Substrate-induced conformational changes of the mitochondrial oxoglutarate carrier: A spectroscopic and molecular modelling study

Molecular Membrane Biology

Volumn 22, Issue 5, 2005, Pages 443-452

  Della Rocca, Blasco Morozzo ^a   Miniero, Daniela V ^b   Tasco, Gianluca ^c   Dolce, Vincenza ^b,d   Falconi, Mattia ^a   Ludovico, Anna ^b   Cappello, Anna R ^b,d   Sanchez, Paloma ^a   Stipani, Italo ^b   Casadio, Rita ^c   Desideri, Alessandro ^a   Palmieri, Ferdinando ^b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF BARI   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Conformational changes; Mitochondria; Molecular modelling; Oxoglutarate carrier; Transport; Tryptophan fluorescence

Indexed keywords

ARGININE; CYSTEINE; LEUCINE; OXOGLUTARATE DEHYDROGENASE; THIOL DERIVATIVE; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME CONFORMATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; FLUORESCENCE SPECTROSCOPY; MITOCHONDRIAL MEMBRANE; MOLECULAR MODEL; PHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN TRANSPORT; VALIDATION PROCESS;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; HUMANS; KETOGLUTARIC ACIDS; LYSINE; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SPECTROMETRY, FLUORESCENCE; TRYPTOPHAN; TYROSINE;

EID: 28544449567     PISSN: 09687688     EISSN: 14645203     Source Type: Journal    
DOI: 10.1080/09687860500269335     Document Type: Article

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