Practical method for choosing diluent that ensures the best temperature uniformity in the case of pharmaceutical microwave vacuum drying of a heat sensitive product

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 62, Issue 1, 2006, Pages 101-109

  Kelen, Akos ^a   Pallai Varsanyi, Erzsebet ^b   Ress, Sandor ^c   Nagy, Tibor ^a   Pintye Hodi, Klara ^d  

^a GEDEON RICHTER LTD   (Hungary)

^b UNIVERSITY OF PANNONIA   (Hungary)

^c BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^d UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Heat sensitive; High shear granulation; Hot spot; Microwave vacuum drying; Temperature distribution; Thermography

Indexed keywords

CALCIUM CARBONATE; CALCIUM PHOSPHATE DIBASIC; DILUENT; MANNITOL; MICROCRYSTALLINE CELLULOSE; POTATO STARCH; STARCH;

ARTICLE; DRUG STABILITY; HEAT SENSITIVITY; HIGH TEMPERATURE PROCEDURES; MICROWAVE RADIATION; THERMOGRAPHY; VACUUM;

CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DESICCATION; EXCIPIENTS; MICROWAVES; PHARMACEUTICAL PREPARATIONS; STARCH; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; THERMOGRAPHY; TIME FACTORS; VACUUM;

EID: 28444466593     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2005.07.007     Document Type: Article

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