Autoantibodies against submandibular gland muscarinic cholinoceptor subtypes in primary Sjögren Syndrome

European Journal of Inflammation

Volumn 3, Issue 3, 2005, Pages 135-141

  Reina, S ^a   Sterin Borda, L ^a,b   Orman, B ^a   Borda, Enri S ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Autoantibodies; Binding assay; Cholinoceptor peptides; ELISA procedure; Muscarinic acetylcholine receptors; Sj gren syndrome

Indexed keywords

AUTOANTIBODY; IMMUNOGLOBULIN G; MUSCARINIC M1 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; PEPTIDE ANTIBODY; PIRENZEPINE; SYNTHETIC PEPTIDE; TROPICAMIDE;

ADULT; ANIMAL TISSUE; ARGENTINA; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; NONHUMAN; PATHOGENESIS; PROTEIN INTERACTION; RAT; RHEUMATOID ARTHRITIS; SJOEGREN SYNDROME; SUBMANDIBULAR GLAND;

EID: 28244491936     PISSN: 1721727X     EISSN: None     Source Type: Journal    
DOI: 10.1177/1721727X0500300305     Document Type: Article

References (20)

1. Jacobson L.T.H. and R. Manthorpe. 1995. Epidemiology of Sjögren's syndrome. Rheumatol. Eur. 24:46.
2. Manthorpe R., V. Andersen, O.A. Jensen, J.U. Prause and M. Schodt. 1986. Editorial comments to the four sets of criteria for Sjögren's syndrome. Scand. J. Rheumatol. 61:31.
3. Binder A., M.I. Snaith and D. Isenberg. 1988. Sjögren's syndrome: a study of its neurological complications. Br. J. Rheumatol. 27:275.
4. Fox P.C. and P.M. Speight. 1996. Current concepts of autoimmune exocrinopathy: immunologic mechanism in the salivary pathology of Sjögren's syndrome. Curr. Opin. Rheumatol. 7:144.
5. Atkinson J.C., I.S. Royce and R. Wellner. 1995. Anti salivary antibodies in primary Sjögren's syndrome. J. Oral. Pathol. Med. 24:206.
6. Ricchiuti V. and S. Muller. 1994. Use of peptides for the mapping of B cell epitopes recognized by anti Ro(SS-A) antibodies. In Autoimmune Disease Focus on Sjögren's syndrome. D.A. Isenberg and A.C Horsfall, eds. Scientific Publishers Limited Oxford United Kingdom, p. 101.
7. 3 muscarinic acetylcholine receptors in patients with primary Sjögren's syndrome. Invest. Ophthalmol. Vis. Sci. 39:151.
8. 3 muscarinic receptors in primary Sjögren's syndrome. Cli. Exp. Immunol. 104:454.
9. Bacman S., A. Berra, L. Sterin-Borda and E. Borda. 2001. Muscarinic acetylcholine receptor antibodies as a new marker of dry eye Sjögren's syndrome. Invest. Ophthalmol. Vis. Sci. 42:321.
10. Perez Leiros C., L. Sterin-Borda, O. Hubscher, R. Arana and E. Borda. 1999. Activation of nitric oxide signaling through muscarinic receptors in submandibular glands by primary Sjögren's syndrome antibodies. Clin. Immunol. 90:190.
11. Yamamoto H., N.E. Sims, S.P. Macauley, K.H. Nguyen., Y. Nakagawa and M.G. Humphreys-Beher. 1996. Alterations in the secretory response of non-obese diabetic (NOD) mice to muscarinic receptor stimulation. Clin. Immunol. Immunopathol. 78:245.
12. Reina S., L. Sterin-Borda, B. Orman and E. Borda. 2004. Autoantibodies against cerebral muscarinic cholinoceptors in Sjögren syndrome: functional and pathological implications. J. Neuropharmacol. 150:107.
13. Berra A., L. Sterin-Borda, S. Bacman and E. Borda. 2002. Role of salivary IgA in the pathogenesis of Sjögren syndrome. Clin. Immunol. 104:49.
14. Marczinovits I., L. Kovács, A. György, G. Tóth, L. Dorgai, J. Molnar and G. Pokorny. 2005. A peptide of human muscarinic acetylcholine receptor 3 is antigenic in primary Sjögren's syndrome. J. Autoimm. 24:47.
15. Vitali C., S. Bombardieri, R. Jonsson, H.M. Moutsopoulos, E. Alexander and S. Carsons. 1993. Preliminary criteria for the classification of Sjögren syndrome. Arthritis Rheum. 36:340.
16. Perez Leiros C., F. Rosignoli, A. Genaro, M.E. Sales, L. Sterin-Borda and E. Borda. 2002. Differential activation of nitric oxide synthase through muscarinic acetylcholine receptors in rat salivary glands. J. Auton. Nerv. Sys. 79:99.
17. Shimomura H., S. Tanaka, N. Komine, S. Shihachi, A. Imai and T. Nashida. 2004. Soluble guanylate cyclase is localized in the acinar cells and participates in amylase secretion in rat parotid gland. Arch. Oral Biol. 49:691.
18. Borda T., R. Perez Rivera, L. Joensen, R. Gomez and L. Sterin-Borda. 2002. Antibodies against cerebral M1 cholinergic muscarinic receptor from schizophrenic patients: molecular interaction. J. Immunol. 168:3661.
19. Borda E., C. Perez Leirós, J.J. Camusso, S. Bacman and L. Sterin-Borda. 1997. Differential cholinoceptor subtype-dependent activation of signal transduction pathways in neonatal versus adult rat atria. Biochem. Pharmacol. 53:959.
20. Jonsson R., H. Haga and T.P. Gordon. 2000. Current concepts on diagnosis, autoantibodies and therapy in Sjögren's syndrome. Scand. J. Rheumatol. 29:341.