Analysis of the specificity of sialy1transferases toward mucin core 2, globo, and related structures. Identification of the sialylation sequence and the effects of sulfate, fucose, methyl, and fluoro substituents of the carbohydrate chain in the biosynthesis of selectin and siglec ligands, and novel sialylation by cloned α2,3(O)sialyltransferase

Biochemistry

Volumn 44, Issue 47, 2005, Pages 15619-15635

  Chiindrasekaran, E V ^a   Xue, Jun ^a   Xia, Jie ^a   Chawda, Ram ^a   Piskorz, Conrad ^a   Locke, Robert D ^a   Neelamegham, Sriram ^b   Malta, Khushi L ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b the State University of New York   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CHROMATOGRAPHY; CLONING; MASS SPECTROMETRY; TUMORS;

BIOLOGICAL RECOGNITION; C-3 BLOCKED COMPOUNDS; LECTIN CHROMATOGRAPHY; SIALY1TRANSFERASES;

CARBOHYDRATES;

ALPHA 2,3 O SIALYLTRANSFERASE; CARBOHYDRATE; FLUORIDE; FUCOSE; LECTIN; LIGAND; METHYL GROUP; MUCIN 2; SELECTIN; SIALYLTRANSFERASE; SULFATE; UNCLASSIFIED DRUG; BETA GALACTOSIDE ALPHA 2,3 SIALYLTRANSFERASE; BETA-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE; GLOBO H; GLOBO-H; MUCIN; SIALIC ACID BINDING IG LIKE LECTIN; SIALIC ACID BINDING IG-LIKE LECTIN; TUMOR ANTIGEN;

ANIMAL CELL; ARTICLE; BIOCHEMISTRY; CARBOHYDRATE SYNTHESIS; CHROMATOGRAPHY; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ANALYSIS; FUCOSYLATION; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; RAT; SIALYLATION; SUBSTITUTION REACTION; SULFATION; CARBOHYDRATE ANALYSIS; CHEMISTRY; ENZYME SPECIFICITY; GLYCOSYLATION; MALE; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

ANIMALIA;

ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CARBOHYDRATE SEQUENCE; CARBOHYDRATES; CELL LINE, TUMOR; CHROMATOGRAPHY; CLONING, MOLECULAR; GLYCOSYLATION; HUMANS; LECTINS; LIGANDS; MALE; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MUCINS; PROSTATIC NEOPLASMS; SELECTINS; SIALYLTRANSFERASES; SUBSTRATE SPECIFICITY;

EID: 28244486825     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050246m     Document Type: Article

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