Role of 4-hydroxynonenal in the hemozoin-mediated inhibition of differentiation of human monocytes to dendritic cells induced by GM-CSF/IL-4

BioFactors

Volumn 24, Issue 1-4, 2005, Pages 283-289

  Skorokhod, Oleksii ^a   Schwarzer, Evelin ^a   Grune, Tilman ^b   Arese, Paolo ^a,c  

^a UNIVERSITY OF TURIN   (Italy)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c Dipartimento di Genetica   (Italy)

Author keywords

4 HNE; 4 hydroxynonenal; Dendritic cells; Hemozoin; Malaria

Indexed keywords

4 HYDROXYNONENAL; ANTIBODY; CD40 ANTIGEN; CD83 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; HEMOZOIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE ANTIGEN; T6 ANTIGEN;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE; CONTROLLED STUDY; DENDRITIC CELL; DERIVATIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; MALARIA; MONOCYTE; PRIORITY JOURNAL; UPREGULATION;

EID: 28644441609     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520240133     Document Type: Article

References (16)

1. E. Schwarzer, H. Kuhn, E. Valente and P. Arese, Malaria-parasitized erythrocytes and hemozoin nonenzymatically generate large amounts of hydroxy fatty acids that inhibit monocyte functions, Blood 101 (2003), 722-728.
2. R.J. Schaur, Basic aspects of the biochemical reactivity of 4-hydroxynonenal, Mol Aspects Med 24 (2003), 149-159.
3. K. Uchida, L.I. Szweda, H.Z. Chae and E.R. Stadtman, Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes, Proc Natl Acad Sci USA 90 (1993), 8742-8746.
4. G. Poli and R.J. Schaur, 4-Hydroxynonenal in the pathomechanism of oxidative stress, IUBMB Life 50 (2000), 315-321.
5. E. Schwarzer, O. Muller, P. Arese, W.G. Siems and T. Grune, Increased levels of 4-hydroxynonenal in human monocytes fed with malarial pigment hemozoin. A possible clue for hemozoin toxicity, FEBS Lett 388 (1996), 119-122.
6. O.A. Skorokhod, M. Alessio, B. Mordmuller, P. Arese and E. Schwarzer, Hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells. A peroxisome proliferator-activated receptor-gamma-mediated effect, J Immunol 173 (2004), 14066-14074.
7. E. Schwarzer, F. Turrini, D. Ulliers, G. Giribaldi, H. Ginsburg and P. Arese, Impairment of macrophage functions after ingestion of plasmodium falciparum-infected erythrocytes or isolated malarial pigment, J. Exp. Med. 176 (1992), 1033-1041.
8. G. Corte, F. Calabi, G. Damiani, A. Bargellesi, R. Tosi and R. Sorrentino, Human Ia molecules carrying DC1 determinants differ in both alpha- and beta-subunits from Ia molecules carrying DR determinants, Nature 292 (1981), 357-360.
9. N. Zarkovic, 4-hydroxynonenal as a bioactive marker of pathophysiological processes, Mol Aspects Med 24 (2003), 281-291.
10. S.W. Luckey, M. Taylor, B.P. Sampey, R.I. Scheinman and D.R. Petersen, 4-hydroxynonenal decreases interleukin-6 expression and protein production in primary rat Kupffer cells by inhibiting nuclear factor-kappaB activation, J Pharmacol Exp Therapeutics 302 (2002), 296-303.
11. H. Esterbauer, R.J. Schaur and H Zollner, Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes, Free Radic Biol Med 11 (1991), 81-128.
12. K. Muller, S.J. Hardwick, C.E. Marchant, N.S. Law, G. Waeg, H. Esterbauer, K.L.H. Carpenter and M.J. Mitchinson, Cytotoxic and chemotactic potencies of several aldehydic components of oxidised low density lipoprotein for human monocyte-macrophages, FEBS Lett 388 (1996), 165-168.
13. M. Dabusti, B. Castagnari, S. Moretti, L. Ferrari, A. Tieghi and F. Lanza, CD116 (granulocyte-macrophage colony stimulating factor receptor), J Biol Regul Homeost Agents 15 (2001), 86-89.
14. I. Escargueil-Blanc, R. Salvayre, N. Vacaresse, G. Jurgens, B. Darblade, J.F. Arnal, S. Parthasarathy and A. Negre-Salvayre, Mildly oxidized LDL induces activation of platelet-derived growth factor beta-receptor pathway, Circulation 104 (2001), 1814-1821.
15. I. Suc, O. Meilhac, I. Lajoie-Mazenc, J. Vandaele, G. Jurgens, R. Salvayre and A. Negre-Salvayre, Activation of EGF receptor by oxidized LDL, FASEB J 12 (1998), 665-671.
16. Y. Shin, B.H. White, M. Uh and A. Sidhu, Modulation of D1-like dopamine receptor function by aldehydic products of lipid peroxidation, Brain Res 968 (2003), 102-113.