Methyl cellulose gel obstructed bone formation by GBR: An experimental study in rats

Journal of Clinical Periodontology

Volumn 32, Issue 12, 2005, Pages 1247-1253

  Lioubavina Hack, Natalia ^a   Karring, Thorkild ^a   Lynch, Samuel E ^b   Lindhe, Jan ^c  

^a UNIVERSITY OF AARHUS   (Denmark)

^b BioMimetic Therapeutics Inc   (United States)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Bone formation; GTR; Guided tissue regeneration; Insulin like growth factor; Platelet derived growth factor; Rats

Indexed keywords

BIOMATERIAL; METHYLCELLULOSE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB; POLITEF;

ANIMAL; ARTICLE; BONE DEVELOPMENT; DRUG EFFECT; GEL; MALE; MANDIBLE; METHODOLOGY; MICROCAPSULE; PERIODONTICS; RAT; WISTAR RAT;

ANIMALS; BIOCOMPATIBLE MATERIALS; CAPSULES; GELS; GUIDED TISSUE REGENERATION, PERIODONTAL; MALE; MANDIBLE; METHYLCELLULOSE; OSTEOGENESIS; PLATELET-DERIVED GROWTH FACTOR; POLYTETRAFLUOROETHYLENE; RATS; RATS, WISTAR;

EID: 28444469128     PISSN: 03036979     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2005.00791.x     Document Type: Article

References (42)

1. Becker, W., Lynch, S. E., Lekholm, U., Becker, B. E., Caffesse, R., Donath, K. & Sanchez, R. (1992) A comparison of ePTFE membranes alone or in combination with platelet derived growth factors and insulin-like growth factor-1 or demineralized freeze-dried bone in promoting bone formation around immediate extraction socket implants. Journal of Periodontology 63, 929-940.
2. Buser, D., Brägger, U., Lang, N. P. & Nyman, S. (1990) Regeneration and enlargement of jaw bone using guided tissue regeneration. Clinical Oral Implants Research 1, 22-32.
3. Canalis, E. (1981) Effect of platelet-derived growth factor on DNA and protein synthesis in cultured rat calvaria. Metabolism 30, 970-975.
4. Canalis, E. (1985) Effect of growth factors on bone cells replication and differentiation. Clinical Orthopaedics and Related Research 193, 246-263.
5. Canalis, E., McCarthy, T. L. & Centrella, M. (1988) Isolation of growth factors from adult bovine bone. Calcified Tissue International 43, 346-351.
6. Canalis, E., McCarthy, T. L. & Centrella, M. (1989) Effects of platelet-derived growth factor on bone formation in vitro. Journal of Cell Physiology 140, 530-537.
7. Cho, M-I., Lin, W-L. & Genco, R. J. (1995) Platelet-derived growth factor modulated guided tissue regenerative therapy. Journal of Periodontology 66, 522-530.
8. Chung, C. P., Kim, D. K., Park, Y. J., Nam, K. H. & Lee, S. J. (1997) Biological effects of drug - loaded biodegradable membranes for guided bone regeneration. Journal of Periodontal Research 32, 172-175.
9. Cortellini, P., Bartolucci, E., Clauser, C. & Pini Prato, G. P. (1993) Localized ridge augmentation using guided tissue regeneration in humans. Clinical Oral Implants Research 4, 203-209.
10. Dahlin, C., Gottlow, J., Linde, A. & Nyman, S. (1990) Healing of maxillary and mandibular bone defects using a membrane technique. Scandinavian Journal of Plastic Reconstructive Hand Surgery 24, 13-19.
11. Dahlin, C., Lekholm, U., Becker, W., Becker, B., Higuchi, K., Callens, A. & van Steenberghe, D. (1995) Treatment of fenestration and dehiscence bone defects around oral implants using the guided tissue regeneration technique: a prospective multicenter study. International Journal of Oral and Maxillofacial Implants 10, 312-318.
12. Dahlin, C., Linde, A., Gottlow, J. & Nyman, S. (1988) Healing of bone defects by guided tissue regeneration. Journal of Plastic and Reconstructive Surgery 81, 672-676.
13. Giannobile, W., Finkelman, R. D. & Lynch, S. E. (1994) Comparison of canine and non human primate animal models for periodontal regenerative therapy: results following a single application of PDGF/IGF-1. Journal of Periodontology 65, 1158-1168.
14. Hämmerle, C. H. F., Schmid, J., Lang, N. P. & Olah, A. J. (1995) Temporal dynamics of healing in rabbit cranial defects using guided bone regeneration. Journal of Oral and Maxillofacial Surgery 53, 167-174.
15. Hämmerle, C. H. F., Schmid, J., Olah, A. J. & Lang, N. P. (1996) A novel model system for study of experimental guided bone formation in humans. Clinical Oral Implants Research 7, 38-17.
16. Howell, T. H., Fiorellini, J. P., Paquette, D. W., Offenbacher, S., Giannobile, W. V. & Lynch, S. E. (1997) A phase I/II clinical trial to evaluate a combination of recombinant human platelet-derived growth factor-BB and recombinant human insulin-like growth factor-I in patients with periodontal disease. Journal of Periodontology 68, 1186-1193.
17. Jovanovic, S. A., Spiekermann, H. & Richter, E. J. (1992) Bone regeneration around titanium dental implants in dehisced defect sites: a clinical study. International Journal of Oral and Maxillofacial Implants 7, 233-245.
18. Karring, T., Lindhe, J. & Cortellini, P. (1997) Regenerative periodontal therapy. In: Lindhe, J., Karring, T. & Lang, N. P. (eds). Clinical Periodontology and Implant Dentistry, pp. 597-646. Copenhagen: Munksgaard.
19. Karring, T., Nyman, S., Gottlow, J. & Laurell, L. (1993) Development of the biological concept of guided tissue regeneration - animal and human studies. Periodontology 2000 1, 26-35.
20. Kostopoulos, L. & Karring, T. (1994) Guided bone regeneration in jaw bone defects. Clinical Oral Implants Research 5, 66-74.
21. Kostopoulos, L., Karring, T. & Uraguchi, R. (1994) Formation of jaw bone tuberosities by guided tissue regeneration. An experimental study in the rat. Clinical Oral Implants Research 5, 245-253.
22. Kostopoulos, L., Lioubavina, N., Karring, T. & Uraguchi, R (2001). Role of chitin beads in the formation of jaw bone by guided tissue regeneration. An experiment in the rat. Clinical Oral Implants Research 12, 325-331.
23. Lang, N. P., Hämmerle, C. H. F., Brägger, U., Lehmann, B. & Nyman, S. (1994b) Guided tissue regeneration in jaw bone defects prior to implant placement. Clinical Oral Implants Research 5, 92-97.
24. Linde, A., Thorén, C., Dahlin, C. & Sandberg, E. (1993) Creation of new bone by an osteopromotive membrane technique: an experimental study in rats. Journal of Oral and Maxillofacial Surgery 51, 892-897.
25. Lioubavina, N., Kostopoulos, L., Wenzel, A. & Karring, T. (1999) Stability of bone tissue formed by guided tissue regeneration. Clinical Oral Implants Research 10, 477-486.
26. Lundgren, D., Lundgren, A. K., Sennerby, L. & Nyman, S. (1995) Augmentation of intramembraneous bone beyond the skeletal envelope using an occlusive titanium barrier. An experimental study in the rabbit. Clinical Oral Implants Research 6, 67-72.
27. Lynch, S. E., Buser, D., Hernandez, R. A., Weber, H. P., Stich, H., Fox, C. & Williams, R. C. (1991a) Effects of the platelet-derived growth factor/insulin-like growth factor-1 combination on bone regeneration around titanium dental implants. Results of a pilot study in beagle dogs. Journal of Periodontology 62, 710-716.
28. Lynch, S. E., Nixon, J. C., Colvin, R. B. & Antoniades, H. N. (1987) Role of platelet-derived growth factors in wound healing: synergistic effects with other growth factors. Proceedings of National Academy of Science USA 84, 7696-7700.
29. Lynch, S. E., Ruiz de Castilla, G., Williams, R. C., Kristy, C. P., Howell, T. H., Reddy, M. S. & Antoniades, H. N. (1991b) The effect of short-term application of a combination of platelet-derived and insulin-like growth factors on periodontal wound healing. Journal of Periodontology 62, 458-467.
30. Lynch, S. E., Williams, R. C., Polson, A. M., Howell, T. H., Reddy, M. S., Zappa, U. E. & Antoniades, H. N. (1989) A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration. Journal of Clinical Periodontology 16, 545-548.
31. Matzen, M., Kostopoulos, L. & Karring, T. (1996) Healing of osseous submucous cleft palates with guided bone regeneration. Scandinavian Journal of Plastic Reconstructive Hand Surgery 30, 161-167.
32. Park, Y. J., Ku, Y., Chung, C. P. & Lee, S. J. (1998) Controlled release of platelet-derived growth factor from porous poly(L-lactide) membranes for guided tissue regeneration. Journal of Controlled Release 51, 201-211.
33. Park, J. B., Matsuura, M., Han, K. Y., Norderyd, O., Lin, W-L., Genco, R. L. & Cho, M. (1995) Periodontal regeneration in class III furcation defects of beagle dogs using guided tissue regerative therapy with platelet derived growth factor. Journal of Periodontology 66, 462-477.
34. Pfeilshifter, J., Oeshner, M., Newman, A., Gronwald, R. G. K., Manne, H. W. & Ceigler, R. (1990) Stimulation of bone matrix apposition, in vitro by growth factors, a comparison between insulin-like growth factor-1, platelet-derived growth factor and transforming growth factor-β. Endocrinology 127, 69-75.
35. Ross, R., Bowen Pope, D. F. & Raines, E. W. (1990) Platelet - derived growth factor and its role in health and disease. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 327, 155-169.
36. Rutherford, R. B., Niekrash, C. E., Kennedy, J. E. & Charette, M. F. (1992) Platelet derived and insulin-like growth factors stimulate regeneration of periodontal attachment in monkeys. Journal of Periodontal Research 27, 285-290.
37. Simion, M., Baldoni, M., Rossi, P. & Zaffe, D. (1994) A comparative study of the effectiveness of e-PTFE membranes with and without early exposure during the healing period. International Journal of Periodontics and Restorative Dentistry 14, 167-180.
38. Stavropoulos, A., Kostopoulos, L., Mardas, N., Nyengaard, J. R. & Karring, T. (2001) Deproteinized bovine bone used as an adjunct to guided bone augmentation: an experimental study in the rat. Clinical Implant Dentistry and Related Research 3, 156-165.
39. Trombelli, L., Lee, M. B., Promsudthi, A., Gugliemoni, P. G. & Wikesjö, U. M. E. (1999) Periodontal repair in dogs: histologic observations of guided tissue regeneration with a prostaglandin E1 analog/methacrylate composite. Journal of Clinical Periodontology 26, 381-387.
40. Vikjaer, D., Blom, S., Hjørting-Hansen, E. & Pinholt, E. M. (1997) Effect of platelet-derived growth factor-BB on bone formation in calvarial defects: an experimental study in rabbits. European Journal of Oral Sciences 105, 59-66.
41. Wikesjö, U. M., Razi, S. S., Sigurdsson, T. J., Tatakis, D. N., Lee, M. B., Ongpipattanakul, B., Nguyen, T. & Hardwick, R. (1998) Periodontal repair in dogs: effect of recombinant human transforming growth factor-beta1 on guided tissue regeneration. Journal of Clinical Periodontology 25, 475-481.
42. Zhang, L., Leeman, E., Carnes, D. C. & Graves, D. T. (1991) Human osteoblasts synthesize and respond to platelet-derived growth factor. American Journal of Physiology 261, 348-354.