Antifertility effect of passive administration of antibodies to 80kDa human sperm antigen and its synthetic peptides in male and female rats

American Journal of Reproductive Immunology

Volumn 54, Issue 6, 2005, Pages 332-341

  Bandivdekar, Atmaram H ^a   Vernekar, Vandana J ^a   Kamada, Masaharu ^b   Raghavan, Vijaya P ^a  

^a NATIONAL INSTITUTE FOR RESEARCH IN REPRODUCTIVE HEALTH   (India)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Antibodies; Antisperm antibodies; Fertility; Immunoinfertility; Spermatozoa

Indexed keywords

CONTRACEPTIVE VACCINE; PEPTIDE DERIVATIVE; SPERM ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL AGGLUTINATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FEMALE FERTILITY; IMMUNOBIOLOGY; IMMUNOCONTRACEPTION; MALE; MALE FERTILITY; NONHUMAN; ORGAN SIZE; OVULATION; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; RAT; SPERMATOZOON; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; VAGINA SMEAR;

EID: 28644451828     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/j.1600-0897.2005.00309.x     Document Type: Article

References (28)

1. Aitken RJ: Immunocontraceptive vaccines for human use. J Reprod Immunol 2002; 57:273-287.
2. Anderson DJ, Alexander NJ: A new look at antifertility vaccines. Fertil Steril 1983; 40:557-571.
3. Jones R: Identification and functions of mammalian sperm-egg recognition molecules during fertilization. J Reprod Fertil (Suppl) 1990; 42:89-105.
4. Kerr LE, Paterson M, Aitken RJ: Molecular basis of sperm-egg interaction and the prospects of immunocontraception. J Reprod Immunol 1998; 40:103-118.
5. Primakoff P: Sperm proteins being studied for use in a contraceptive vaccine. Am J Reprod Immunol 1994; 31:208-210.
6. Diekman AB, Herr JC: Sperm antigens and their use in the development of an immunocontraceptive. Am J Reprod Immunol 1997; 37:111-117.
7. Dunbar BS, Munoz MG, Cordle CT, Metz CB: Inhibition of fertilization in vitro by treatment of rabbit spermatozoa with univalent isoantibodies to rabbit sperm hyaluronidase. J Reprod Fertil 1976; 41 381-384.
8. Naz RK, Phillips TM, Rosenblum BB: Characterization of the fertilization antigen-1 for the development of a contraceptive vaccine. Proc Natl Acad Sci USA 1986; 83:5713-5717.
9. Shaha C, Suri A, Talwar GP: Identification of sperm antigens that regulate fertility. Int J Androl 1988; 11:479-491.
10. Shaha C, Suri A, Talwar GP: Induction of fertility in female rats after active immunization with 24 kDa antigen from rat testes. Int J Androl 1990; 13:17-25.
11. Khole VV, Joshi S, Singh S: Identification of epididymis-specific antigens using neonatal tolerization. Am J Reprod Immunol 2000; 44:350-358.
12. Liu QY, Wang LF, Miao SY, Caterall JF: Expression and characterization of a novel human sperm membrane protein. Biol Reprod 1996; 54:323-330.
13. Bandivdekar AH, Koide SS, Sheth AR: Antifertility effects of human sperm antigen in female rats. Contraception 1991; 44:559-569.
14. Bandivdekar AH, Gopalkrishnan K, Garde SV, Fernandez PX, Moodbidri SB, Sheth AR, Koide SS: Antifertility effects in rats actively immunized with 80kDa human semen glycoprotein. Indian J Exp Biol 1992; 30:1017-1023.
15. Bandivdekar AH, Vernekar VJ, Moodbidri SB, Koide SS: Characterization of 80kDa human sperm antigen responsible for immunoinfertility. Am J Reprod Immunol 2001; 45:28-34.
16. Vernekar VJ, Bandivdekar AH, Raghavan VP, Kamada M, Koide SS: Studies with synthetic peptides of 80kDa human sperm antigen. Am J Reprod Immunol 2004; 51:106-111.
17. Bandivdekar AH, Vernekar VJ, Mruk D, Cheng CY, Koide SS, Moodbidri SB: Partial amino acid sequencing of 80kDa human sperm antigen (80kDa HSA). Arch Androl 2001; 47:227-233.
18. Futaki S, Takai T, Akita T, Kitagawa T: p-Benzyloxybenzyl alcohol resin (Novabiochem) was used for peptide anchors. Tetrahedron 1992; 48:8899-8914.
19. Liu FT, Zinnecker M, Hamaoka T, Katz DH: New procedure for preparation and isolation of conjugates of proteins and a synthetic co-polymer of D-amino acids and immunochemical characterization of such conjugates. Biochemistry 1979; 18:692-697.
20. Heide K, Shwick HG: Salt fractionation of immunoglobulin. In Handbook of Experimental Immunology, Chapter 6, DM Weir (ed.). Oxford, Blackwell Science Publications, 1973, pp 6.1-6.11.
21. Fahey JL, Terry EW: Ion-exchange chromatography and gel filtration. In Handbook of Experimental Immunology, Chapter 7, DM Weir (ed.). Oxford, Blackwell Science Publications, 1973, pp 7.1-7.16.
22. Primakoff P, Woolman-Gamer L, Tung KSK, Myles DG: Reversible contraceptive effect of PH-20 immunization in male pigs. Biol Reprod 1997; 56:1142-1146.
23. Tung KSK, Primakoff P, Woolman-Gamer L, Myles DG: Mechanism of infertility in male guinea-pigs immunized with Sperm PH-20. Biol Reprod 1997; 56:1133-1141.
24. Goldberg E: Lactate dehydrogenase C4 as an immunocontraceptive model. In Gamete Interactions: Prospects for Immunocontraception, NJ Alexander, D Griffin, JM Speiler, GMH Waites (eds). New York, Wiley-Liss, 1990, pp 63-74.
25. O'Hern PA, Bambra CS, Isahakia M, Goldberg E: Reversible contraception in female baboons immunized with a synthetic epitope of sperm specific lactate dehydrogenase. Biol Reprod 1995; 52:331-339.
26. Herr JC, Flickinger CJ, Homyk M, Klotz K, John E: Biological and morphological characterization of the intraacrosomal antigen SP-10 from human sperm. Biol Reprod 1990; 42:181-193.
27. Coonrod SA, Westusin ME, Herr JC: Inhibition of bovine fertilization in vitro by antibodies to SP-10. J Reprod Fertil 1996; 107:287-297.
28. Vanage GR, Mehta PB, Moodbidri SB, Iyer KSN: Effect of immunization with synthetic peptide corresponding to region 1-17 of human seminal plasma inhibin on fertility of male rats. Arch Androl 2000; 44:11-21.