Effects of interleukins 2 and 12 on the levels of granzyme B and perforin and their mRNAs in tributyltin-exposed human natural killer cells

Archives of Toxicology

Volumn 79, Issue 12, 2005, Pages 711-720

  Thomas, LeeShawn D ^a   Shah, Hemangini ^b   Bankhurst, Arthur D ^b   Whalen, Margaret M ^a  

^a TENNESSEE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

Butyltins; Granzyme B; IL 12; IL 2; Perforin

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOTOXIC FACTOR; GRANZYME B; INTERLEUKIN 12; INTERLEUKIN 2; MESSENGER RNA; PERFORIN; TRIBUTYLTIN;

ARTICLE; ENZYME BLOOD LEVEL; HUMAN; HUMAN CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STATISTICAL SIGNIFICANCE; TUMOR CELL;

ADULT; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION; GRANZYMES; HUMANS; INTERLEUKIN-12; INTERLEUKIN-2; K562 CELLS; KILLER CELLS, NATURAL; MALE; MEMBRANE GLYCOPROTEINS; PORE FORMING CYTOTOXIC PROTEINS; RNA, MESSENGER; SERINE ENDOPEPTIDASES; TRIALKYLTIN COMPOUNDS;

EID: 28444493005     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-005-0002-z     Document Type: Article

References (63)

1. Aluoch A, Whalen MM (2005) Tributyltin-induced effects on MAP kinases p38 and p44/42 in human natural killer cells. Toxicology 209:263-277
2. Alzieu C, Sanjuan J, Michel P, Borel M, Dreno JP (1989) Monitoring and assessment of butyltins in Atlantic coastal waters. Mar Pollut 20:22-26
3. Anderson RS, Unger MA, Burreson EM (1996) Enhancement of Perkinsus marinus disease progression in TBT-exposed oysters (Crossostrea virginica). Mar Environ Res 42:177-180
4. Bariagaber AK, Whalen MW (2003) Decreased adenylyl cyclase and cAMP-dependent protein kinase activities inhibit the cytotoxic function of human natural killer cells. Human Immunol 64:866-873
5. Biron CA, Byron KS, Sullivan JL (1989) Severe herpes virus infections in an adolescent without natural killer cells. N Engl J Med 320:1731-1735
6. Cooper EL, Arizza V, Cammarata M, Pellerito L, Parinello (1995) Tributyltin affects phagocytic activity of Ciona intestinalis hemocytes. Comp Biochem Physiol 112C:285-289
7. DeBlaker-Hohe DF, Yamauchi A, Yu CR, Horvath-Arcidiacono JA, and Bloom ET (1995) IL-12 synergizes with IL-2 to induce lymphokine-activated cytotoxicity and perforin and granzyme gene expression in fresh human NK cells. Cell Immunol 165:33-43
8. Djeu JY, Jiang K, Wei S (2002) A view to a kill: signals triggering cytotoxicity. Clin Cancer Res 8:636-640
9. Dokur M, Boyadjieva NI, Sarkar DK (2003) Reduction of perforin, granzyme B, and cytokine interferon γ by ethanol in male fisher 344 rats. Alcoholism: Clin Exp Res 27:670-676
10. Fisher WS, Wishkovsky A, Chu FE (1990) Effects of tributyltin on defense-related activities of oyster hemocytes. Arch Environ Contam Toxicol 19:354-360
11. Fleisher G, Koven N, Kamiya H, Henle W (1982) A non-X-linked syndrome with susceptibility to severe Epstein-Barr virus infections. J Pediatr 100:727-730
12. Galli C, Viviani B, Marinovich M (1993) Cell cultures: a tool for the study of mechanisms of toxicity. Toxicol in Vitro 7:559-568
13. Gershenfeld HK, Hershberger RJ, Shows TB, Weissman IL (1988). Cloning and chromosomal assignment of human cDNA encoding a T cell- and natural killer cell-specific trypsin-like serine protease. Proc Natl Acad Sci U S A 85:184
14. Ghoneum M, Hussein AE, Gill G, Alfred LJ (1990) Suppression of murine natural killer cell activity by tributyltin: in vivo and in vitro assessment. Environ Res 52:78-186
15. Hanna N (1980) Expression of metastatic potential of tumor cells in young nude mice is correlated with low levels of natural-killer cell mediated cytotoxicity. Int J Cancer 26:675-690
16. Hanson RD, Grisolano JL, Ley TJ (1993) Consensus AP-1 and CRE motifs upstream from the human cytotoxic serine protease B (CSP-B/CGL-1) gene synergize to activate transcription. Blood 82:2749-2757
17. Holm S (1979) A simple sequentially rejective multiple test procedure. Scand J Statist 6:65-70
18. Kannan K, Falandysz J (1997) Butyltin residues in sediment, fish, fish-eating birds, harbour porpoise and human tissues from the Polish coast of the Baltic Sea. Mar Pollut Bull 34:203-207
19. Kannan K, Tanabe S, Iwata H, Tatsukawa R (1995a) Butyltins in muscle and liver of fish collected from certain Asian and Oceanian countries. Environ Pollut 90:279-290
20. Kannan K, Tanabe S, Tatsukawa R (1995b) Occurrence of butyltin residues in certain foodstuffs. Bull Environ Contam Toxicol 55:510-516
21. Kannan K, Tanabe S, Tatsukawa R, Williams RJ (1995c) Butyltin residues from Australia, Papua New Guinea and the Solomon Islands. Int J Environ Anal Chem 61:263-273
22. Kannan K, Senthilkumar K, Giesy JP (1999) Occurrence of butyltin compounds in human blood. Environ Sci Technol 33:1176-1179
23. Kiessling R, Haller O (1978) Natural killer cells in the mouse: an alternative surveillance mechanism? Contemp Top Immunobiol 8:171-201
24. Kimbrough RD (1976) Toxicity and health effects of selected organotin compounds: a review. Environ. Health Perspect 14:51-56
25. Kobayashi M, Fitz L, Ryan M, Hewick RM, Clark SC, Chan S, Loudon R, Sherman F, Perussia B, Trinchieri G (1989) Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med 170:827-845
26. Lanier LL, Benike CJ, Phillips JH, Engleman EG (1985) Recombinant IL-2 enhanced natural killer cell-mediated cytotoxicity in human lymphocyte subpopulations expressing the Leu-7 and Leu-11 antigens. J Immunol 134:794-801
27. Laughlin RB, Linden O (1985) Fate and effects of organotin compounds. Ambio 14:88-94
28. Liu C-C, Perussia ZA, Cohn ZA, Young JD-E (1986) Identification and characterization of a pore-forming protein of human peripheral blood natural killer cells. J Exp Med 164:2061
29. Lotzova E (1993) Definition and function of natural killer cells. Nat Immun 12:169-176
30. Moretta L, Biassoni R, Mingari MC, Moretta A (2002) Natural killer cells: a mystery no more. Scand J Immunol 55:229-232
31. + NK cells. J Immunol 148:2429-2436
32. Odman-Ghazi SO, Hatcher F, Whalen MM (2005) Persistent immunotoxic effects of tributyltin can be reversed by interleukin 2. Environ Toxicol Pharmacol 19:25-31
33. Ortaldo JR, Mason AT, Gerard JP, Henderson LE, Hopkins RF, Herberman RB, Rabin H (1984) Effects of natural and recombinant IL-2 on regulation of IFN-gamma production and natural killer activity: lack of involvement of Tag antigen for these immunoregulatory effects. J Immunol 133:779-783
34. Podack ER (1992) Perforin: structure, function, and regulation. Curr Top Microbiol Immunol 178:175-184
35. Prendergast JA, Helgason CD, Bleackley RC (1992) Quantitative polymerase chain reaction analysis of cytotoxic cell proteinase gene transcripts in T cells Pattern of expression is dependent on the nature of the stimulus. J Biol Chem 267:5090-5095
36. Raj DSC, Shah H, Shah VO, Ferrando A, Bankhurst A, Wolfe R, Zager PG (2003) Markers of inflammation, proteolysis and apoptosis in ESRD. Am J Kidney Dis 42:1212-1220
37. Robertson MJ, Caligiuri MA, Manley TJ, Levine H, Ritz J (1990) Human natural killer cell adhesion molecules: Differential expression after activation and participation in cytolysis. J Immunol 145:3194-3201
38. Roper WL (1992) Toxicological profile for tin. US Department of Health and Human Services Agency for Toxic Substances and Disease Registry, USA.
39. Salcedo TW, Azzoni L, Wolf SF, Perussia B (1993) Modulation of perforin and granzyme messenger RNA expression in human natural killer cells. J Immunol 151:2511-2520
40. Smialowicz RJ, Riddle MM, Rogers RR, Luebke RW, Copeland CB (1989) Immunotoxicity of tributyltin oxide in rats exposed as adults or pre-weanlings. Toxicology 57:97-111
41. Snoeij NJ, Penninks AH, Seinen W (1987) Biological activity of organotin compounds - an overview. Environ Res 44:335-353
42. Talanian RV, Yang X, Turbov J, Casiano CA, Orth O, Froelich CJ (1997) Granule-mediated killing: pathways for granzyme B-initiated apoptosis. J Exp Med 186:1324-1331
43. Tanabe S, Prudente M, Mizuno T, Hasegawa J, Iwata H, Miyazaki N (1998) Butyltin contamination in marine mammals from north Pacific and Asian coastal waters. Environ Sci Technol 32:193-198
44. Thomas LD, Shah H, Green SA, Bankhurst AD, Whalen MM (2004) Tributyltin exposure causes decreased granzyme b and perforin levels in human natural killer cells. Toxicology 200:221-233
45. Torgensen KM, Vaage JT, Levy FO, Hansson V, Rolstad B, Tasken K (1997) Selective activation of cAMP-dependant protein kinase type I inhibits rat natural killer cell cytotoxicity. J Biol Chem 272:5495-5500
46. Trapani JA, Klein JL, White PC, Dupont B (1988) Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes. Proc Natl Acad Sci U S A 85:6924
47. Trinchieri G (1989) Biology of natural killer cells. Adv Immunol 47:187-376
48. Trinchieri G, Matsumoto-Kobayashi M, Clark SC, Seehra J, London L, Perussia B (1984) Response of resting human peripheral blood natural killer cells to interleukin 2. J Exp Med 160:1147-1169
49. Van Loveren H, Krajnc EI, Rombout PJA, Blommaert FA, Vos JG (1990) Effect of ozone, hexachlorobenzene and bis(tri- n-butyltin)oxide on natural killer activity in the rat lung. Toxicol Appl Pharmacol 102:21-33
50. Vitte-Mony I, Stancou R, Bertoglio JH (1990) Functional consequences of cAMP accumulation in human natural killer cells. Implications for IL-2 and IL-4 signal transduction. J Immunol 145:4272-4278
51. Vos JG, DeKlerk A, Krajnc EI, Van Loveren H, Rozing J (1990) Immunotoxicity of bis(tri- n-butyltin) oxide in the rat: effect on thymus-dependent immunity and on nonspecific resistance following long term exposure in young versus aged rats. Toxicol Appl Pharmacol 105:144-155
52. Whalen MM, Green CB (1998) Lysis-sensitive targets stimulate an elevation in cAMP in human natural killer cells. Immunology 93:415-420
53. Whalen MM, Loganathan BG (2001) Butyltin exposure causes a rapid decrease in cyclic AMP levels in human lymphocytes. Toxicol Appl Pharmacol 171:141-148
54. Whalen MM, Loganathan BG, Kannan K (1999) Immunotoxicity of environmentally relevant concentrations of butyltins on human natural killer cells in vitro. Environ Res 81:108-116
55. Whalen MM, Williams TB, Green SA, Loganathan, BG (2002) Interleukins 2 and 12 produce recovery of cytotoxic function in tributyltin-exposed human natural killer cells. Environ Res 88:199-209
56. WHO (1980) Environmental Health Criteria 15. Tin and organotin compounds A preliminary review. WHO, Geneva
57. WHO (1990) Environmental Health Criteria 116. Tributyltin compounds. WHO, Geneva
58. Wulfing C, Purtic B, Klem J, Schatzle JD (2003) Stepwise cytoskeletal polarization as a series of checkpoints in innate but not adaptive cytolytic killing. Proc Natl Acad Sci U S A 100:7767-7772
59. Yamada S, Fuji Y, Mikami E, Kawamura N, Hayakawa J (1993) Small-scale survey of organotin compounds in household commodities. J AOAC Int 76:436-441
60. Yamamoto K, Shibata F, Miyasaka N, Miura O (2002) Human perform gene is a direct target of STAT4 activated by IL-12 in NK cells. Biochem Biophys Res Commun 297:1245-52
61. Youn BS, Liu C-C, Kim K-K, Young, JD-E, Kwon, MH, Kwon B (1991) Structure of the mouse pore-forming protein (perforin) gene: analysis of transcription initiation site, 5′ flanking sequence, and alternative splicing of 5′ untranslated regions. J Exp Med 173:813-822
62. Zager R, Shah V, Shah H, Zager P, Johnson A, Hanson S (2002) The mevalonate pathway during acute tubular injury: selected determinants and consequences. Am J Pathol 161:681-692
63. Zhang J, Scordi I, Smyth MJ, Lichtenheld MG. (1999) Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers. J Exp Med 190:1297-308