Protein phosphorylation and signal transduction modulation: chemistry perspectives for small-molecule drug discovery.

Medicinal chemistry

Volumn 1, Issue 3, 2005, Pages 293-319

  Sawyer, T K ^a   Shakespeare, W C ^a   Wang, Y ^a   Sundaramoorthi, R ^a   Huang, W S ^a   Metcalf 3rd , C A ^a   Thomas, M ^a   Lawrence, B M ^a   Rozamus, L ^a   Noehre, J ^a   Zhu, X ^a   Narula, S ^a   Bohacek, R S ^a   Weigele, M ^a   Dalgarno, D C ^a  

^a ARIAD PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN; PROTEIN KINASE; PROTEIN KINASE INHIBITOR;

CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; METABOLISM; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; ENZYME INHIBITORS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 28644449077     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/1573406053765486     Document Type: Review

References (281)