Sustained upregulation of inflammatory chemokine and its receptor in aneurysmal and occlusive atherosclerotic disease: Results from tissue analysis with cDNA macroarray and real-time reverse transcriptional polymerase chain reaction methods

Circulation Journal

Volumn 69, Issue 12, 2005, Pages 1490-1495

  Yamagishi, Masakazu ^a,f   Higashikata, Takeo ^b   Ishibashi Ueda, Hatsue ^c   Sasaki, Hiroaki ^d   Ogino, Hitoshi ^d   Iihara, Koji ^e   Miyamoto, Susumu ^e   Nagaya, Noritoshi ^f   Tomoike, Hitonobu ^a   Sakamoto, Aiji ^b  

^a Division of Infection Control and Prevention   (Japan)

^b Division of Biotechnology in Bioscience   (Japan)

^c National Cerebral and Cardiovascular Center   (Japan)

^d Division of Cardiovascular Surgery   (Japan)

^e Division of Neurosurgery   (Japan)

^f NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Aneurysm; Atherosclerosis; CCR 2; Chemokines; CXCR 2; Interleukin 8

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CCR2;

ABDOMINAL AORTA ANEURYSM; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DENSITOMETRY; DNA MICROARRAY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOLECULAR PROBE; PERIPHERAL OCCLUSIVE ARTERY DISEASE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

AGED; AORTIC ANEURYSM, ABDOMINAL; ARTERIAL OCCLUSIVE DISEASES; ARTERIOSCLEROSIS; CHEMOKINES; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INFLAMMATION; INTERLEUKIN-8; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, CHEMOKINE; RECEPTORS, INTERLEUKIN-8B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE ARRAY ANALYSIS; UP-REGULATION;

EID: 28544448468     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.69.1490     Document Type: Article

References (29)

1. Libby P. Inflammation in atherosclerosis. Nature 2002; 420: 868 - 874.
2. Higashikata T, Yamagishi M, Sasaki H, Minatoya K, Ogino H, Ishibashi-Ueda H, et al. Application of real-time RT-PCR to quantifying gene expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human abdominal aortic aneurysm. Atherosclerosis 2004; 177: 353 - 360.
3. Higashikata T, Yamagishi M, Higashi T, Nagata I, Iihara K, Miyamoto S, et al. Altered expression balance of matrix metalloproteinases and their inhibitors in human carotid plaque disruption: Results of quantitative tissue analysis using real-time RT-PCR method. Atherosclerosis 2005 July 20; [Epub ahead of print].
4. Boring L, Gosling J, Cleary M. Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 1998; 394: 894 - 897.
5. Ito T, Ikeda U. Inflammatory cytokines and cardiovascular disease. Curr Drug Targets Inflamm Allergy 2003; 2: 257 - 265.
6. Kusamo KF, Nakamura K, Kusano H, Nishii N, Banba K, Ikeda T, et al. Significance of the level of monocyte chemoattractant protein-1 in human atherosclerosis. Circ J 2004; 68: 671 - 676.
7. Koch AE, Kunkel SL, Pearce WH, Shah MR, Parikh D, Evanoff HL, et al. Enhanced production of the chemotactic cytokines interleukin-8 and monocyte chemoattractant protein-1 in human abdominal aortic aneurysms. Am J Pathol 1993; 142: 1423 - 1431.
8. Yamagishi M, Higashikata T, Higashi T, Nagata I, Ishibashi-Ueda H, Tomoike H, et al. Sustained upregulation of chemokine and its receptor genes associated with matrix metalloproteinase overexpression in human carotid plaque rupture: Results from a quantitative study with real-time RT-PCR method (abstract). J Am Coll Cardiol 2004; 43(Suppl A): 497A.
9. Faber BC, Cleutjens KB, Niessen RL, Aarts PL, Boon W, Greenberg AS, et al. Identification of genes potentially involved in rupture of human atherosclerotic plaques. Circ Res 2001; 89: 547 - 554.
10. Matsushima K, Oppenheim JJ. Interleukin 8 and MCAF: Novel inflammatory cytokines inducible by IL-1 and TNF. Cytokine 1989; 1: 2-13.
11. Boisvert WA, Curtiss LK, Terkeltaub RA. Interleukin-8 and its receptor CXCR2 in atherosclerosis. Immunol Res 2000; 21: 129 - 137.
12. Yound JL, Libby P, Schonbeck U. Cytokines in the pathogenesis of atherosclerosis. Thromb Haemost 2002; 88: 554 - 567.
13. Hansson GK, Libby P, Schonbeck U, Yan ZQ. Innate and adaptive immunity in the pathogenesis of atherosclerosis. Circ Res 2002; 91: 281 - 291.
14. Boisvert WA, Santiago R, Curtiss LK. A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice. J Clin Invest 1998; 101: 353 - 363.
15. Simonini A, Moscucci M, Muller DW, Bates ER, Pagani FD, Burdick MD. IL-8 is an angiogenic factor in human coronary atherectomy tissue. Circulation 2000; 101: 1519 - 1526.
16. Chakrabarti S, Patel KD. Regulation of matrix metalloproteinase-9 release from IL-8-stimulated human neutrophils. J Leukoc Biol 2005; 78: 279 - 288.
17. Pruijt JF, Verzaal P, van Os R, de Kruijf EJ, van Schie ML, Mantovani A, et al. Neutrophils are indispensable for hematopoietic stem cell mobilization induced by interleukin-8 in mice. Proc Natl Acad Sci USA 2002; 99: 6228 - 6233.
18. Funayama H, Ishikawa SE, Kubo N, Katayama T, Yasu T, Saito M, et al. Increases in interleukin-6 and matrix metalloproteinase-9 in the infarct-related coronary artery of acute myocardial infarction. Circ J 2004; 68: 451 - 454.
19. Higo S, Uematsu M, Yamagishi M, Ishibashi-Ueda H, Awata M, Morozumi T, et al. Elevation of plasma matrix metalloproteinase-9 in the culprit coronary artery in patients with acute myocardial infarction: Clinical evidence from distal protection. Circ J 2005; 69: 1180 - 1185.
20. Moreau M, Brocheriou I, Petit L, Ninio E, Chapman MJ, Rouis M. Interleukin-8 mediates downregulation of tissue inhibitor of metalloproteinase-1 expression in cholesterol-loaded human macrophages: Relevance to stability of atherosclerotic plaque. Circulation 1999; 99: 420 - 426.
21. Holm T, Damas JK, Holven K, Nordoy I, Brosstad FR, Ueland T, et al. CXC-chemokines in coronary artery disease: Possible pathogenic role of interactions between oxidized low-density lipoprotein, platelets and peripheral blood mononuclear cell. J Thromb Haemost 2003; 1: 257 - 262.
22. Huo Y, Weber C, Forlow SB, Sperandio M, Thatte J, Mack M, et al. The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium. J Clin Invest 2001; 108: 1307 - 1314.
23. Takata M, Urakaze M, Temaru R, Yamazaki K, Nakamura N, Nobata Y. Pravastatin suppresses the interleukin-8 production induced by thrombin in human aortic endothelial cells cultured with high glucose by inhibiting the p44/42 mitogen activated protein kinase. Br J Pharmacol 2001; 134: 753 - 762.
24. Ito T, Ikeda U, Yamamoto K, Shimada K. Regulation of interleukin-8 expression by HMG-CoA reductase inhibitors in human vascular smooth muscle cells. Atherosclerosis 2002; 165: 51 - 55.
25. Lei ZB, Zhang Z, Jing Q, Qin YW, Pei G, Cao BZ, et al. OxLDL upregulates CXCR2 expression in monocytes via scavenger receptors and activation of p38 mitogen-activated protein kinase. Cardiovasc Res 2002; 53: 524 - 532.
26. Nissen SE, Tuzcu EM, Schoenhagen P, Brown BG, Ganz P, Vogel RA, et al. Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: A randomized controlled trial. JAMA. 2004; 291: 1071 - 1080.
27. Cannon CP, Braunwald E, McCabe CH, Rader DJ, Rouleau JL, Belder R, et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 2004; 350: 1495-1504.
28. Wahre T, Damas JK, Gullestad L, Holm AM, Pedersen TR, Arnesen KE, et al. Hydromethylglutaryl coenzyme A reductase inhibitors down-regulate chemokines and chemokine receptors in patients with coronary artery disease. J Am Coll Cardiol 2003; 41: 1460 - 1467.
29. Dol F, Martin G, Staels B, Mares AM, Cazaubon C, Nisato D, et al. Angiotensin AT1 receptor antagonist Irbesrtan decreases lesion size, chemokine expression, and macrophage accumulation in apolipoprotein E-deficient mice. J Cardiovasc Pharmacol 2001; 38: 395 - 405.