Alveolar bone loss and aging: A model for the study in mice

Journal of Periodontology

Volumn 76, Issue 11, 2005, Pages 1966-1971

  Rivaldo, Elken Gomes ^a,b   Padilha, Dalva P ^a,c   Hugo, Fernando N ^d  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Aging; Alveolar bone loss; Mice; Resorption

Indexed keywords

TOLONIUM CHLORIDE;

AGING; ALVEOLAR BONE; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPUTER ANALYSIS; CONTROLLED STUDY; FEMALE; IMAGE ANALYSIS; MALE; MANDIBLE RESECTION; MOUSE; NONHUMAN; OSTEOLYSIS; OSTEOPENIA; PERIOSTEUM GRAFT; STAINING; STATISTICAL SIGNIFICANCE; STUDENT T TEST;

AGING; ALVEOLAR BONE LOSS; ALVEOLAR PROCESS; ANIMALS; DENTAL CEMENTUM; DENTAL ENAMEL; DISEASE MODELS, ANIMAL; FEMALE; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MANDIBLE; MICE; PHOTOGRAPHY; SEX FACTORS; SURGICAL FLAPS; TOOTH CERVIX; TOOTH ROOT;

EID: 28644440055     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2005.76.11.1966     Document Type: Article

References (33)

1. Belting CM, Schour I, Weinmann JP, Shepro MJ. Age changes in the periodontal tissues of the rat molar. J Dent Res 1953;32:332-353.
2. Amstad-Jossi M, Schroeder HE. Age-related alterations of periodontal structures around the cemento-enamel junction and of the gingival connective tissue composition in germ-free rats. J Periodontal Res 1978; 13:76-90.
3. Messer HH. Alveolar bone loss in a strain of mice. J Periodontal Res 1980;15:193-205.
4. Sashima M, Satoh M, Suzuki A. Alveolar bone loss of senescence-accelerated mouse (SAM). J Dent Res 1990;69:82-86.
5. Barnett NA, Rowe DJ. A comparison of alveolar bone in young and aged mice. J Periodontol 1986;57:447-452.
6. Yaffe A, Fine N, Binderman I. Regional accelerated phenomenon in the mandible following mucoperiosteal flap surgery. J Periodontol 1994;65:79-83.
7. Yaffe A, Fine N, Alt I, Binderman I. The effect of bisphosphonate on alveolar bone resorption following mucoperiosteal flap surgery in the mandible of rats. J Periodontol 1995;66:999-1003.
8. Yaffe A, Iztkovich M, Earon Y, Alt I, Lilov R, Binderman I. Local delivery of an amino bisphosphonate prevents the resorptive phase of alveolar bone following mucoperiosteal flap surgery in rats. J Periodontol 1997;68: 884-889.
9. Yaffe A, Binderman I, Breuer E, Pinto T, Golomb G. Disposition of alendronate following local delivery in a rat jaw. J Periodontol 1999;70:893-895.
10. Yaffe A, Golomb G, Breuer E, Binderman I. The effect of topical delivery of novel bisacylphosphonates in reducing alveolar bone loss in the rat model. J Periodontol 2000;71:1607-1612.
11. Yaffe A, Kollerman R, Bahar H, Binderman I. The influence of alendronate on bone formation and resorption in a rat ectopic bone development model. J Periodontol 2003;74:44-50.
12. Yaffe A, Herman A, Bahar H, Binderman I. Combined local application of tetracycline and bisphosphonate reduces alveolar bone resorption in rats. J Periodontol 2003;74:1038-1042.
13. Binderman I, Adut M, Yaffe A. Effectiveness of local delivery of alendronate in reducing alveolar bone loss following periodontal surgery in rats. J Periodontol 2000;71:1236-1240.
14. Binderman I, Adut M, Zohar R, Bahar H, Faibish D, Yaffe A. Alveolar bone resorption following coronal versus apical approach in a mucoperiosteal flap surgery procedure in the rat mandible. J Periodontol 2001;72:1348-1353.
15. Kaynak D, Meffert R, Gunhan M, Gunhan O, Ozkaya O. A histopathological investigation on the effects of the bisphosphonate alendronate on resorptive phase following mucoperiosteal flap surgery in the mandible of rats. J Periodontol 2000;71:790-796.
16. Kaynak D, Meffert R, Bostanci H, Gunhan O, Ozkaya OG. A histopathological investigation on the effect of systemic administration of the bisphosphonate alendronate on resorptive phase following mucoperiosteal flap surgery in the rat mandible. J Periodontol 2003; 74:1348-1354.
17. Grevstad HJ. Doxycycline prevents root resorption and alveolar bone loss in rats after periodontal surgery. Scand J Dent Res 1993;101:287-291.
18. Grevstad HJ, Boe OE. Effect of doxycycline on surgically induced osteoclast recruitment in the rat. Eur J Oral Sci 1995;103:156-159.
19. Frost MH. The biology of fracture healing: An overview for clinicians. Part I. Clin Orthop Relat Res 1989; 248:283-293.
20. Frost MH. The biology of fracture healing: An overview for clinicians. Part II. Clin Orthop Relat Res 1989; 248:294-309.
21. Roberts WE, Turley PK, Brezniak N, Fielder PJ. Implants: Bone physiology and metabolism. CDA J 1987;15:54-61.
22. Roberts WE. Bone tissue interface. J Dent Educ 1988;52:804-809.
23. Tanaka M, Ejiri S, Toyooka E, Kohno S, Ozawa H. Effects of ovariectomy on trabecular structures of rat alveolar bone. J Periodontal Res 2002;37:161-165.
24. Shoji K, Ohtsuka-Isoya M, Horiuchi H, Shinoda H. Bone mineral density of alveolar bone in rats during pregnancy and lactation. J Periodontol 2000;71: 1073-1078.
25. Tatakis DN, Guglielmoni P. HLA-B27 transgenic rats are susceptible to accelerated alveolar bone loss. J Periodontol 2000;71:1395-1400.
26. Al-Rasheed A, Scheerens H, Rennick DM, Fletcher HM, Tatakis DN. Accelerated alveolar bone loss in mice lacking interleukin-10. J Dent Res 2003;82:632-635.
27. May NY, Tatakis DN. Accelerated alveolar bone loss in male HLA-B27 transgenic rats: Adult onset. J Periodontal Res 2004;39:33-36.
28. Moriya Y, Ito K, Murai S. Effects of experimental osteoporosis on alveolar bone loss in rats. J Oral Sci 1998;40:171-175.
29. Hilgert JB, Hugo FN, Bozzetti MC, Padilha DMP. Comparison of two techniques for measuring alveolar bone loss in mice (in Portuguese). Pesqui Odontol Bras 2002;16:216.
30. Brookbank JW. Aging in mammals. In: Brookbank JW, ed. The Biology of Aging. New York: Harper and Row; 1990:40-61.
31. Jordan HV. Rodent model systems in periodontal disease research. J Dent Res 1971;50:236-242.
32. Gilmore ND, Glickman I. Some age changes in the periodontium of the albino mouse. J Dent Res 1959; 38:1195-1206.
33. Shearer GM. Th1/Th2 changes in aging. Mech Ageing Dev 1997;94:1-5.