Evolutionary game theory in an agent-based brain tumor model: Exploring the 'Genotype-Phenotype' link

Journal of Theoretical Biology

Volumn 238, Issue 1, 2006, Pages 146-156

  Mansury, Yuri ^a,b   Diggory, Mark ^c   Deisboeck, Thomas S ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

Agent based; Game theory; Gliomas; Tumor modeling

Indexed keywords

GAME THEORY; TUMOR;

ARTICLE; BRAIN TUMOR; CANCER CELL; CANCER RESEARCH; CELL INTERACTION; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; EVOLUTION; GENOTYPE; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; PHASE TRANSITION; PHENOTYPE; PRIORITY JOURNAL; SIMULATION; TUMOR MODEL; VELOCITY;

BRAIN NEOPLASMS; CELL MOVEMENT; CELL PROLIFERATION; COMPUTER SIMULATION; GAME THEORY; GENOTYPE; HUMANS; MODELS, GENETIC; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PHENOTYPE;

EID: 28444444199     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2005.05.027     Document Type: Article

References (30)

1. L.A. Bach, S.M. Bentzen, J. Alsner, and F.B. Christiansen An evolutionary-game model of tumour-cell interactions: possible relevance to gene therapy Eur. J. Cancer 37 2001 2116 2120
2. J.S. Brown, and T.L. Vincent Organization of predator-prey communities as an evolutionary game Evolution 46 1992 1269 1283
3. T.S. Deisboeck, M.E. Berens, A.R. Kansal, S. Torquato, A.O. Stemmer-Rachamimov, and E.A. Chiocca Pattern of self-organization in tumor systems: complex growth dynamics in a novel brain tumor spheroid model Cell Prolif 34 2001 115 134
4. L.A. Dugatkin, and H.K. Reeve Game Theory and Animal Behavior Eds. 1998 Oxford University Press Oxford
5. J.P. Freyer, and R.M. Sutherland Regulation of growth saturation and development of necrosis in EMT6/Ro multicellular spheroids by the glucose and oxygen supply Cancer Res 46 1986 3504 3512
6. R.A. Gatenby, and E.T. Gawlinski A reaction-diffusion model of cancer invasion Cancer Res 56 1996 5745 5753
7. R.A. Gatenby, and T.L. Vincent An evolutionary model of carcinogenesis Cancer Res 63 2003 6212 6220
8. R.A. Gatenby, and T.L. Vincent Application of quantitative models from population biology and evolutionary game theory to tumor therapeutic strategies Mol. Cancer Ther. 2 9 2003 919 927
9. P. Ghosh, and U.N. Singh Intercellular communication in rapidly proliferating and differentiated C6 glioma cells in culture Cell Biol. Int. 21 9 1997 551 557
10. A. Giese, M.A. Loo, N. Tran, D. Haskett, S. Coons, and M.E. Berens Dichotomy of astrocytoma migration and proliferation Int. J. Cancer 67 1996 275 282
11. I. Gonzalez-Garcia, R.V. Sole, and J. Costa Metapopulation dynamics and spatial heterogeneity in cancer Proc. Natl Acad. Sci. USA 20 2002 13085 13089
12. W.D. Hamilton Extraordinary sex ratios Science 156 1967 477 488
13. A.R. Kansal, S. Torquato, E.A. Chiocca, and T.S. Deisboeck Emergence of a subpopulation in a computational model of tumor growth J. Theor. Biol. 207 3 2001 431 441
14. N.M. Kumar, and N.B. Gilula The gap junction communication channel Cell 84 1996 381 388
15. Y. Mansury, and T.S. Deisboeck The impact of 'search-precision' in an agent-based tumor model J. Theor. Biol. 224 2003 325 337
16. Y. Mansury, and T.S. Deisboeck Simulating 'structure-function' patterns of malignant brain tumors Physica A 331 2004 219 232
17. L. Mariani, C. Beaudry, W.S. McDonough, D.B. Hoelzinger, T. Demuth, K.R. Ross, T. Berens, S.W. Coons, G. Watts, J.M. Trent, J.S. Wei, A. Giese, and M.E. Berens Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: a cDNA microarray analysis Neurooncology 53 2001 161 176
18. W.S. McDonough, A. Johansson, H. Joffee, A. Giese, and M.E. Berens Gap junction intercellular communication in gliomas is inversely related to cell motility Int. J. Dev. Neurosci. 17 5-6 1999 601 611
19. M.A. Nowak, and R.M. May Evolutionary games and chaos Nature 359 1995 826 829
20. M.A. Nowak, and K. Sigmund Oscillation in the evolution of reciprocity J. Theor. Biol. 137 1989 21 26
21. M.A. Nowak, and K. Sigmund Evolutionary dynamics of biological games Science 303 2004 793 799
22. C.D. Roskelley, and M.J. Bissel The dominance of the microenvironment in breast and ovarian cancer Semin. Cancer Biol. 12 2002 97 104
23. L.M. Sander, and T.S. Deisboeck Growth patterns of microscopic brain tumors Phys. Rev. E 66 2002 051901
24. A. Sasaki, and M.A. Nowak Mutation landscapes J. Theor. Biol. 224 2003 241 247
25. J.R. Shapiro Biology of gliomas: heterogeneity, oncogenes, growth factors Semin. Oncol. 13 1986 4 15
26. J.M. Smith, and G.R. Price The logic of animal conflict Nature 246 1973 15 18
27. R.V. Sole, and J. Bascompte Stability and complexity in spatially-extended two-species competition J. Theor. Biol. 159 1992 469 480
28. I.P.M. Tomlinson Game-theory interactions between tumour cells Eur. J. Cancer 33 1997 1495 1500
29. I.P.M. Tomlinson, and W.F. Bodmer Modelling the consequences of interactions between tumour cells Brit. J. Cancer 75 1997 157 160
30. D. Zhu, G.M. Kidder, S. Caveney, and C.C. Naus Growth retardation in glioma cells cocultured with cells overexpressing a gap junction protein Proc. Natl Acad. Sci. USA. 89 21 1992 10218 10221