Immunnology and immunotherapy of the infections caused by Pythium insidiosum

Medical Mycology

Volumn 43, Issue 6, 2005, Pages 477-486

  Mendoza, Leonel ^a   Newton, Joseph C ^b  

^a Michigan State University ^*  (United States)

^b AUBURN UNIVERSITY   (United States)

Author keywords

Immunotherapy; Pythiosis; Pythium insidiosum

Indexed keywords

ANTIFUNGAL AGENT; CYTOKINE; FUNGUS ANTIGEN; IMMUNOMODULATING AGENT; ANTIGEN;

DATA ANALYSIS; DEGRANULATION; DIAGNOSTIC TEST; EOSINOPHIL; FUNGUS CULTURE; FUNGUS HYPHAE; HORSE DISEASE; HOST PARASITE INTERACTION; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOLOGICAL PROCEDURES; IMMUNOLOGY; IMMUNOTHERAPY; IN VITRO STUDY; INFLAMMATION; MAST CELL; MOLECULAR EVOLUTION; MYCOSIS; NONHUMAN; PATHOGENESIS; PYTHIUM; REVIEW; SEROLOGY; TH1 CELL; TH2 CELL; TREATMENT PLANNING; ANIMAL; ANIMAL DISEASE; HORSE; MICROBIOLOGY;

EQUIDAE; EQUUS CABALLUS; FUNGI; PYTHIUM; PYTHIUM INSIDIOSUM;

ANIMALS; ANTIGENS; HORSE DISEASES; HORSES; HUMANS; IMMUNOTHERAPY; MYCOSES; PYTHIUM;

EID: 28244485408     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.1080/13693780500279882     Document Type: Review

References (79)

1. De Cock WAW, Mendoza L, Padhye AA, et al. Pythium insidiosum sp. nov., the etiologic agent of pythiosis. J Clin Microbiol 1987; 25: 344-349.
2. Alexopoulos CJ, Mins CW, Blackwell M. Pythium, Oomycota. In: Introductory Mycology, 4th ed. New York: John Wiley and Sons, Inc, 1996: 683-737.
3. Moore-Landecker J. Zoosporic fungi. In: Fundamentals of the Fungi, 4th ed. New Jersey: Prentice Hall, Inc., 1996: 33-79.
4. Mendoza L, Ajello L, McGinnis MR. Infections caused by the oomycetous pathogen Pythium insidiosum. J Mycol Med 1996; 6: 151-164.
5. Miller RI. Granulomatous and neoplastic diseases of the equine skin: a review. Vet Rev Monograph No. 6. Townsville, Australia, Dept Trop Vet Sci, James Cook University, 1983: 1-52.
6. Smith F. The pathology of bursattee. Vet J 1884; 19: 16-17.
7. Drouin V. Su rune nouvelle mycose du cheval. Recl Med Vet 1896; 3: 337-344.
8. Fish PA. A historical investigation of two cases of an equine mycosis, with a historical account of the supposed similar disease, called bursattee, occurring in India. 12th and 13th Annu Rep US Bur Anim Ind 1895-1896; 229-259.
9. Thompson JJ, Young JM. The Florida "Horse-Leech" 1893-1894 10th and 11th Annual Report of the Bureau of Animal Industry, USA, 1986; 97-98.
10. de Hann J, Hoogkamer LJ. Hyphomycosis destruens. Veeartsenijk Bl v Ned Indie 1901; 13: 350-374.
11. de Hann J. Bosartige schemmelkrankheit des Pferdes (Hyphomycosis destruens equi). Zentralbl Bakt Parasitenkd Infektionskr Hyg Abt 1 Orig 1902; 31: 758-763.
12. Witkamp J. Bijdrage tot de kennis van der hyphomycosis destruens. Ned Ind Bland Diergenaeskd Dierenteelt 1924; 36: 229-345.
13. Bridges CH, Emmons CW. A phycomycosis of horses caused by Hyphomyces destruens. J Am Vet Med Assoc 1961; 138: 579-589.
14. Amemiya J, Nishiyama S. On the granular dermatitis in horses which contains a kind of true fungus in the foci. Bull Fac Agric, Kagoshima University 1966; 17: 215-224.
15. Amemiya J. Granular dermatitis in the horse, caused by Pythium gracile. Bull Fac Agric, Kagoshima University. 1982; 32: 141-147.
16. Austwick PKC, Copland JW. Swamp cancer. Nature 1974; 250: 84.
17. Ichitani T, Amemiya J. Pythium gracile isolated for the foci of granular dermatitis in the horse (Equus caballus). Trans Mycol Soc Jpn 1980; 21: 263-265.
18. Shipton WA. Pythium destruens sp. nov., an agent of equine pythiosis. J Med Vet Mycol 1987; 25: 137-151.
19. Miller RI, Campbell RSF. The comparative pathology of equine cutaneous phycomysosis. Vet Pathol 1984; 21: 325-332.
20. Goad MEP. Pulmonary pythiosis in a horse. Vet Pathol 1984; 21: 261.
21. Alfaro AA, Mendoza L. Four cases of equine bone lesions caused by Pythium insidiosum. Equine Vet J 1990; 22: 295-297.
22. Brown CC, Roberts ED. Intestinal pythiosis in a horse. Aust Vet J 1988; 65: 88-89.
23. Reis Junior JL, Carvalho ECQ de, Nogueira RHG, et al. Disseminated pythiosis in three horses. Vet Micro 2003; 96: 289-295.
24. Grooters AM. Pythiosis, lagenidiosis and zygomycosis in small animals. (Emerging and re-emerging infectious diseases). In: Veterinary Clinics of North America, Small Animal Practice. Philadelphia: W. B. Sanders, 2003; 33: 695-720.
25. Miller RI. Gastrointestinal phycomycosis in 63 dogs. J Am Vet Assoc 1985; 186: 473-478.
26. Fischer JR, Pace LW, Turk JR, et al. Gastrointestinal pythiosis in Missoure dogs: eleven cases. J Vet Diagn Invest 1994; 25: 380-382.
27. Thomas RC, Lewis DT. Pythiosis in dogs and cats. Compend Contin Ed 1998; 20: 63-74.
28. Bissonnette KW, Sharp NJH, Dykstra MJ, et al. Nasal and retrobulbar mass in a cat caused by Pythium insidiosum. J Med Vet Mycol 1991; 29: 39-44.
29. Foil CSO, Short BG, Fadok VA, et al. A report of subcutaneous pythiosis in five dogs and a review of the etiologic agent Pythium spp. J Am Anim Hosp Assoc 1984; 20: 959-966.
30. Miller RI, Olcott BM, Archer M. Cutaneous pythiosis in beef calves. J Am Vet Med Assoc 1985; 186: 984-986.
31. Tabosa IM, Riet-Correa F, Nobri VMT, et al. Outbreaks of pythiosis in two flocks of sheep in Northeastern Brazil. Vet Pathol 2004; 41: 412-415.
32. Wellehan JFX, Farina LL, Keoughan CG, et al. Pythiosis in a dromedary camel (Camelus dromedaries). J Zoo Wildlife Med 2004; 35: 564-568.
33. Camus AC, Grooters AM, Aquilar RF. Granulomatous pneumonia caused by Pythium insidiosum in a central American jaguar, Panthera onca. J Vet Diagn Invest 2004; 16: 567-571.
34. Imwidthaya P. Human pythiosis in Thailand. Postgrad Med J 1994; 70: 558-560.
35. Kaufman L. Penicilliosis marneffei and pythiosis: emerging tropical disease. Mycopathologia 1998; 143: 3-7.
36. Sathapatayavongs B, Leelanchaikul P, Pracharktam R, et al. Human pythiosis associated with thalassemia hemoglobinopathy syndrome. J Infect Dis 1989; 159: 274-280.
37. Tanphaichitra D. Tropical disease in the immunocompromised host. Rev Infect Dis 1989; 11: S1629-S1643.
38. Thianprasit M, Chaiprasert A, Inwidthaya P. Human pythiosis. Curr Trop Med Mycol 1996; 7: 43-54.
39. Thitithanyanont A, Mendoza L, Chuansumrit A, et al. Use of an immunotherapeutic vaccine to treat a life-threatening human arteritic infection caused by Pythium insidiosum. Clin Infect Dis 1998; 27: 1394-1400.
40. Wanachiwanawin W, Thianprasit M, Fucharoen S, et al. Fatal arteritis due to Pythium insidiosum infection in patients with thalassemia. Trans Roy Soc Trop Med Hyg 1993; 87: 296-298.
41. Wanachiwanawin W, Mendoza L, Visuthisakchai S, et al. Efficacy of immunotherapy using antigens of Pythium insidiosum in the treatment of vascular pythiosis in humans. Vaccine 2004; 22: 3613-3621.
42. Prasertwitayakij N, Louthrenoo W, Kasitanon N, et al. Human pythiosis, a rare cause of arteritis:case report and literature review. Sem Arthr Rheumat 2003; 33: 204-214.
43. Krajaejun T, Kunakorn M, Niemhom S, et al. Development and evaluation of an in-house enzyme-linked immunosorbent assay for early diagnosis and monitoring of human pythiosis. Clin Diagnos Lab Immunol 2002; 9: 378-382.
44. Miller RI, Campbell RS. Immunological studies on equine phycomycosis. Aust Vet J 1982; 58: 227-31.
45. Miller RI. Treatment of equine phycomycosis by immunotherapy and surgery. Aust Vet J 1981; 57: 377-382.
46. Mendoza L, Mandy W, Glass R. An improved Pythium insidiosum-vaccine formulation with enhanced immunotherapeutic properties in horses and dogs with pythiosis. Vaccine 2003; 21: 2797-2804.
47. Mendoza L, Villalobus J, Calleja CE, et al. Evaluation of two vaccines for the treatment of pythiosis insidiosi in horses. Mycopathologia 1992; 118: 89-95.
48. Mendoza L, Nicholson V, Precott JF. Immunoblot analysis of the humoral immune response to Pythium insidiosum in horses with pythiosis. J Clin Microbiol 1992; 30: 2980-2983.
49. Kaufman L, Mendoza L, Standard P. Immunodiffusion test for diagnosing subcutaneous zygomycosis. J Clin Microbiol 1990; 28: 1887-1890.
50. Mendoza L, Kaufman L, Standard P. Immunodiffusion test for diagnosis and monitoring pythiosis in horses. J Clin Microbiol 1986; 23: 813-816.
51. Pracharktam R, Chantrakool PJ, Sathapatayavongs B, et al. Immunodiffusion test for diagnosing and monitoring of human pythiosis. J Clin Microbiol 1991; 29: 2661-2662.
52. Imwidthaya P, Srimuang S. Immunodiffusion test for diagnosing human pythiosis. Mycopathologia 1989; 106: 109-112.
53. Mendoza L, Kaufman L, Standard P. Antigenic relationship between the animal and human pathogen Pythium insidiosum. J Clin Microbiol 1987; 25: 2159-2162.
54. Brown CC, McClure JJ, Triche P, et al. Use of immunohistochemical methods for diagnosis of equine pythiosis. Am J Vet Res 1988; 11: 1866-1868.
55. Mendoza L, Kaufman L, Mandy W, Glass R. Serodiagnosis of human and animal pythiosis using an enzyme-linked immunosorbent assay. Clin Diagn Lab Immunol 1997; 4: 715-718.
56. Rosa PS. Development and evaluation of serological tests to detect pythiosis in horses. MS thesis, Louisiana State University, Baton Rouge, LA, USA. 1993; 1-120.
57. Vanittanakom N, Supabandhu J, Khamwan C, et al. Identification of emerging human-pathogenic Pythium insidiosum by serological and molecular assay-based methods. J Clin Microbiol 2004; 42: 3970-3974.
58. Grooters AM, Leise BS, Lopez MK, et al. Development and evaluation of an enzyme-linked immunosorbent assay for the serodiagnosis of pythiosis in dogs. J Vet Intern Med 2002; 16: 142-146.
59. Santurio JM, Leal AT, Leal ABM, et al. Three types of immunotherapeutics against pythiosis insidiosi developed and evaluated. Vaccine 2003; 21: 2535-2540.
60. Hutchens M, Mendoza L. Development of a simplified latex agglutination test for the rapid diagnosis of the infections caused by Pythium insidiosum. 102nd General Meeting of the American Society for Microbiology, Salt Lake City, Utah, USA May, 2002; 124.
61. Ravishankar JP, Davis CM, Davis DJ, et al. Mechanics of solid tissue invasion by the mammalian pathogen Pythium insidiosum. Fungal Genet Biol 2001; 34: 167-165.
62. Alfaro AA, Mendoza L. Four cases of equine bone lesions caused by Pythium insidiosum. Equine Pet J 1990; 22: 295-297.
63. Mendoza L, Alfaro AA. Equine pythiosis in Costa Rica: report of 39 cases. Mycopathologia 1986; 94: 123-129.
64. Schurko AM, Mendoza L, Levesque CA, et al. A molecular phylogeny of Pythium insidiosum. Mycol Res 2003; 107: 537-544.
65. Amemiya J. Isolation of a fungus of the Mortierellaceae from an equine granular dermatitis III. Bull Fac Agric, Kagoshima University 1969; 19: 31-50.
66. Miller RI, Campbell RS. Experimental pythiosis in rabbits. Sabouraudia 1983; 21: 331-341.
67. Patino-Meza, F. Role of the zoospores of Pythium insidiosum in the experimental reproduction of pythiosis in susceptible species. DVM thesis, National University, Heredia, Costa Rica. 1988; 1-31.
68. Leal ABM, Lubeck I, Santurio JM, et al. Pitiose experimental en coelhos. Proceedings of the III Congreso Brasileiro de Micologia, Águas de Lindóia, Brazil. 2001; 123-124.
69. Leal AT, Santurio JM, Leal AMB, et al. Resposta sorológica de coelhos immunizados com antígenos de Pythium insidiosum associados a diferentes adjuvantes. Proceedings III Congreso Brasileiro de Micologia, Águas de Lindóia, Brazil. 2001; 124-125.
70. Miller RI, Wold D, Lindsay WA, et al. Complications associated with immunotherapy of equine phycomycosis. J Am Vet Med Assoc 1985; 186: 984-986.
71. Hensel P, Craig EG, Medleau L, et al. Immunotherapy for treatment of multicentric cutaneous pythiosis in a dog. J Am Vet Med Assoc 2003; 223: 215-218.
72. Burke DS. Vaccine therapy for HIV. a historical review of the treatment of infectious diseases by active specific immunization with microbe-derived antigens. Vaccine 1993; 11: 883-890.
73. Standford JL. The history and future of vaccination and immunotherapy for leprosy. Trop Geograph Med 1994; 46: 93-107.
74. Convit J, Ulrich M, Fernandez CT, et al. The clinical and immunological spectrum of american cutaneous leshmaniasis. Trans R Soc Trop Med Hyg 1993; 87: 444.
75. Gudding R, Lund A. Immunoprophylaxis of bovine dermatophytosis. Can Vet J 1995; 36: 302-306.
76. Newton JC, Ross PS. Equine pythiosis: an overview of immunotherapy. Compendium 1993; 15: 491-493.
77. Monteiro AB. Immunoterapia da pitiosis eqüina: teste de eficácia de um imunobiológico e avaliação leucocitária em animais infectados naturalmente pelo Pythium insidiosum. MS-DVM thesis. UFSM, Santa Maria, Rio Grande do Sur, Brasil. 1999; 1-52.
78. Dixon DM, Casadavall A, Klein B, et al. Development of vaccines and their use in the prevention of fungal infections. Med Mycol 1998; 36: 57-67.
79. The Jordan Report. Accelerated development of vaccines. National Institute of Health, USA 2000; 17.