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1
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4
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Preston SL, Drusano GL, Berman AL, Fowler CL, Chow AT, Dornseif B, Reichl V, Natarajan J, Corrado M. Pharmacodynamics of levofloxacin: a new paradigm for early clinical trials. JAMA 1998; 279:125–129.
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In vivo activities of amoxicillin and amoxicillin-clavulanate against streptococcus pneumoniae: Application to breakpoint determination
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Ambrose PG, Grasela DM, Grasela TH, Passarell J, Mayer HB, Pierce PF. Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections. Antimicrob Agents Chemother 2001; 45:2793–2797.
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Dudley MN, Ambrose PG. Pharmacodynamics in the study of drug resistance and establishing in vitro susceptibility breakpoints: ready for prime time. Curr Opin Microbiol 2000; 3: 515–521.
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Acute otitis media: Management and surveillance in an era of pneumococcal resistance—report from the drug-resistant streptococcus pneumoniae therapeutic working group
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Dowell SF, Butler JC, Giebink GS, Jacobs MR, Jernigan D, Musher DM, Rakowsky A, Schwartz B. Acute otitis media: management and surveillance in an era of pneumococcal resistance—report from the Drug-Resistant Streptococcus Pneumoniae Therapeutic Working Group. Pediatr Infect Dis J 1999; 18:1–9.
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Management of community-acquired pneumonia in the era of pneumococcal resistance: A report from the drugresistant streptococcus pneumoniae therapeutic working group
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0002031565
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Lorian V, 4th ed. Baltimore: Williams & Wilkins
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0023176033
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Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bactericidal activity and emergence of resistance
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Blaser J, Stone BB, Groner MC, Zinner SH. Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bactericidal activity and emergence of resistance. Antimicrob Agents Chemother 1987; 31:1054–1060.
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0038372082
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Free drug 24-hr AUC/MIC is the PK/PD target that correlates with in vivo efficacy of macrolides, azalides, ketolides, and clindamycin [abstr A-1264]
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San Diego, CA, Sept
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Craig WA, Kiem S, Andes DR. Free drug 24-hr AUC/MIC is the PK/PD target that correlates with in vivo efficacy of macrolides, azalides, ketolides, and clindamycin [abstr A-1264], 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, CA, Sept 27–30, 2002.
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0027457842
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Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of pseudomonas sepsis
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Drusano GL, Johnson DE, Rosen M, Standiford HC. Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsis. Antimicrob Agents Chemother 1993; 37:483–490.
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0024501170
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24
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0025619681
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Leggett JE, Ebert S, Fantin B, Craig WA. Comparative dose-effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models. Scand J Infect Dis 1990; 74:179–184.
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0029097440
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Interrelationships between pharmacokinetics and pharmacodynamics in determining dosage regimens for broadspectrum cephalosporins
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33645173009
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Characterization of the pharmacodynamics of clindamycin against streptococcus pneumoniae in a murine thigh infection model [abstr]
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Magnitude of the 24h AUC/MIC required for doxycycline against streptococcus pneumoniae in a murine thigh infection model [abstr]
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Christianson J, Andes D, Craig W. Magnitude of the 24h AUC/MIC required for doxycycline against Streptococcus pneumoniae in a murine thigh infection model [abstr], 41st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, Dec 16–19, 2001.
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0033989601
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35
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0033976135
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Bacteriologic and clinical efficacy of amoxicillin/clavulanate vs. Azithromycin in acute otitis media
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Dagan R, Johnson CE, McLinn S, Abughali N, Feris J, Leibovitz E, Burch DJ, Jacobs MR. Bacteriologic and clinical efficacy of amoxicillin/clavulanate vs. azithromycin in acute otitis media. Pediatr Infect Dis J 2000; 19:95–104.
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36
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0034838137
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Bacteriologic and clinical efficacy of high dose amoxicillin/clavulanate in children with acute otitis media
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Dagan R, Hoberman A, Johnson C, Leibovitz EL, Arguedas A, Rose FV, Wynne BR, Jacobs MR. Bacteriologic and clinical efficacy of high dose amoxicillin/clavulanate in children with acute otitis media. Pediatr Infect Dis J 2001; 20:829–837.
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0032952390
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Two pharmacodynamic models for assessing the efficacy of amoxicillin-clavulante against experimental respiratory tract infections caused by strains of streptococcus pneumoniae
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38
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0002792220
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Protein binding
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Lorian V, 3d ed. Baltimore: Williams & Wilkins
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Craig WA, Suh B. Protein Binding. In: Lorian V, Ed Antibiotics in Laboratory Medicine. 3d ed. Baltimore: Williams & Wilkins, 1991:367–402.
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Craig, W.A.1
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0015691623
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Influence of binding to the pharmacologic activity of antibiotics
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Kunin CM, Craig WA, Kornguth M, Monson R. Influence of binding to the pharmacologic activity of antibiotics. Ann NY Acad Sci 1973; 226:214–224.
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40
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0036776002
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Outcome of treatment of respiratory tract infections due to streptococcus pneumoniae, including drug-resistant strains, with pharmacokinetically enhanced amoxicillin/clavulanate
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File TM Jr, Jacobs MR, Poole MD, Wynne B. Outcome of treatment of respiratory tract infections due to Streptococcus pneumoniae, including drug-resistant strains, with pharmacokinetically enhanced amoxicillin/clavulanate. Int J Antimicrob Agents 2002; 20:235–247.
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File, T.M.1
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41
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0031772904
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Continuous vs intermittent infusion of cefuroxime for the treatment of community-acquired pneumonia
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Ambrose PG, Quintiliani R, Nightingale CH. Continuous vs intermittent infusion of cefuroxime for the treatment of community-acquired pneumonia. Infect Dis Clin Prac 1997; 7:463–470.
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42
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85057445566
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-
Comparative in vivo activity of HMR 3647, azithromycin, clarithromycin, and roxithromycin against s. Pneumoniae and s. aureus [abstr f258], Toronto, Sept 28-Oct
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Vesga O, Andes D, Craig WA. Comparative in vivo activity of HMR 3647, azithromycin, clarithromycin, and roxithromycin against S. pneumoniae and S. aureus [abstr F258], 37th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Sept 28-Oct 1, 1997.
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37th Interscience Conference on Antimicrobial Agents and Chemotherapy
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Vesga, O.1
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43
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0031854524
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44
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0036093097
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Characterization of the pharmacodynamics of the new fluoroquinolone, gatifloxaxin, in murine thigh and lung infection models
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0038335015
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Pharmacodynamics of a novel des-F(6)-quinolone, BMS-284756, against streptococcus pneumoniae in the thigh infection model
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49
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0031052377
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Development of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of in vitro and in vivo correlation data for fluconazole, itraconazole, and Candida infections
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Rex JH, Pfaller MA, Galgiani JN, Bartlett MS, Espinel-Ingroff A, Ghannoum MA, Lancaster M, Odds FC, Rinaldi MG, Walsh TJ, Barry AL, for the NCCLS Subcommittee on Antifungal Susceptibility Testing. Development of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of in vitro and in vivo correlation data for fluconazole, itraconazole, and Candida infections. Clin Infect Dis 1997; 24: 235–247.
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