Inhibition of acute nociceptive responses in rat spinal cord by a bradykinin B1 receptor antagonist

European Journal of Pharmacology

Volumn 527, Issue 1-3, 2005, Pages 44-51

  Conley, Rachel K ^a   Wheeldon, Alan ^a   Webb, Janine K ^a   DiPardo, Robert M ^b   Homnick, Carl F ^b   Bock, Mark G ^b   Chen, Tsing Bau ^b   Chang, Raymond S L ^b   Pettibone, Douglas J ^b   Boyce, Susan ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

(Rat); Antinociception; Bradykinin B1 receptor; Spinal cord

Indexed keywords

3 (3,4 DICHLOROPHENYL) N [1 [4 (4,5 DIHYDRO 1H IMIDAZOL 2 YL)BENZYL] 2 OXO 2 PYRROLIDIN 1 YLETHYL] 3 [(2 NAPHTHYLSULFONYL)AMINO]PROPANAMIDE; BRADYKININ B1 RECEPTOR; BRADYKININ B1 RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HEAT; IN VIVO STUDY; LATENT PERIOD; MALE; MOTOR PERFORMANCE; NERVE CELL; NOCICEPTION; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; ROTAROD TEST; SPINAL CORD; SPINAL CORD DORSAL HORN; THERMAL STIMULATION; WITHDRAWAL REFLEX;

AMIDES; ANIMALS; CARRAGEENAN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; FOOT; HEAT; HINDLIMB; HYPERALGESIA; HYPERSENSITIVITY; INJECTIONS, INTRAVENOUS; INJECTIONS, SPINAL; MALE; MORPHINE; NAPHTHALENES; NOCICEPTORS; PAIN MEASUREMENT; PSYCHOMOTOR PERFORMANCE; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, BRADYKININ B1; SPINAL CORD;

EID: 28544452428     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.06.057     Document Type: Article

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