Immunolocalization of NFATc4 in the adult mouse brain

Journal of Neuroscience Research

Volumn 82, Issue 6, 2005, Pages 762-770

  Bradley, Katherine C ^a   Groth, Rachel D ^a   Mermelstein, Paul G ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Calcineurin; Hippocampus; Hypothalamus; NFAT; Olfactory bulb; Plasticity

Indexed keywords

PROTEIN SUBUNIT; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC4; UNCLASSIFIED DRUG;

AMYGDALOID NUCLEUS; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CEREBELLUM; CORPUS STRIATUM; GLOBUS PALLIDUS; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNOLOCALIZATION; MALE; MOUSE; NEOCORTEX; NERVE CELL PLASTICITY; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TISSUE DISTRIBUTION;

ANIMALS; BRAIN; DIAGNOSTIC IMAGING; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; NFATC TRANSCRIPTION FACTORS;

EID: 28544433316     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20695     Document Type: Article

References (20)

1. Benedito AB, Lehtinen M, Massol R, Lopes UG, Kirchhausen T, Rao A, Bonni A. 2005. The transcription factor NFAT3 mediates neuronal survival. J Biol Chem 280:2818-2825.
2. Bolanos CA, Nestler EJ. 2004. Neurotrophic mechanisms in drug addiction. Neuromol Med 5:69-83.
3. Carter AR, Chen C, Schwartz PM, Segal RA. 2002. Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure. J Neurosci 22:1316-1327.
4. Charpak S, Mertz J, Beaurepaire E, Moreaux L, Delaney K. 2001. Odor-evoked calcium signals in dendrites of rat mitral cells. Proc Natl Acad Sci U S A 98:1230-1234.
5. 2+, calcineurin, and NF-AT. Cell 96:611-614.
6. Crabtree GR, Olson EN. 2002. NFAT signaling: choreographing the social lives of cells. Cell 109(Suppl):S67-S79.
7. Deisseroth K, Mermelstein PG, Xia H, Tsien RW. 2003. Signaling from synapse to nucleus: the logic behind the mechanisms. Curr Opin Neurobiol 13:354-365.
8. Givalois L, Naert G, Rage F, Ixart G, Arancibia S, Tapia-Arancibia L. 2004. A single brain-derived neurotrophic factor injection modifies hypothalamo-pituitary-adrenocortical axis activity in adult male rats. Mol Cell Neurosci 27:280-295.
9. Graef IA, Mermelstein PG, Stankunas K, Neilson JR, Deisseroth K, Tsien RW, Crabtree GR. 1999. L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons. Nature 401:703-708.
10. Graef IA, Wang F, Charron F, Chen L, Neilson J, Tessier-Lavigne M, Crabtree GR. 2003. Neurotrophins and netrins require calcineurin/ NFAT signaling to stimulate outgrowth of embryonic axons. Cell 113:657-670.
11. Groth RD, Mermelstein PG. 2003. Brain-derived neurotrophic factor activation of NFAT (nuclear factor of activated T-cells)-dependent transcription: a role for the transcription factor NFATc4 in neurotrophin-mediated gene expression. J Neurosci 23:8125-8134.
12. Hyman SE, Malenka RC. 2001. Addiction and the brain: the neurobiology of compulsion and its persistence. Nat Rev Neurosci 2:695-703.
13. Jayanthi S, Deng X, Ladenheim B, McCoy MT, Cluster A, Cai NS, Cadet JL. 2005. Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis. Proc Natl Acad Sci U S A 102:868-873.
14. Liu FC, Graybiel AM. 1996. Spatiotemporal dynamics of CREB phosphorylation: transient vs. sustained phosphorylation in the developing striatum. Neuron 17:1133-1144.
15. Paxinos G, Franklin KBJ. 2001. The mouse brain in stereotaxic coordinates. San Diego: Academic Press.
16. Rao A, Luo C, Hogan PG. 1997. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 15:707-747.
17. Siuciak JA, Wong V, Pearsall D, Wiegand SJ, Lindsay RM. 1995. BDNF produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception. Eur J Neurosci 7:663-670.
18. Tan A, Moratalla R, Lyford GL, Worley P, Graybiel AM. 2000. The activity-regulated cytoskeletal-associated protein arc is expressed in different striosome-matrix patterns following exposure to amphetamine and cocaine. J Neurochem 74:2074-2078.
19. Wilkins BJ, De Windt LJ, Bueno OF, Braz JC, Glascock BJ, Kimball TF, Molkentin JD. 2002. Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth. Mol Cell Biol 22:7603-7613.
20. Wilkins BJ, Dai YS, Bueno OF, Parsons SA, Xu J, Plank DM, Jones F, Kimball TR, Molkentin JD. 2004. Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ Res 94:110-118.