In vitro investigation of the hepatic intrinsic clearance of apicidin, a histone deacetylase inhibitor, in mouse, rat, and human, with correction by nonspecific protein binding

Journal of Toxicology and Environmental Health - Part A

Volumn 68, Issue 23-24, 2005, Pages 2207-2218

  Beom, Soo Shin ^a   Eun, Hye Park ^a   Chi, Ho Yoon ^a   Kim, John ^b   Zee, Okpyo ^a   Sun, Dong Yoo ^a  

^a Sungkyunkwan University   (South Korea)

^b LG Chemical Ltd   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

APICIDIN; HISTONE DEACETYLASE;

ALLOMETRY; ANIMAL CELL; ARTICLE; CORRELATION ANALYSIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER CLEARANCE; MICHAELIS MENTEN KINETICS; MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT;

ANIMALS; BLOOD; HISTONE DEACETYLASES; HUMANS; KINETICS; LIVER; MALE; MICE; MICE, INBRED ICR; MICROSOMES, LIVER; PEPTIDES, CYCLIC; PLASMA; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 28744440548     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390500181992     Document Type: Article

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