A comparison of a new oral streptogramin XRP 2868 with quinupristin- dalfopristin against antibiotic-resistant strains of Haemophilus influenzae, Staphylococcus aureus, and Streptococcus pneumoniae

Current Microbiology

Volumn 51, Issue 6, 2005, Pages 363-366

  Mabe, Susan ^a   Champney, W Scott ^a  

^a East Tennessee State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; DALFOPRISTIN PLUS QUINUPRISTIN; STREPTOGRAMIN DERIVATIVE; UNCLASSIFIED DRUG; XRP 2868;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; CELL VIABILITY; HAEMOPHILUS INFLUENZAE; IC 50; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RIBOSOME SUBUNIT; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DRUG COMBINATIONS; DRUG RESISTANCE, BACTERIAL; HAEMOPHILUS INFLUENZAE; RIBOSOMES; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOGRAMIN A; STREPTOGRAMIN B; VIRGINIAMYCIN;

BACTERIA (MICROORGANISMS); HAEMOPHILUS INFLUENZAE; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

EID: 28744438090     PISSN: 03438651     EISSN: 14320991     Source Type: Journal    
DOI: 10.1007/s00284-005-0027-9     Document Type: Article

References (10)

1. Champney WS (2003) Bacterial ribosomal subunit assembly is an antibiotic target. Curr Top Med Chem 3:929-947
2. Champney WS, Burdine R (1998) Macrolide antibiotic inhibition of translation and 50S ribosomal subunit assembly in methicillin-resistant Staphylococcus aureus cells. Microb Drug Resist 4:169-174
3. Champney WS, Mentens N, Zurawick K (2004) An examination of the differential sensitivity to ketolide antibiotics in ermB strains of Streptococcus pneumoniae and Streptococcus pyogenes. Curr Microbiol 49:239-247
4. Champney WS, Tober CL (2000) Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics. Curr Microbiol 41:126-135
5. Champney WS, Tober CL (2003) Preferential inhibition of protein synthesis by ketolide antibiotics in Haemophilus influenzae cells. Curr Microbiol 46:103-108
6. Chu DT, Plattner JJ, Katz L (1996) New directions in antibacterial research. J Med Chem 39:3853-3874
7. Goldstein EJC, Citron DM, Merriam CV, Warren YA, Tyrrell KL, Fernandez HT, Bryskier A (2005) Comparative in vitro activities of XRP2868, pristinamycin, quinupristin-dalfopristin, vancomycin, daptomycin, linezolid, clarithromycin, telithromycin, clindamycin and ampicillin against anerobic gram-positive species, actinomycetes, and lactobacilli. Antimicrob Agents Chemother 49:408-413
8. Lamb HM, Figgitt DP, Faulds D (1999) Quinupristin/dalfopristin. A review of its use in the management of serious Gram-positive infections. Drugs 58:1061-1097
9. Livermore DM (2003) Linezolid in vitro: mechanism and antibacterial spectrum. J Antimicrob Chemother 51:ii9-ii16
10. Pankuch GA, Kelly LM, Lin G, Bryskier A, Couturier C, Jacobs MR, Appelbaum PC (2003) Activities of a new oral streptogramin, XRP 2868, compared to those of other agents against Streptococcus pneumoniae and Haemophilus species. Antimicrob Agents Chemother 47:3270-3274