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Volumn 36, Issue 11, 2005, Pages 963-969

Long-term outcome of nonmyeloablative allogeneic transplantation in patients with high-risk multiple myeloma

Author keywords

Allogeneic transplantation; Graft versus host disease; Multiple myeloma; Nonmyeloablative transplantation

Indexed keywords

ANTHRACYCLINE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DEXAMETHASONE; FLUDARABINE; IFOSFAMIDE; MELPHALAN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; THALIDOMIDE;

EID: 28544446473     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705161     Document Type: Article
Times cited : (55)

References (44)
  • 1
    • 0032211193 scopus 로고    scopus 로고
    • High-dose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: Up-front or rescue treatment? Results of a multicenter sequential randomized clinical trial
    • Fermand JP, Ravaud P, Chevret S et al. High-dose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: Up-front or rescue treatment? Results of a multicenter sequential randomized clinical trial. Blood 1998; 92: 3131-3136.
    • (1998) Blood , vol.92 , pp. 3131-3136
    • Fermand, J.P.1    Ravaud, P.2    Chevret, S.3
  • 2
    • 8944220233 scopus 로고    scopus 로고
    • A prospective randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma
    • Attal M, Harousseau JL, Stoppa AM et al. A prospective randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. N Engl J Med 1996; 335: 91-97.
    • (1996) N. Engl. J. Med. , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3
  • 3
    • 0037739753 scopus 로고    scopus 로고
    • High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
    • Child JA, Morgan GJ, Davies FE et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003; 348: 1875-1883.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1875-1883
    • Child, J.A.1    Morgan, G.J.2    Davies, F.E.3
  • 4
  • 5
    • 0035024063 scopus 로고    scopus 로고
    • Salvage therapy with thalidomide in multiple myeloma patients relapsing after autologous peripheral blood stem cell transplantation
    • Tosi P, Ronconi S, Zamagni E et al. Salvage therapy with thalidomide in multiple myeloma patients relapsing after autologous peripheral blood stem cell transplantation. Haematologica 2001; 86: 409-413.
    • (2001) Haematologica , vol.86 , pp. 409-413
    • Tosi, P.1    Ronconi, S.2    Zamagni, E.3
  • 6
    • 0033664388 scopus 로고    scopus 로고
    • Treatment approaches for relapsing and refractory multiple myeloma
    • Blade J, Esteve J. Treatment approaches for relapsing and refractory multiple myeloma. Acta Oncol 2000; 39: 843-847.
    • (2000) Acta Oncol. , vol.39 , pp. 843-847
    • Blade, J.1    Esteve, J.2
  • 7
    • 0035895104 scopus 로고    scopus 로고
    • Salvage therapy for multiple myeloma with thalidomide and CED chemotherapy
    • Moehler T, Neben K, Benner A et al. Salvage therapy for multiple myeloma with thalidomide and CED chemotherapy. Blood 2001; 98: 3846-3848.
    • (2001) Blood , vol.98 , pp. 3846-3848
    • Moehler, T.1    Neben, K.2    Benner, A.3
  • 8
    • 5644250621 scopus 로고    scopus 로고
    • A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma
    • Jagannath S, Barlogie B, Berenson J et al. A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma. Br J Haematol 2004; 127: 165-172.
    • (2004) Br. J. Haematol. , vol.127 , pp. 165-172
    • Jagannath, S.1    Barlogie, B.2    Berenson, J.3
  • 9
    • 0032824758 scopus 로고    scopus 로고
    • Prognostic evaluation in multiple myeloma: An analysis of the impact of new prognostic factors
    • Turesson I, Abildgaard N, Ahlgren T et al. Prognostic evaluation in multiple myeloma: An analysis of the impact of new prognostic factors. Br J Haematol 1999; 106: 1005-1012.
    • (1999) Br. J. Haematol. , vol.106 , pp. 1005-1012
    • Turesson, I.1    Abildgaard, N.2    Ahlgren, T.3
  • 10
    • 17344395438 scopus 로고    scopus 로고
    • Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization
    • Zojer N, Konigsberg R, Ackermann J et al. Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization. Blood 2000; 95: 1925-1930.
    • (2000) Blood , vol.95 , pp. 1925-1930
    • Zojer, N.1    Konigsberg, R.2    Ackermann, J.3
  • 11
    • 0035869257 scopus 로고    scopus 로고
    • 2-microglobulin produce a powerful myeloma staging system for patients receiving high dose therapy
    • 2-microglobulin produce a powerful myeloma staging system for patients receiving high dose therapy. Blood 2001; 97: 1566-1571.
    • (2001) Blood , vol.97 , pp. 1566-1571
    • Facon, T.1    Avet-Loiseau, H.2    Guillerm, G.3
  • 12
    • 0037217603 scopus 로고    scopus 로고
    • Prognostic impact of cytogenetic and interphase fluorescence in situ hybridization-defined chromosome 13 deletion in multiple myeloma: Early results of total therapy II
    • Shaughnessy Jr J, Tian E, Sawyer J et al. Prognostic impact of cytogenetic and interphase fluorescence in situ hybridization-defined chromosome 13 deletion in multiple myeloma: Early results of total therapy II. Br J Haemtol 2003; 120: 44-52.
    • (2003) Br. J. Haemtol. , vol.120 , pp. 44-52
    • Shaughnessy Jr., J.1    Tian, E.2    Sawyer, J.3
  • 13
    • 9144259158 scopus 로고    scopus 로고
    • Myeloma management guidelines: A common report from the Scientific Advisors of the International Myeloma Foundation
    • Durie BG, Kyle RA, Belch A et al. Myeloma management guidelines: A common report from the Scientific Advisors of the International Myeloma Foundation. Hematol J 2003; 4: 379-398.
    • (2003) Hematol. J. , vol.4 , pp. 379-398
    • Durie, B.G.1    Kyle, R.A.2    Belch, A.3
  • 14
    • 0034894245 scopus 로고    scopus 로고
    • Allogeneic hematopoietic cell transplantation for multiple myeloma
    • Bensinger WI, Maloney D, Storb R. Allogeneic hematopoietic cell transplantation for multiple myeloma. Semin Hematol 2001; 38: 243-249.
    • (2001) Semin. Hematol. , vol.38 , pp. 243-249
    • Bensinger, W.I.1    Maloney, D.2    Storb, R.3
  • 15
    • 0030043438 scopus 로고    scopus 로고
    • Graft-versus-myeloma effect: Proof of principle
    • Tricot G, Vesole D, Jagannath S et al. Graft-versus-myeloma effect: proof of principle. Blood 1996; 87: 1196-1198.
    • (1996) Blood , vol.87 , pp. 1196-1198
    • Tricot, G.1    Vesole, D.2    Jagannath, S.3
  • 16
    • 0031058106 scopus 로고    scopus 로고
    • Adoptive immunotherapy for relapsed multiple myeloma after allogeneic bone marrow transplantation (BMT): Evidence for a graft versus myeloma effect
    • Bertz H, Burger JA, Kunzmann R et al. Adoptive immunotherapy for relapsed multiple myeloma after allogeneic bone marrow transplantation (BMT): Evidence for a graft versus myeloma effect. Leukemia 1997; 11: 281-283.
    • (1997) Leukemia , vol.11 , pp. 281-283
    • Bertz, H.1    Burger, J.A.2    Kunzmann, R.3
  • 17
    • 0030815867 scopus 로고    scopus 로고
    • Donor leukocyte infusions are effective in relapsed multiple myeloma after allogeneic bone marrow transplantation
    • Lokhorst HM, Schattenberg A, Cornelissen JJ et al. Donor leukocyte infusions are effective in relapsed multiple myeloma after allogeneic bone marrow transplantation. Blood 1997; 90: 4206-4211.
    • (1997) Blood , vol.90 , pp. 4206-4211
    • Lokhorst, H.M.1    Schattenberg, A.2    Cornelissen, J.J.3
  • 18
    • 10544228954 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation vs autologous stem cell transplantation in multiple myeloma: A retrospective case-matched study from the European Group for Blood and Marrow Transplantation
    • Bjorkstrand B, Ljungman P, Svensson H et al. Allogeneic bone marrow transplantation vs autologous stem cell transplantation in multiple myeloma: A retrospective case-matched study from the European Group for Blood and Marrow Transplantation. Blood 1996; 88: 4711-4718.
    • (1996) Blood , vol.88 , pp. 4711-4718
    • Bjorkstrand, B.1    Ljungman, P.2    Svensson, H.3
  • 19
    • 0029822773 scopus 로고    scopus 로고
    • Allogeneic marrow transplantation for multiple myeloma: An analysis of risk factors on outcome
    • Bensinger WI, Buckner CD, Anasetti C et al. Allogeneic marrow transplantation for multiple myeloma: An analysis of risk factors on outcome. Blood 1996; 88: 2787-2793.
    • (1996) Blood , vol.88 , pp. 2787-2793
    • Bensinger, W.I.1    Buckner, C.D.2    Anasetti, C.3
  • 20
    • 0029039069 scopus 로고
    • Prognostic factors in allogeneic bone marrow transplantation for multiple myeloma
    • Gharton G, Tura S, Ljungman P et al. Prognostic factors in allogeneic bone marrow transplantation for multiple myeloma. J Clin Oncol 1995; 13: 1312-1322.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1312-1322
    • Gharton, G.1    Tura, S.2    Ljungman, P.3
  • 21
    • 0033796947 scopus 로고    scopus 로고
    • Second allogeneic transplantation using nonmyeloablative conditioning for patients who relapsed or developed secondary malignancies following autologous transplantation
    • Nagler A, Or R, Naparstek E et al. Second allogeneic transplantation using nonmyeloablative conditioning for patients who relapsed or developed secondary malignancies following autologous transplantation. Exp Hematol 2000; 28: 1096-1104.
    • (2000) Exp. Hematol. , vol.28 , pp. 1096-1104
    • Nagler, A.1    Or, R.2    Naparstek, E.3
  • 22
    • 0031879197 scopus 로고    scopus 로고
    • Transplant-lite: Induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment for lymphoid malignancies
    • Khouri IF, Keating M, Korbling M et al. Transplant-lite: Induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment for lymphoid malignancies. J Clin Oncol 1998; 16: 2817-2824.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2817-2824
    • Khouri, I.F.1    Keating, M.2    Korbling, M.3
  • 23
    • 0032006125 scopus 로고    scopus 로고
    • Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of nonmalignant hematologic diseases
    • Slavin S, Nagler A, Naparstek E et al. Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of nonmalignant hematologic diseases. Blood 1998; 91: 756-763.
    • (1998) Blood , vol.91 , pp. 756-763
    • Slavin, S.1    Nagler, A.2    Naparstek, E.3
  • 24
    • 0034554782 scopus 로고    scopus 로고
    • Autografting followed by nonmyeloablative immunosuppressive chemotherapy and allogeneic peripheral-blood hematopoietic stem-cell transplantation as treatment of resistant Hodgkin's disease and non-Hodgkin's disease
    • Carella AM, Cavaliere M, Lerma E et al. Autografting followed by nonmyeloablative immunosuppressive chemotherapy and allogeneic peripheral-blood hematopoietic stem-cell transplantation as treatment of resistant Hodgkin's disease and non-Hodgkin's disease. J Clin Oncol 2000; 18: 3918-3924.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 3918-3924
    • Carella, A.M.1    Cavaliere, M.2    Lerma, E.3
  • 25
    • 17944382045 scopus 로고    scopus 로고
    • Reduced intensity conditioning: Enhanced graft-versus-tumor effect following dose-reduced conditioning and allogeneic transplantation for refractory lymphoid malignancies
    • Mohty M, Fegueux N, Exbrayat C et al. Reduced intensity conditioning: enhanced graft-versus-tumor effect following dose-reduced conditioning and allogeneic transplantation for refractory lymphoid malignancies. Bone Marrow Transplant 2001; 28: 335-339.
    • (2001) Bone Marrow Transplant. , vol.28 , pp. 335-339
    • Mohty, M.1    Fegueux, N.2    Exbrayat, C.3
  • 27
    • 0035353184 scopus 로고    scopus 로고
    • High response rate in refractory and poor-risk multiple myeloma after allotransplantation using a nonmyeloablative conditioning regimen and donor leukocyte infusions
    • Badros A, Barlogie B, Morris C et al. High response rate in refractory and poor-risk multiple myeloma after allotransplantation using a nonmyeloablative conditioning regimen and donor leukocyte infusions. Blood 2001; 97: 2574-2579.
    • (2001) Blood , vol.97 , pp. 2574-2579
    • Badros, A.1    Barlogie, B.2    Morris, C.3
  • 28
    • 0036682491 scopus 로고    scopus 로고
    • Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma
    • Kroger N, Schwerdtfeger R, Kiehl M et al. Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma. Blood 2002; 100: 755-760.
    • (2002) Blood , vol.100 , pp. 755-760
    • Kroger, N.1    Schwerdtfeger, R.2    Kiehl, M.3
  • 29
    • 0142152420 scopus 로고    scopus 로고
    • Allografting with non-myeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma
    • Maloney DG, Molina AJ, Sahebi F et al. Allografting with non-myeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma. Blood 2003; 102: 3447-3454.
    • (2003) Blood , vol.102 , pp. 3447-3454
    • Maloney, D.G.1    Molina, A.J.2    Sahebi, F.3
  • 30
    • 1842861983 scopus 로고    scopus 로고
    • Graft-versus-myeloma effect following antithymocyte globulin-based reduced intensity conditioning allogeneic stem cell transplantation
    • Mohty M, Boiron JM, Damaj G et al. Graft-versus-myeloma effect following antithymocyte globulin-based reduced intensity conditioning allogeneic stem cell transplantation. Bone Marrow Transplant 2004; 34: 77-84.
    • (2004) Bone Marrow Transplant. , vol.34 , pp. 77-84
    • Mohty, M.1    Boiron, J.M.2    Damaj, G.3
  • 31
    • 0016187133 scopus 로고
    • Clinical manifestations of graft versus host disease in human recipients of marrow from HLA matched sibling donors
    • Glucksberg H, Storb R, Fefer A et al. Clinical manifestations of graft versus host disease in human recipients of marrow from HLA matched sibling donors. Transplantation 1974; 18: 295-304.
    • (1974) Transplantation , vol.18 , pp. 295-304
    • Glucksberg, H.1    Storb, R.2    Fefer, A.3
  • 32
    • 0025860239 scopus 로고
    • Chronic graft-versus-host disease and other late complications of bone marrow transplantation
    • Sullivan KM, Agura E, Anasetti C et al. Chronic graft-versus-host disease and other late complications of bone marrow transplantation. Semin Hematol 1991; 28: 250-259.
    • (1991) Semin. Hematol. , vol.28 , pp. 250-259
    • Sullivan, K.M.1    Agura, E.2    Anasetti, C.3
  • 33
    • 18244428600 scopus 로고    scopus 로고
    • Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and hematopoietic stem cell transplantation
    • Blade J, Samson D, Reece D et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and hematopoietic stem cell transplantation. Br J Haematol 1998; 102: 1115-1123.
    • (1998) Br. J. Haematol. , vol.102 , pp. 1115-1123
    • Blade, J.1    Samson, D.2    Reece, D.3
  • 34
    • 0022712686 scopus 로고
    • Censoring distributions as a measure of follow-up in survival analysis
    • Korn EL. Censoring distributions as a measure of follow-up in survival analysis. Stat Med 1986; 5: 255-260.
    • (1986) Stat. Med. , vol.5 , pp. 255-260
    • Korn, E.L.1
  • 35
    • 33845382806 scopus 로고
    • Non-parametric estimation from incomplete observation
    • Kaplan EL, Meier P. Non-parametric estimation from incomplete observation. J Am Stat Assoc 1958; 47: 457-481.
    • (1958) J. Am. Stat. Assoc. , vol.47 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 36
    • 0001646484 scopus 로고
    • Cox's regression model for counting processes, a large sample study
    • Andersen P, Gill R. Cox's regression model for counting processes, a large sample study. Ann Statist 1982; 10: 1100-1120.
    • (1982) Ann. Statist. , vol.10 , pp. 1100-1120
    • Andersen, P.1    Gill, R.2
  • 37
    • 1842607847 scopus 로고    scopus 로고
    • R Development Core Team R Foundation for Statistical Computing: Vienna Austria (ISBN 3-900051-00-3)
    • R Development Core Team. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing: Vienna, Austria, 2004 (ISBN 3-900051-00-3).
    • (2004) R: A Language and Environment for Statistical Computing
  • 38
    • 0038009391 scopus 로고    scopus 로고
    • Myeloablative intensified conditioning regimen with in vivo T-cell depletion (ATG) followed by allografting in patients with advanced multiple myeloma. A phase I/II study of the German Study-group Multiple Myeloma (DSMM)
    • Kroger N, Einsele H, Wolff D et al. Myeloablative intensified conditioning regimen with in vivo T-cell depletion (ATG) followed by allografting in patients with advanced multiple myeloma. A phase I/II study of the German Study-group Multiple Myeloma (DSMM). Bone Marrow Transplant 2003; 31: 973-979.
    • (2003) Bone Marrow Transplant. , vol.31 , pp. 973-979
    • Kroger, N.1    Einsele, H.2    Wolff, D.3
  • 39
    • 0036892317 scopus 로고    scopus 로고
    • Unrelated stem cell transplantation in multiple myeloma after a reduced-intensity conditioning with pretransplantation antithymocyte globulin is highly effective with low transplantation-related mortality
    • Kroger N, Sayer HG, Schwerdtfeger R et al. Unrelated stem cell transplantation in multiple myeloma after a reduced-intensity conditioning with pretransplantation antithymocyte globulin is highly effective with low transplantation-related mortality. Blood 2002; 100: 3919-3924.
    • (2002) Blood , vol.100 , pp. 3919-3924
    • Kroger, N.1    Sayer, H.G.2    Schwerdtfeger, R.3
  • 40
    • 0036750105 scopus 로고    scopus 로고
    • Fludarabine/melphalan conditioning for allogeneic transplantation in patients with multiple myeloma
    • Giralt S, Aleman A, Anagnostopoulos A et al. Fludarabine/melphalan conditioning for allogeneic transplantation in patients with multiple myeloma. Bone Marrow Transplant 2002; 30: 367-373.
    • (2002) Bone Marrow Transplant. , vol.30 , pp. 367-373
    • Giralt, S.1    Aleman, A.2    Anagnostopoulos, A.3
  • 41
    • 0038015884 scopus 로고    scopus 로고
    • Follow-up of patients with progressive multiple myeloma undergoing allografts after reduced-intensity conditioning
    • Einsele H, Schaefer HJ, Hebart H et al. Follow-up of patients with progressive multiple myeloma undergoing allografts after reduced-intensity conditioning. Br J Haematol 2003; 121: 411-418.
    • (2003) Br. J. Haematol. , vol.121 , pp. 411-418
    • Einsele, H.1    Schaefer, H.J.2    Hebart, H.3
  • 42
    • 0344961159 scopus 로고    scopus 로고
    • Dissociation of putative graft-versus-myeloma effects in patients with rapidly progressive multiple myeloma
    • Luft T, Moos M, Goldschmidt H et al. Dissociation of putative graft-versus-myeloma effects in patients with rapidly progressive multiple myeloma. Br J Haematol 2003; 123: 646-653.
    • (2003) Br. J. Haematol. , vol.123 , pp. 646-653
    • Luft, T.1    Moos, M.2    Goldschmidt, H.3
  • 43
    • 0344511759 scopus 로고    scopus 로고
    • Chronic but not acute graft-versus-host disease improves outcome in multiple myeloma patients after non-myeloablative allogeneic transplantation
    • Perez-Simon JA, Martino R, Alegre A et al. Chronic but not acute graft-versus-host disease improves outcome in multiple myeloma patients after non-myeloablative allogeneic transplantation. Br J Haematol 2003; 121: 104-108.
    • (2003) Br. J. Haematol. , vol.121 , pp. 104-108
    • Perez-Simon, J.A.1    Martino, R.2    Alegre, A.3
  • 44
    • 24244456594 scopus 로고    scopus 로고
    • Influence of timing allogeneic stem cell transplantation after dose-reduced melphalan/fludarabine conditioning in multiple myeloma
    • (abstr. 2694)
    • Kroger N, Perez-Simon J, Myint H et al. Influence of timing allogeneic stem cell transplantation after dose-reduced melphalan/fludarabine conditioning in multiple myeloma. Blood 2003; 102: 728a (abstr. 2694).
    • (2003) Blood , vol.102
    • Kroger, N.1    Perez-Simon, J.2    Myint, H.3


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