Crystal structure of 1, 1-dichloro-1a, 3-diphenyl-1, 1a, 2, 3-tetrahydro-azirino [2, 1-d] [1, 5]benzothiazepine (C 22H 17Cl 2NS)

Jiegou Huaxue

Volumn 17, Issue 5, 1998, Pages 349-352

  Xu, Jia Xi ^a   Lan, Ruo Xi ^a   Jin, Sheng ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

1, 1a, 2, 3 tetrahydro azirino 2, 1 d 1, 5 benzothiazepine; 1, 5 benzothiazepine; Crystal structure

Indexed keywords

EID: 2842543612     PISSN: 02545861     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Bock M G, Dipardo R M, Evans B E et al. Benzodiazepine Gastrin and Brain Cholecystokinin Receptor Ligands, L-365, 260. J. Med. Chem. , 1989, 32: 13-16
2. Bunin B A, Plunkett M J, Ellman J A. The Combinatorial Synthesis and Chemical and Biological Evalution of a 1, 4-Benzodiazepine Library. Proc. Natl. Acad. Sci. USA, 1994, 91: 4708-81
3. Lloyds D, Cleghom H P. 1, 5-Benzodiazepines. Adv. Heterocyclic Chem. , 1974, 17: 27-43
4. Aversa M C, Giannetto P, Feriazzo A. Tetrahydroisoxazolo [2, 3-d][1, 4] benzodiazepinone Ring System: Synthesis, Stereochemistry, and Conformation. J. Chem. Soc. Perkin Trans. 1, 1982, 2701-2705
5. Takahashi M, Takada T, Sakagami T. Addition of Dihalocarbenes to 3H-1, 5-Benzodiazepines. Synthesis of 2H-Bisazirino [1, 2-a, 2′, 1′-d][1, 5]benzodiazepines. J. Heterocyclic Chem. , 1987, 24: 797-799
6. Campiani G, Nacci V, Fiorini I et al. Pyrrolobenzbthiazepines and Pyrrolobenzoxazepines: Novel and Specific Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors with Antiviral Activity. J. Med. Chem. , 1996, 39: 2672-2680
7. Xu Jiaxi, Jin Sheng. New Heterocyclic System Synthesis IV: 4a, 5, 6, 12-Tetrahydro-1H-1, 3-Oxazino[3, 2-d][1, 5] benzothiazepin-1-one. Chin. Chem. Letts., 1992, 3: 181-182
8. Xu Jiaxi, Jin Sheng, Xing Qiyi. Cycloaddition Reaction of Benzoheteroazepine: Synthesis of 4a, 5, 6, 12-Tetrahydro-1H-1, 3-Oxazino[3, 2-d][1, 5]benzothiazepin-1-one and 1H, 7H-1, 3-Oxazino[3, 2-d][1, 5]benzodiazepin-1-one. Phosphorus, Sulfur and Silicon, 1998 (in press).
9. Xu Jiaxi, Jin Sheng. New heterocyclic System Synthesis M : The Cycloaddition Derivatives of 1, 5-Benzothiazepine and 1, 5-Benzodiazepine. Chin. Chem. Letts. , 1994, 5: 557-560
10. Wu Haitao, Jin Sheng. New Heterocyclic System Synthesis V : The Synthesis and Characteristics of 1, 3a, 5-Trisubstitut-ed-3a, 4, 5, 11-Tetrahydro-1, 2, 4-Oxadiazolino[5, 4-d][1, 5]benzodiheteropines. Chin. Chem. Letts. , 1993, 4: 95-96
11. 2OCIS). Jiegou Huaxue, 1992, 11: 297-311
12. Xu Jiaxi, Jin Sheng, Zhang Zeying et al. 7-Benzoyl-2, 3, 4a, 6-Tetraphenyl-4a, 5, 6, 12-Tetrahydro-1H, 7H-1, 3-Oxazino[3, 2-d][1, 5]benzodiazepin-1-one. Acta Cryst. , 1998, C54: 666-668
13. Xu Jiaxi, Jin Sheng. Synthesis and Crystal Structure of 5-(2-Bromophenyl)-1, 3, 3a-Triphenyl-3a, 4, 5, 11-Tetrahydro-3H-1, 2, 4-Triazolo[4, 3-d][1, 5]benzothiazepine; Acta Sci Nat, Univ Pekin, 1998, 34: 442-446
14. Xu Jiaxi, Jin Sheng, Zhang Zeying et al. Synthesis and Crystal Structure of 1, 3, 3a, 5-Tetraphenyl-3a, 4, 5, 11-Tetrahydro-3H, 6H-1, 2, 4-Triazolo[4, 3-d][1, 5]benzodiazepine. Chem. J. Chin. Univ. , 1998, 19: 1070-1073
15. Li G P, Jiang L H, Li P W et al. Structure Comparison of Benzothiazepine Derivatives. Jiegou Huaxue, 1994, 13: 293-299