Challenges and opportunities for combination therapy in chronic obstructive pulmonary disease

Proceedings of the American Thoracic Society

Volumn 2, Issue 4, 2005, Pages 391-393

  Rennard, Stephen I ^a,b   Stoner, Julie A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Biostatistics; Clinical trials; Drug development; Outcome measures

Indexed keywords

CHRONIC OBSTRUCTIVE LUNG DISEASE; CONFERENCE PAPER; FORCED EXPIRATORY VOLUME; HEALTH STATUS; MEDICAL RESEARCH; OUTCOMES RESEARCH; PHYSICAL EXAMINATION; SMOKING CESSATION;

DRUG THERAPY, COMBINATION; HUMANS; OUTCOME ASSESSMENT (HEALTH CARE); PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 28244493657     PISSN: 15463222     EISSN: 15463222     Source Type: Journal    
DOI: 10.1513/pats.200504-046SR     Document Type: Conference Paper

References (29)

1. Murray CJ, Lopez AD. Alternative projection of mortality by cause 1990-2020: global burden of disease study. Lancet 1997;349:1498-1504.
2. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease: NHLBI/WHO workshop report. Bethesda, MD: National Heart, Lung, and Blood Institute; 2001. Update of the Management Sections, GOLD website (www.goldcopd.com). Date updated: July 1, 2003.
3. Petty RL, Nett LM. COPD: prevention in the primary care setting. National Lung Health Education Program (NLHEP); 2001.
4. Barnes PJ, Shapiro SD, Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J 2003;22:672-688.
5. Salsburg D. The lady tasting tea: how statistics revolutionized science in the twentieth century. New York: Henry Holt and Company; 2001.
6. Hochberg Y, Tamhane A. Multiple comparison procedures. New York: Wiley, 1987.
7. Rennard SI. Treatment of stable chronic obstructive pulmonary disease. Lancet 2004;364:791-802.
8. Piquette CA, Rennard SI, Snider GL. Chronic bronchitis and emphysema. In: Murray JF, Nadel JA, editors. Textbook of respiratory medicine. Philadelphia, PA: W.B. Saunders, 2000. pp. 1187-1245.
9. Niewoehner DE, Sobonya RE. Structure-function correlations in chronic obstructive pulmonary disease. In: Baum GL, Wlinsky E, editors. Textbook of pulmonary diseases. Boston, MA: Little, Brown and Company; 1994. pp. 973-993.
10. Fletcher C, Peto R, Tinker C, Speizer F. The natural history of chronic bronchitis and emphysema. New York: Oxford University Press; 1976.
11. Anthonisen NR, Connett JE, Murray RP. Smoking and lung function of Lung Health Study participants after 11 years. Am J Respir Crit Care Med 2002;166:675-679.
12. 1. JAMA 1994;272:1497-1505.
13. Anthonisen N, Connett J, Friedman B, Glass M, Kilday DP, Mingo TS, Rudolphus A, Williams GW. Design of a clinical trial to test a treatment of the underlying cause of emphysema. Ann NY Acad Sci 1991;624:31-34.
14. O'Donnell DE. Assessment of bronchodilator efficacy in symptomatic COPD: is spirometry useful? Chest 2000;117:42S-47S.
15. O'Donnell DE, Revill SM, Webb KA. Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001;164:770-777.
16. Spencer S, Jones PW. Time course of recovery of health status following an infective exacerbation of chronic bronchitis. Thorax 2003;58:589-593.
17. Seemungal TA, Donaldson GC, Paul EA, Bestall JC, Jeffries DJ, Wedzicha JA. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;157:1418-1422.
18. Wouters EF. Chronic obstructive pulmonary disease. 5. Systemic effects of COPD. Thorax 2002;57:1067-1070.
19. Gosselink R, Troosters T, Decramer M. Peripheral muscle weakness contributes to exercise limitation in COPD. Am J Respir Crit Care Med 1996;153:976-980.
20. Sin DD, Man SF. Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? The potential role of systemic inflammation in chronic obstructive pulmonary disease. Circulation 2003;107:1514-1519.
21. van Manen JG, Bindels PJ, Dekker FW, IJzermans CJ, van der Zee JS, Schade E. Risk of depression in patients with chronic obstructive pulmonary disease and its determinants. Thorax 2002;57:412-416.
22. Praet JP, Peretz A, Rozenberg S, Famaey JP, Bourdoux P. Risk of osteoporosis in men with chronic bronchitis. Osteoporos Int 1992;2:257-261.
23. Schols AM, Slangen J, Volovics L, Wouters EF. Weight loss is a reversible factor in the prognosis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;157:1791-1797.
24. Schols AM, Mostert R, Soeters PB, Wouters EF. Body composition and exercise performance in patients with chronic obstructive pulmonary disease. Thorax 1991;46:695-699.
25. Jones PW, Quirk FH, Baveystock CM. The St George's Respiratory Questionnaire. Respir Med 1991;85(Suppl B):25-31; discussion 33-37.
26. Saey D, Debigare R, LeBlanc P, Mador MJ, Cote CH, Jobin J, Maltais F. Contractile leg fatigue after cycle exercise: a factor limiting exercise in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003;168:425-430.
27. Barnes PJ. Potential novel therapies for chronic obstructive pulmonary disease. Novartis Found Symp 2001;234:255-267; discussion 267-272.
28. Rennard S. Defective REPAIR in COPD: the American hypothesis. In: Pauwels RA, Postma, DS, editors. Long-term intervention in chronic obstructive pulmonary disease. New York: Marcel Dekker; 2004. pp. 165-200.
29. Celli BR, Cote CG, Marin JM, Casanova C, Montes de Oca M, Mendez RA, Pinto Plata V, Cabral HJ. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med 2004;350:1005-1012.