hyperparathyroidism with vitamin D deficient osteomalacia in a Vietnamese immigrant
    • Luong KVQ, Nguyen LTH: Coexisting hyperthyroidism and hyperparathyroidism with vitamin D deficient osteomalacia in a Vietnamese immigrant. Endocr Pract 1996, 2:250-254.
    • (1996) Endocr Pract , vol.2 , pp. 250-254
    • Luong, K.V.Q.1    Nguyen, L.T.H.2
  • 48
    • 0016230851 scopus 로고
    • Parathyroid function in vitamin D deficiency in primary hyperparathyroidism
    • Lumb GA, Stanbury SW: Parathyroid function in vitamin D deficiency in primary hyperparathyroidism. Am J Med 1974, 54:833-839.
    • (1974) Am J Med , vol.54 , pp. 833-839
    • Lumb, G.A.1    Stanbury, S.W.2
  • 49
    • 0032764057 scopus 로고    scopus 로고
    • Vitamin D deficiency in primary hyperparathyroidism
    • Silverberg SJ, Shane E, Dempster DW, et al.: Vitamin D deficiency in primary hyperparathyroidism. Am J Med 1999, 107:561-567.
    • (1999) Am J Med , vol.107 , pp. 561-567
    • Silverberg, S.J.1    Shane, E.2    Dempster, D.W.3
  • 50
    • 0023214038 scopus 로고
    • Mortality after surgery for primary hyperparathyroidism. A follow-up of 441 patients operated on from 1956 to 1979
    • Palmer M, Adami HO, Bergstrom R, et al.: Mortality after surgery for primary hyperparathyroidism. A follow-up of 441 patients operated on from 1956 to 1979. Surgery 1987, 102:1-7.
    • (1987) Surgery , vol.102 , pp. 1-7
    • Palmer, M.1    Adami, H.O.2    Bergstrom, R.3
  • 51
    • 0023130098 scopus 로고
    • Survival and renal function in untreated hypercalcemia
    • Palmer M, Adami HO, Bergstrom G, et al.: Survival and renal function in untreated hypercalcemia. Lancet 1987, 1:59-62.
    • (1987) Lancet , vol.1 , pp. 59-62
    • Palmer, M.1    Adami, H.O.2    Bergstrom, G.3
  • 52
    • 0345742604 scopus 로고    scopus 로고
    • Increased mortality in patients hospitalized with primary hyperparathyroidism during the period 1977-1993 in Denmark
    • Ogard CG, Engholm G, Almdal TP, et al.: Increased mortality in patients hospitalized with primary hyperparathyroidism during the period 1977-1993 in Denmark. World J Surg 2004,:108-111. Accurate mortality figures are hard to confirm in this disorder because epidemiologic databases are uncommon. In this paper, Ogard et al. present data from a well-characterized database from Denmark, suggesting that mortality is increased in this disorder. Whether these observations are applicable to other cohorts of patients with primary hyperparathyroidism in whom signs and symptoms may differ is not clear.
    • (2004) World J Surg , pp. 108-111
    • Ogard, C.G.1    Engholm, G.2    Almdal, T.P.3
  • 53
    • 0032005049 scopus 로고    scopus 로고
    • Survival after the diagnosis of hyperparathyroidism
    • Wermers RA, Khosla S, Atkinson EJ, et al.: Survival after the diagnosis of hyperparathyroidism. Am J Med 1998, 104:115-122.
    • (1998) Am J Med , vol.104 , pp. 115-122
    • Wermers, R.A.1    Khosla, S.2    Atkinson, E.J.3
  • 54
    • 0025790207 scopus 로고
    • Consensus development conference statement on primary hyperparathyroidism
    • National Institutes of Health: Consensus development conference statement on primary hyperparathyroidism. J Bone Miner Res 1991, 6:s9-s13.
    • (1991) J Bone Miner Res , vol.6
  • 56
    • 0036925217 scopus 로고    scopus 로고
    • also published in
    • (also published in J Clin Endocrinol Metab 2002, 87:5353-5361).
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5353-5361
  • 57
    • 2142663023 scopus 로고    scopus 로고
    • Standards and guidelines for diagnosis and management in Canada
    • Consensus Development Task Force on Diagnosis and Management of Asymptomatic Primary Hyperparathyroidism
    • Consensus Development Task Force on Diagnosis and Management of Asymptomatic Primary Hyperparathyroidism: Standards and guidelines for diagnosis and management in Canada. Endocr Pract 2003, 9:400-405. After the publication emanating from the Workshop on Asymptomatic Primary Hyperparathyroidism [55], this paper follows with a consideration of how these guidelines are applicable to Canadians and their health system.
    • (2003) Endocr Pract , vol.9 , pp. 400-405
  • 58
    • 0042265154 scopus 로고    scopus 로고
    • How should patients with primary hyperparathyroidism be treated?
    • Clark OH: How should patients with primary hyperparathyroidism be treated? J Clin Endocrinol Metab 2003, 88:3011-3014. This is an insightful editorial written by a prominent parathyroid surgeon.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3011-3014
    • Clark, O.H.1
  • 59
    • 1542344989 scopus 로고    scopus 로고
    • Prospective evaluation of ultrasonography plus MIBI scintigraphy in selecting patients with primary hyperparathyroidism for unilateral neck exploration under local anesthesia
    • Saint MO, Cogliandolo A, Pidoto RR, et al.: Prospective evaluation of ultrasonography plus MIBI scintigraphy in selecting patients with primary hyperparathyroidism for unilateral neck exploration under local anesthesia. Am J Surg 2004, 187:388-393. With advances in imaging, this paper describes how preoperative localization can help to decide which kind of parathyroid surgery to perform.
    • (2004) Am J Surg , vol.187 , pp. 388-393
    • Saint, M.O.1    Cogliandolo, A.2    Pidoto, R.R.3
  • 60
    • 0033844108 scopus 로고    scopus 로고
    • One hundred consecutive minimally invasive parathyroid explorations
    • Udelsman R, Donovan POI, Sokoll LT: One hundred consecutive minimally invasive parathyroid explorations. Ann Surg 2000, 232:331-339.
    • (2000) Ann Surg , vol.232 , pp. 331-339
    • Udelsman, R.1    Donovan, P.O.I.2    Sokoll, L.T.3
  • 61
    • 1042269525 scopus 로고    scopus 로고
    • Parathyroid surgical failures with misleading falls of intraoperative parathyroid hormone levels
    • Hoyanyi J, Duffek L, Szlavik R, et al.: Parathyroid surgical failures with misleading falls of intraoperative parathyroid hormone levels. J Endocrinol Invest 2003, 26:1095-1099. Not all patients whose intraoperative PTH levels fall to below 50% of the baseline value after removal of a single adenoma are cured.
    • (2003) J Endocrinol Invest , vol.26 , pp. 1095-1099
    • Hoyanyi, J.1    Duffek, L.2    Szlavik, R.3
  • 62
    • 0344837914 scopus 로고    scopus 로고
    • Differing histologic findings after bilateral and focused parathyroidectomy
    • Gene H, Morita E, Perrier ND, et al.: Differing histologic findings after bilateral and focused parathyroidectomy. J Am Coll Surg 2003, 196:535-540. Differing histologic pictures of single- and multiple-gland disease are presented.
    • (2003) J Am Coll Surg , vol.196 , pp. 535-540
    • Gene, H.1    Morita, E.2    Perrier, N.D.3
  • 63
    • 0038637318 scopus 로고    scopus 로고
    • The impact of sestamibi scanning on the outcome of parathyroid surgery
    • Allendorf J, Kim L, Chabot J, et al.: The impact of sestamibi scanning on the outcome of parathyroid surgery. J Clin Endocrinol Metab 2003, 88:3015-3018. The late, great parathyroid surgeon Paul LoGerfo described a largo amount of experience with and without preoperative sestamibi scanning
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3015-3018
    • Allendorf, J.1    Kim, L.2    Chabot, J.3
  • 64
    • 0346887055 scopus 로고    scopus 로고
    • The impact of minimally invasive parathyroidectomy on the way endocrinologists treat primary hyperparathyroidism
    • Gallagher SF, Denham DW, Murr MM, et al.: The impact of minimally invasive parathyroidectomy on the way endocrinologists treat primary hyperparathyroidism. Surgery 2003, 134:910-917. The availability of minimally invasive parathyroid surgery is influencing the way in which this disease is being managed.
    • (2003) Surgery , vol.134 , pp. 910-917
    • Gallagher, S.F.1    Denham, D.W.2    Murr, M.M.3
  • 65
    • 3242666961 scopus 로고    scopus 로고
    • Minimally invasive parathyroidectomy: How effective is preoperative sestamibi scanning?
    • Vassy WM, Nelson HS Jr, Mancini ML, et al.: Minimally invasive parathyroidectomy: how effective is preoperative sestamibi scanning? Am Surg 2003, 69:1090-1094. A discussion is presented about the utility of preoperative sestamibi scanning for the minimally invasive procedure.
    • (2003) Am Surg , vol.69 , pp. 1090-1094
    • Vassy, W.M.1    Nelson Jr., H.S.2    Mancini, M.L.3
  • 66
    • 0346147051 scopus 로고    scopus 로고
    • New directions in the treatment of patients with primary hyperparathyroidism
    • Sosa JA, Udelsman R: New directions in the treatment of patients with primary hyperparathyroidism. Curr Probl Surg 2003, 40:812-849. Robert Udelsman, one of the pioneers of the minimally invasive parathyroidectomy, provides a perspective of that and other surgical approaches to this disease.
    • (2003) Curr Probl Surg , vol.40 , pp. 812-849
    • Sosa, J.A.1    Udelsman, R.2
  • 67
    • 2342613545 scopus 로고    scopus 로고
    • Management of asymptomatic primary hyperparathyroidism
    • Bilezikian JP, Silverberg SJ: Management of asymptomatic primary hyperparathyroidism. N Engl J Med 2004, 350:1746-1751. This article summarizes our current state of knowledge of asymptomatic primary hyperparathyroidism and how this knowledge translates into practical approaches to the patient.
    • (2004) N Engl J Med , vol.350 , pp. 1746-1751
    • Bilezikian, J.P.1    Silverberg, S.J.2
  • 68
    • 1542269634 scopus 로고    scopus 로고
    • Marked and sustained increase in bone density after parathyroidectomy in patients with primary hyperparathyroidism; a six-year longitudinal study with or without parathyroidectomy in a Japanese population
    • Nomura R, Sugimoto T, Tsukamoto R, et al.: Marked and sustained increase in bone density after parathyroidectomy in patients with primary hyperparathyroidism; a six-year longitudinal study with or without parathyroidectomy in a Japanese population. Clin Endocrinol (Oxf) 2004, 60:335-342. After parathyroid surgery, bone density improves, as shown now for a Japanese population.
    • (2004) Clin Endocrinol (Oxf) , vol.60 , pp. 335-342
    • Nomura, R.1    Sugimoto, T.2    Tsukamoto, R.3
  • 69
    • 0000373672 scopus 로고
    • The effect of parathyroidectomy on the recurrence of nephrolithiasis
    • Deaconson TF, Wilson SD, Lemann J: The effect of parathyroidectomy on the recurrence of nephrolithiasis. Surgery 1987, 215:241-251.
    • (1987) Surgery , vol.215 , pp. 241-251
    • Deaconson, T.F.1    Wilson, S.D.2    Lemann, J.3
  • 70
    • 0042878414 scopus 로고    scopus 로고
    • Cohort study on effects of parathyroid surgery on multiple outcomes in primary hyperparathyroidism
    • Vestergaard P, Mosekilde L: Cohort study on effects of parathyroid surgery on multiple outcomes in primary hyperparathyroidism. BMJ 2003, 327:530-534. From a large data set, this paper describes outcomes of parathyroid surgery that have not elusive.
    • (2003) BMJ , vol.327 , pp. 530-534
    • Vestergaard, P.1    Mosekilde, L.2
  • 71
    • 1642580744 scopus 로고    scopus 로고
    • Parathyroid surgery is associated with a decreased risk of hip and upper arm fractures in primary hyperparathyroidism: A controlled cohort study
    • Vestergaard P, Mosekilde L: Parathyroid surgery is associated with a decreased risk of hip and upper arm fractures in primary hyperparathyroidism: a controlled cohort study. J Intern Med 2004, 255:108-118. Also from the Danish data set, this paper illustrates the reduction in risk of surgery after successful parathyroid surgery. The patients referred for surgery appear to have more active primary hyperparathyroidism. Whether these results would be applicable to a population with milder primary hyperparathyroidism cannot be determined from this study.
    • (2004) J Intern Med , vol.255 , pp. 108-118
    • Vestergaard, P.1    Mosekilde, L.2
  • 72
    • 0033592750 scopus 로고    scopus 로고
    • Primary hyperparathyroidism: 10-year course with or without parathyroid surgery
    • Silverberg SJ, Shane E, Jacobs TP, et al.: Primary hyperparathyroidism: 10-year course with or without parathyroid surgery. N Engl J Med 1999, 341:1249-1255.
    • (1999) N Engl J Med , vol.341 , pp. 1249-1255
    • Silverberg, S.J.1    Shane, E.2    Jacobs, T.P.3
  • 73
    • 0025751585 scopus 로고
    • Asymptomatic primary hyperparathyroidism discovered by multichannel biochemical screening: Clinical course and considerations bearing on the need for surgical intervention
    • Parfitt AM, Rao DS, Kleerekoper M: Asymptomatic primary hyperparathyroidism discovered by multichannel biochemical screening: clinical course and considerations bearing on the need for surgical intervention. J Bone Miner Res 1991, 6(suppl 2):S97-S101.
    • (1991) J Bone Miner Res , vol.6 , Issue.SUPPL. 2
    • Parfitt, A.M.1    Rao, D.S.2    Kleerekoper, M.3
  • 74
    • 0023802054 scopus 로고    scopus 로고
    • Effect of lowering dietary calcium intake on fractional whole body calcium retention
    • Dawson-Hughes B, Stern DT, Shipp CC, et al.: Effect of lowering dietary calcium intake on fractional whole body calcium retention. J Clin Endocrinol Metab 1998, 67:62-68.
    • (1998) J Clin Endocrinol Metab , vol.67 , pp. 62-68
    • Dawson-Hughes, B.1    Stern, D.T.2    Shipp, C.C.3
  • 75
    • 0027390226 scopus 로고
    • Effects of calcium restriction on metabolic characteristics of premenopausal women
    • Barger-Lux MJ, Heaney RP: Effects of calcium restriction on metabolic characteristics of premenopausal women. J Clin Endocrinol Metab 1993, 76:103-107.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 103-107
    • Barger-Lux, M.J.1    Heaney, R.P.2
  • 76
    • 0022394754 scopus 로고
    • Sensitivity of the parathyroid hormone-1,25-dihydroxyvitamin D axis to variations in calcium intake in patients with primary hyperparathyroidism
    • Insogna KL, Mitnick ME, Stewart AF, et al.: Sensitivity of the parathyroid hormone-1,25-dihydroxyvitamin D axis to variations in calcium intake in patients with primary hyperparathyroidism. N Engl J Med 1985, 313:1126-1130.
    • (1985) N Engl J Med , vol.313 , pp. 1126-1130
    • Insogna, K.L.1    Mitnick, M.E.2    Stewart, A.F.3
  • 77
    • 0030802040 scopus 로고    scopus 로고
    • Optimal dietary calcium intake in primary hyperparathyroidism
    • Locker FG, Silverberg SJ, Bilezikian JP: Optimal dietary calcium intake in primary hyperparathyroidism. Am J Med 1997, 102:543-550.
    • (1997) Am J Med , vol.102 , pp. 543-550
    • Locker, F.G.1    Silverberg, S.J.2    Bilezikian, J.P.3
  • 78
    • 0036841059 scopus 로고    scopus 로고
    • The role of estrogens and related compounds in the management of primary hyperparathyroidism
    • Marcus R: The role of estrogens and related compounds in the management of primary hyperparathyroidism. J Bone Min Res 2002, 17(suppl 2):N146-N149.
    • (2002) J Bone Min Res , vol.17 , Issue.SUPPL. 2
    • Marcus, R.1
  • 79
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women. Principal results from the Women's Health Initiative Randomized Controlled Trial
    • Writing Group for the Women's Health Initiative Investigators
    • Writing Group for the Women's Health Initiative Investigators: Risks and benefits of estrogen plus progestin in healthy postmenopausal women. Principal results from the Women's Health Initiative Randomized Controlled Trial. JAMA 2002, 228:321-333.
    • (2002) JAMA , vol.228 , pp. 321-333
  • 80
    • 0037339050 scopus 로고    scopus 로고
    • Raloxifene lowers serum calcium and markers of bone turnover in postmenopausal women with primary hyperparathyroidism
    • Rubin MA, Lee KH, McMahon DJ, et al.: Raloxifene lowers serum calcium and markers of bone turnover in postmenopausal women with primary hyperparathyroidism. J Clin Endocrinol Metab 2003, 88:1174-1178. In the wake of the Women's Health Initiative, the reluctance to use estrogens is pervasive, including its potential use in the conservative management of primary hyperparathyroidism. In this article, Rubin et al. show in concept that the selective estrogen receptor modulator raloxifene can lower the serum calcium and bone markers in primary hyperparathyroidism.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1174-1178
    • Rubin, M.A.1    Lee, K.H.2    McMahon, D.J.3
  • 81
    • 0019466374 scopus 로고
    • Effects of dichloromethylene diphosphonate on serum and urinary calcium in primary hyperparathyroidism
    • Shane E, Baquiran DC, Bilezikian JP: Effects of dichloromethylene diphosphonate on serum and urinary calcium in primary hyperparathyroidism. Ann Intern Med 1981, 95:23-27.
    • (1981) Ann Intern Med , vol.95 , pp. 23-27
    • Shane, E.1    Baquiran, D.C.2    Bilezikian, J.P.3
  • 82
    • 0035205387 scopus 로고    scopus 로고
    • Alendronate therapy of primary hyperparathyroidism
    • Hassani S, Braunstein GD, Seibel MJ, et al.: Alendronate therapy of primary hyperparathyroidism. Endocrinologist 2001, 11:459-464.
    • (2001) Endocrinologist , vol.11 , pp. 459-464
    • Hassani, S.1    Braunstein, G.D.2    Seibel, M.J.3
  • 83
    • 0035163394 scopus 로고    scopus 로고
    • Effects of oral alendronate in elderly patients with osteoporosis and mild primary hyperparathyroidism
    • Rossini M, Gatti D, Isaia G, et al.: Effects of oral alendronate in elderly patients with osteoporosis and mild primary hyperparathyroidism. J Bone Miner Res 2001, 16:113-119.
    • (2001) J Bone Miner Res , vol.16 , pp. 113-119
    • Rossini, M.1    Gatti, D.2    Isaia, G.3
  • 84
    • 0036776242 scopus 로고    scopus 로고
    • Alendronate in the treatment of primary hyperparathyroid-related osteoporosis: A 2-year study
    • 82b Parker CR, Blackwell PJ, Faibairn KJ, et al.: Alendronate in the treatment of primary hyperparathyroid-related osteoporosis: a 2-year study. J Clin Endocrinol Metab 2002, 87:4482-4489.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4482-4489
    • Parker, C.R.1    Blackwell, P.J.2    Faibairn, K.J.3
  • 85
    • 0037328653 scopus 로고    scopus 로고
    • Oral alendronate increases bone mineral density in postmenopausal women with primary hyperparathyroidism
    • Chow CC, Chan WB, Li JKY, et al.: Oral alendronate increases bone mineral density in postmenopausal women with primary hyperparathyroidism. J Clin Endocrinol Metab 2003, 88:581-587. This study is a well-designed, randomized clinical trial of alendronate in primary hyperparathyroidism. It is clear that alendronate can increase bone density in this disorder.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 581-587
    • Chow, C.C.1    Chan, W.B.2    Li, J.K.Y.3
  • 86
    • 3242682209 scopus 로고    scopus 로고
    • Alendronate in primary hyperparathyroidism: A double-blind, randomized, placebo-controlled trial
    • Kahn AA, Bilezikiam JP, Kung AWC, et al.: Alendronate in primary hyperparathyroidism: a double-blind, randomized, placebo-controlled trial. J Clin Endocrinol Metab 2004, 89:3319-3325. This is another well-designed, randomized, placebo-controlled clinical trial of alendronate in primary hyperparathyroidism. The study is unique in that it was carried out for 2 years. Alendronate increases bone density but does not alter serum calcium or PTH levels.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3319-3325
    • Kahn, A.A.1    Bilezikiam, J.P.2    Kung, A.W.C.3
  • 87
    • 0027382241 scopus 로고
    • Acute changes in calcium homeostasis during treatment of primary hyperparathyroidism with risedronate
    • Reasner CA, Stone MD, Hosking DJ, et al.: Acute changes in calcium homeostasis during treatment of primary hyperparathyroidism with risedronate. J Clin Endocrinol Metab 1993, 77:1067-1071.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1067-1071
    • Reasner, C.A.1    Stone, M.D.2    Hosking, D.J.3
  • 88
    • 0029051541 scopus 로고
    • Calcium ion sensing cell surface receptors
    • Brown EM, Pollak M, Seidman CE: Calcium ion sensing cell surface receptors. N Engl J Med 1995, 333:234-240.
    • (1995) N Engl J Med , vol.333 , pp. 234-240
    • Brown, E.M.1    Pollak, M.2    Seidman, C.E.3
  • 89
    • 1542708186 scopus 로고    scopus 로고
    • Calcium agonists in hyperparathyroidism
    • Falchetti A: Calcium agonists in hyperparathyroidism. Expert Opin Investig Drugs 2004, 13:229-244. This is a useful review of the current knowledge of calcimimetics in states of excess PTH.
    • (2004) Expert Opin Investig Drugs , vol.13 , pp. 229-244
    • Falchetti, A.1
  • 90
    • 0030667380 scopus 로고    scopus 로고
    • Short term inhibition of parathyroid hormone secretion by a calcium receptor agonist in primary hyperparathyroidism
    • Silverberg SJ, Marriott TB, Bone HG III, et al.: Short term inhibition of parathyroid hormone secretion by a calcium receptor agonist in primary hyperparathyroidism. N Engl J Med 1997, 307:1506-1510.
    • (1997) N Engl J Med , vol.307 , pp. 1506-1510
    • Silverberg, S.J.1    Marriott, T.B.2    Bone III, H.G.3
  • 91
    • 0347362886 scopus 로고    scopus 로고
    • The calcimimetic AMG 073 normalizes serum calcium in patients with primary hyperparathyroidism
    • Shoback DM, Bilezikian JP, Turner SA, et al.: The calcimimetic AMG 073 normalizes serum calcium in patients with primary hyperparathyroidism. J Clin Endocrinol Metab 2003, 88:5644-5649. The calcimimetic cinacalcet is able to reduce the serum calcium to normal in most patients with primary hyperparathyroidism, as shown in this careful study by Shoback et al.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5644-5649
    • Shoback, D.M.1    Bilezikian, J.P.2    Turner, S.A.3


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